Weight and Metabolism

Let me start by explaining what "pathophysiology" actually means — because this word gets thrown around in medicine all the time, and it's worth understanding. Physiology is how the body normally works (your heart pumps blood, your lungs bring in oxygen). Pathophysiology is the story of what happens when things go wrong — the behind-the-scenes explanation of how disease disrupts normal function. N...

This episode is about understanding what's really at stake when obesity goes untreated — not to scare you, but to give you clarity on why this work matters so much. Let me start by explaining two critical medical terms: mortality (death) and morbidity (illness and its impact on quality of life). Think of a hurricane: mortality is how many people it kills, morbidity is how many survive but live wit...

Let's talk about something that doesn't get addressed enough: the stigma, bias, and discrimination that people with obesity face every single day. Obesity stigma exists because of oversimplification, cultural beauty standards, medical bias, harmful language, and — yes — legal discrimination . In many places, it's still legal to deny someone a job, charge higher insurance premiums, or refuse accomm...

This is the question I get asked most often — and the answer matters more than you might think. In this episode, we're tackling the science, the stigma, and the uncomfortable truth: your weight is not your fault. If you've ever been told to "just eat less and move more," if you've been blamed, judged, or dismissed because of your weight — this episode is for you. Because obesity isn't a willpower...

Before we dive into all the science, protocols, and practical tools — let me tell you why I'm really here. In this episode, I'm pulling back the curtain on my own journey: from vanilla scones and lattes to oats and smoothies (thanks to my son for that wake-up call), from primary care physician to triple board-certified specialist in family medicine, obesity medicine, and lifestyle medicine. I shar...

Welcome to Weight and Metabolism with Dr. Deepti Sharma — your health is in your hands, and this podcast exists to help you take it back. In this very first episode, Dr. Deepti Sharma introduces the heart and mission behind this show. She breaks down what to expect — real, evidence-based conversations about weight, metabolism, hormones, nutrition, movement, sleep, stress, and the everyday habits t...