Unpacking Pain

Pain can show up even when scans look “fine,” and severe arthritis can exist with little to no pain - so what should you do when the usual explanations don’t add up? Holly puts Dr. Megan on the hot seat for a listener-driven lightning round, tackling five common questions people ask when they’re trying to make sense of chronic pain. Learn how to think about medication as a tool (and when it may be...

If you’ve ever wondered why surgery can “fix” the structure but not always fix the pain, you’re not alone. Dr. Megan Steele and Holly Osborne explore what really influences surgical outcomes, especially for people living with chronic pain. Join them as they break down why pain isn’t purely mechanical, how your nervous system’s threat detection can shape recovery (even under anesthesia), and why sc...

In this episode, we discuss a personal experience involving violent assault, injury, and subsequent surgeries. Listener discretion is advised. If these topics are difficult for you, you may wish to skip this episode or listen when you feel supported. If you’ve had pain for years, you’ve probably been asked to summarize your whole story in minutes, and then felt the conversation rush straight to te...

Did you know researchers are teaching kids about pain before they experience it - and it might prevent chronic pain in adulthood? Between 20-25% of children with acute injuries develop chronic pain, but they're not just small adults. Their brains are more plastic, more vulnerable, and remarkably more responsive to intervention. Dr. Megan Steele and Holly Osborne explore what makes pediatric pain d...

Anyone selling you a magic bullet for chronic pain is either lying or doesn't understand how pain actually works. But here's what does work: your brain's ability to literally rewire itself. Holly and Dr. Megan Steele explore the growing body of research showing that mindfulness, breathwork, and visualization aren't just "woo-woo" practices - they create measurable changes in your brain that reduce...

Why do women make up 70% of chronic pain sufferers? The answer involves more than just biology. Dr. Megan and Holly examine how hormones, pain thresholds, and social conditioning create vastly different pain experiences for men and women. You'll discover: Why pain thresholds change dramatically at puberty and menopause How testosterone acts as a buffer and estrogen fluctuations trigger pain Insigh...

Why do two people with the same injury have completely different pain journeys - and what does a zip code have to do with it? Today we dig into the often-overlooked social side of persistent pain: the way income, work conditions, food access, relationships, and even cultural expectations can ramp pain up or help dial it down. Dr. Megan and Holly explore how: Socioeconomic status and access to care...

What if the pain you feel long after an injury has “healed” isn’t a sign that your body is broken, but that your nervous system is stuck in protection mode? Dr. Megan and Holly break down what’s happening in the brain and body when pain lingers, scans look “normal,” and daily life starts to shrink. They explore how chronic pain and emotions are tightly linked, and why anxiety, depression, shame, a...

Why does chronic pain spread from one area of your body to another? And why does it often feel worse at night when you're trying to sleep? When pain persists for months or years, your nervous system doesn't just stay the same - it changes. Your nerves lose their protective coating, your spinal cord becomes more sensitized, and your brain actually develops structural changes that keep you locked in...

What happens when a pain researcher teams up with someone who’s lived with chronic pain for decades? In this bonus conversation, meet the voices behind Unpacking Pain. Dr. Megan Steele, a physical therapist and pain science researcher, explains why evidence-based guidance is still hard to find and what the data actually says. Holly Osborne shares the lived experience side - what helped, what didn’...

Why does a system designed to protect us sometimes keep the alarm blaring long after the danger has passed? Chronic pain isn’t just about damaged tissue. Dr. Megan and Holly break down how the body’s warning system can stay on high alert and why understanding the biopsychosocial model - biology, psychology, and social context - can change the way you navigate persistent pain. You’ll hear clear exa...

What if chronic pain isn’t only a body problem, but a biology–psychology–social puzzle you can learn to solve? Meet your guides: Dr. Megan Steele, a physical therapist and pain science researcher, and Holly, a long‑time pain experiencer with a thousand practical questions. Together, they break persistent pain into clear, human terms. You’ll hear candid stories, simple explanations of what’s happen...