Prime Longevity Protocol
Weekly Pep Talk
Welcome to Weekly Pep Talk — where GLP-1s, peptides, and longevity get real and judgment-free. Hosted by Prime Longevity Protocol, each episode covers semaglutide, tirzepatide, peptide therapy, biohacking, weight loss, metabolic health, and wellness optimization. Real talk for Warriors who refuse to settle for average. No shame. No gatekeeping. Just real people chasing real results. New episodes every week. Come optimize with us. 🧬Nothing discussed is medical advice. Always consult your healthcare provider.
Author
Prime Longevity Protocol
Category
Podcast website
Latest episode
Jun 29, 2026
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Episodes
Weight Loss, Autoimmune Disease & Injury Recovery | Mike Sheffer & Max Plasencia | Pep-Talk Ep. 15 29.06.2026 47:32
Welcome back to another episode of Weekly Pep-Talk! In Episode 15, Mike and Max answer some of the most common questions from the peptide community, covering everything from weight loss plateaus and GLP-1 medications to autoimmune protocols and injury recovery. They explain why the number on the scale doesn't always reflect fat loss, how water retention can affect progress, and why patience is...
Episode 14: Dan Solomon on Mr. Olympia, WINFUEL, Peptides & The Future of Bodybuilding 22.06.2026 1:12:42
This is a special episode of Weekly Pep-Talk. Max and Mike sit down with Dan Solomon , President of Mr. Olympia, the fitness industry’s premier bodybuilding competition, and one of the most recognized brands in physique sports. In this episode, Dan shares the story behind his new book, WINFUEL , and the principles behind leadership, momentum, opportunity, and long-term success. What began as a boo...
Peptides vs Big Pharma- Who Controls The Future 15.06.2026 1:04:16
What happens when you combine peptides, fasting, brain optimization, and the future of medicine into one conversation? In Episode 13 of Weekly Pep-Talk , Max and Mike dive into one of their most wide-ranging discussions yet, covering peptide protocols, extended fasting, insulin resistance, mitochondrial health, growth hormone optimization, brain fog, and the evolving role peptides may play in mode...
The “Research Use Only” Peptide Truth Nobody Explains 08.06.2026 1:13:01
What does “research use only” actually mean when it comes to peptides — and what are people getting wrong? In this episode of Weekly Pep-Talk, Max and Mike Sheffer break down one of the most misunderstood topics in the peptide world: research-use peptides, sourcing, expectations, and responsible education. They also dive into listener Q&A covering HGH, IGF-1, peptide safety, recovery, muscle g...
25% Of The Peptides We Tested Were FAKE | Real Lab Results 02.06.2026 55:09
Are the peptides you’re buying actually real? In this bonus episode of Weekly Pep-Talk, Max Plasencia and Mike Sheffer reveal the results of a real peptide testing experiment after purchasing peptides from 12 different overseas suppliers and sending them to an independent third-party lab for analysis. The results were shocking: 25% of the peptides tested failed. This episode breaks down what the l...
Best Summer Shred Peptide Stack + Tesamorelin Experiment 01.06.2026 49:37
What’s the best peptide stack to get shredded for summer without losing muscle, energy, or your hair? In Episode 10 of Pep-Talk, Max Plasencia and Mike Sheffer break down their ultimate summer shred peptide stacks, including Retatrutide, Tesamorelin, Ipamorelin, Tesofensine, 5-Amino-1MQ, SLPP-332, and more. They also reveal the results of their Tesamorelin gel experiment and discuss how to avoid c...
Cancer Peptides, TRT & Longevity Hacks Q&A 25.05.2026 51:32
Can peptides improve longevity, optimize TRT, boost energy, and even support cancer recovery protocols? In Episode 9 of Pep-Talk, Max Plasencia and Mike Sheffer answer listener questions covering advanced peptide protocols, anti-aging, TRT optimization, insulin resistance, cancer-related peptides, and ATP production at the cellular level. This episode explores compounds like PNC-27, FOXO4-DRI, BPC...
GLP-1 FASTING MYTH-Are you doing it WRONG? 19.05.2026 43:17
Does Retatrutide completely change how fasting works? And are most people using GLP-1 peptides the wrong way? In Episode 8 of Pep-Talk, Max Plasencia and Mike Sheffer dive deep into the science behind GLP-1 peptides, fasting, longevity, and anti-aging optimization — including powerful compounds like Tesamorelin, Epitalon, FOXO4-DRI, SS31, and MOTS-C. We break down why so many people fail with GLP-...
Are you making the biggest mistake with GLP-1 peptides like Retatrutide or Tirzepatide without even realizing it? 11.05.2026 53:56
In Episode 7 of Pep-Talk, Max Plasencia and Mike Sheffer uncover the most common GLP-1 fat loss mistakes — from overdosing and rapid weight loss to metabolic damage and rebound weight gain. They also introduce Tessafensine, a powerful appetite-control compound that may support sustainable fat loss, better mood, and improved focus without relying on extreme GLP-1 dosing. 💡 In This Episode, You’ll...
New FDA compounding restrictions - GLP’s skyrocket 04.05.2026 1:04:58
In this episode of Pep-Talk, Max Plasencia and Mike Sheffer break down the latest FDA update and what it means for GLP-1 peptides like semaglutide and tirzepatide. With new restrictions on compounding pharmacies, prices are expected to rise significantly - and access could become more limited.💡 What You’ll Learn: What the new FDA compounding restrictions actually mean Why GLP-1 prices are about t...
PNC-27 Cancer Peptide + Peptide Reconstitution Guide 04.05.2026 1:03:05
Could PNC-27 & PNC-28 become groundbreaking peptides in future cancer research? And are you reconstituting your peptides correctly? In Episode 6 of Pep-Talk, Max Plasencia and Mike Sheffer break down one of the most talked-about peptide discussions yet. PNC-27 / PNC-28 plus a full beginner guide to peptide reconstitution, dosing calculations, bacteriostatic water vs acetic acid, and listener Q...
Peptide power: Truth, Science, Results - Covering Peptides BPC157, TB500, Tesamorelin, Retatrutide 04.05.2026 1:23:57
Today, we discuss how we personally got into the peptide world, our trials, and how it grew into a life-changing movement. Max and I discuss specific peptides and the science behind them. Reta, bpc, tb4, tb500, tesa. Skool platform questions are answered live on the weekly pep-talk! Buy Peptides online at Prime Longevity Peptides: Enter code:welcome20 for 20% off your first order: https://primel...
Peptides for Muscle Growth, Fat Loss & Biohacking (Truth Explained) 04.05.2026 1:21:49
Can peptides really help with muscle growth, fat loss, and recovery? Or is it all hype? In Episode 3 of Pep-Talk, we sit down with IFBB Pro Alex to break down bodybuilding, peptides, and biohacking - including real-world results, risks, and what actually works.💡 What You’ll Learn: -How peptides impact muscle growth & recovery-Real bodybuilding journey (from beginner to IFBB Pro)-IGF-1 LR3 ben...
The truth about peptides for healing & fat loss 04.05.2026 54:21
Most people think the “Wolverine Stack” is just BPC-157 and TB-500… but that’s not the full story. In this episode of Pep-Talk, we break down the real Wolverine peptide protocol for faster injury healing, muscle recovery, and performance. We also dive deep into women’s health, explaining the root causes of fatigue, weight gain, brain fog, and hormonal imbalance and how to fix them using a science-...
BREAKING: Peptide Shortage Crisis & Underground Solutions | The Weekly Pept Talk Ep.4 28.04.2026 59:44
Max and Mike expose what's REALLY happening with the peptide market disappearing before our eyes. Plus, discover the brain-enhancing compound neurohackers are quietly stockpiling. 🧠 Cerebrolysin: The cognitive accelerator researchers don't want mainstream 💉 Why your peptide sources are vanishing (and what to do NOW) 🔬 The testosterone recovery protocol doctors won't tell you about ⚠...
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