Jessica Duffin
This EndoLife
From the best surgery to natural therapies, This EndoLife Podcast empowers you to live and thrive with endometriosis and its co-conditions through a holistic, functional medicine approach. I’m covering all the topics that often aren’t discussed in the doctor’s office, whether that’s how to eat well for endometriosis, how to treat the endo belly or just what exactly is SIBO? Come join myself (and my guests!) as we dive into anti-inflammatory nutrition, gut health, hormones, pain science, mental health, sex, energy and living life well with endo.
Author
Jessica Duffin
Category
Podcast website
Latest episode
Jul 5, 2026
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Episodes
What Does the Latest Research Tell Us About Endo Belly and the Microbiome of People With Endo? 05.07.2026 10:50
As I am still recovering from covid, today’s episode is a short bite sized episode looking at what the recent research is telling us about the endo belly and the gut microbiome of people with endo. References 1) https://pmc.ncbi.nlm.nih.gov/articles/PMC10316551/ 2) https://pubmed.ncbi.nlm.nih.gov/28303579/ 3) Endometriosis and irritable bowel syndrome: A systematic review and meta-analyses - PMC 4...
Could SIBO Antibiotics Also Help Treat Endometriosis? 31.05.2026 20:02
Antibiotics, understandably, have a bad reputation because of how much they’ve been overused in the past few decades, and the impact that has had on our gut microbiomes and overall health, not to mention, resistance development. So, when it comes to antibiotics for SIBO, most of my clients are initially hesitant to consider them, and will typically opt for antimicrobial herbs instead. However, the...
What Are Lipopolysaccharides and What’s Their Role in Endometriosis Growth and Pain? 24.05.2026 15:33
Today I want to talk about lipopolysaccharides and their role in endo growth and pain. References 1) https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1363455/full 2) Bacterial contamination hypothesis: a new concept in endometriosis - PMC , Evaluation of microecological therapy in endometriosis through modulation of the gut microbiota | European Journal of Medical Re...
Which Type of SIBO Gases Are Endo Patients Most Likely to Have, and What Are the Symptoms? 17.05.2026 13:22
Today I want to talk very briefly on endo belly and IBS symptoms, and the three SIBO type gases and the specific symptoms they can cause, so that you can look for clues as to whether SIBO is behind your gut issues. References: https://pubmed.ncbi.nlm.nih.gov/29228433/ , https://pubmed.ncbi.nlm.nih.gov/12591062/ , https://pubmed.ncbi.nlm.nih.gov/22262197/ , https://pubmed.ncbi.nlm.nih.gov/24627585/...
How, When and Why I Use Low Dose Naltrexone with Endo, SIBO or MCAS Clients 09.05.2026 17:36
LDN stands for low dose naltrexone. It is an immune modulating drug that also regulates the body’s pain relief system. It is non-addictive and safe, but it can come with side effects, so we’ll get to that - as thankfully, they can be reduced or eradicated entirely. Low-dose naltrexone works in two ways: it blocks opioid receptors which forces the body to increase its levels of other natural pain r...
SIBO, Gut Dysbiosis, and Elevated Oestrogen Levels 30.04.2026 20:50
There are several reasons why SIBO and gut dysbiosis can influence endo growth, but today, I want to talk about just one of them, and that’s β-glucuronidase. References: 1) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/ 2) https://pmc.ncbi.nlm.nih.gov/articles/PMC12942269/ 3) https://pmc.ncbi.nlm.nih.gov/articles/PMC12942269/, https://www.thieme-connect.com/products/ejournals/abstract/10.10...
Improving Your Progesterone to Oestrogen Ratio with Three Simple Steps 25.04.2026 13:15
This week on the podcast I want to do a mini episode on improving your progesterone to oestrogen ratio in the luteal phase. And the reason being is that I track a lot of my client’s hormones with Mira, which is an at home hormone tracker, and I frequently see higher oestrogen levels and lower progesterone levels in the luteal phase. References: 1) https://academic.oup.com/jcem/article-abstract/77/...
Could Your Bloating and Nausea Be Caused By Delayed Gastric Emptying? 17.04.2026 22:26
Today’s episode is a quick but informative one as I have a very packed week of client calls. So, I wanted to do a mini episode on gastroparesis and delayed gastric emptying (stomach emptying) in hEDS and POTS patients, because as you probably know by now if you listen to my show, people with endo have a higher risk of having one or both of these conditions. References: https://pubmed.ncbi.nlm.nih....
SIBO Awareness Day Special: Can Probiotics Treat SIBO? 08.04.2026 33:06
Today I want to talk to you about an alternative SIBO protocol I have been using with clients since last year - and that’s probiotics. I know, controversial, so let’s get started and you’ll learn why I have begun using them. References: https://journals.lww.com/ajg/fulltext/2020/02000/acg_clinical_guideline__small_intestinal_bacterial.9.aspx https://pubmed.ncbi.nlm.nih.gov/28267052/ https://pubme...
The Link Between Pelvic Congestion Syndrome and Endometriosis with Dr Alexis Cutchins 04.04.2026 59:52
Today’s episode is with Dr Alexis Cutchins and we’re talking all about pelvic congestion syndrome (or pelvic venous disease as it’s also known as) and its connection to endometriosis, POTS, MCAS and Hypermobility Spectrum Disorders. Dr Cutchins is a board certified cardiologist with a passion for caring for patients with Postural Orthostatic Tachycardia Syndrome, Mast Cell Activation Syndrome and...
Optimising Fertility with Endo with Dr Lizzie Alexander 28.03.2026 1:09:55
Today’s episode is with Dr Lizzie Alexander (PhD), an Integrative Nutrition Health Coach (who is also currently training as a Naturopath & Nutritionist) specialising in endometriosis and fertility. After 25 years of undiagnosed endo, chronic pain, and her own fertility struggles, Lizzie found healing through working with a naturopath in New Zealand and embracing functional nutrition. She becam...
MCAS 101 - And What It Has to Do With Endo 21.03.2026 25:10
Today I am continuing with my series on the trifecta of POTS, MCAS and h-EDS/hypermobile spectrum disorders and how they are connected to endo, and today we are basically doing a little MCAS 101. Affiliate Partnerships mBIOTA - mBIOTA Elemental is the next generation of the elemental diet and is developed with leading gastroenterologists and food scientists. It’s both clinically effective and easy...
The Latest Research on the Elemental Diet for SIBO with mBiota CEO Nicola Wodlinger 14.03.2026 1:19:42
Today I am talking to Nicola Wodlinger, CEO of mBIOTA, the founders of the mBIOTA Elemental diet, which is a treatment I use with many of my SIBO clients but is also a treatment for other gastrointestinal conditions such as IBS and Crohn’s. The elemental diet is notoriously bad tasting, so the founders of mBIOTA set out to create an elemental diet that was both clinically effective for treating SI...
These Simple Evidenced-Based Strategies Can Actually Lower Your Oxidative Stress Markers with Endo 07.03.2026 18:45
Recently we’ve been talking about oxidative stress and endo, and how it can lead to more inflammation and pain, but also endo growth and earlier perimenopause or ovarian decline. So today, rather than throwing a tonne of strategies at you in one go, I want to offer some simple dietary hacks that can truly increase your antioxidant levels and measurably lower your oxidative stress and inflammation...
Early Perimenopause Changes and Symptoms for Endometriosis Patients 01.03.2026 22:51
Last week I talked about why those of us with endo may be experiencing earlier perimenopause, and why we’re at greater risk of early menopause and Premature Ovarian Insufficiency. This week, in case you’re in this group, I wanted to share what is happening in the first half of perimenopause and the symptoms to look out for, as for us endo peeps, they’re a bit different from the average. Affiliate...
Why People with Endo are at Higher Risk of Early Menopause and Premature Ovarian Insufficiency 20.02.2026 16:07
I wanted to do this episode on perimenopause and menopause because so many clients are in perimenopause or are approaching the age when it begins, and often when they come to me, they have no idea what’s going on and how all these worsened or new symptoms could all be connected to one thing. Affiliate Partnerships DITTO - DITTO is a clinically studied PMS and PMDD supplement with 10 ingredients th...
WTF is Oxidative Stress and What’s Its Role in Endo? 14.02.2026 16:18
Today I want to start a series called ‘WTF is…?’ where we look at the different mechanisms behind endo growth and development so we can understand them better and understand why we may want to focus on endo management changes like diet and lifestyle. Today I want to talk about oxidative stress. Affiliate Partnerships DITTO - DITTO is a clinically studied PMS and PMDD supplement with 10 ingredients...
How to Give Your Diet an Anti-Inflammatory Glow Up Without the Overwhelm 06.02.2026 19:35
Today’s episode is a nice short, and practical episode as I know we’ve been very science heavy lately! I was having a conversation with a client this week, who would like to make some changes to her diet not just for endo, but due to some other health issues which would benefit from leaning towards more of an anti-inflammatory, Mediterranean style of eating. And often, we assume in this day and ag...
POTS and Dysautonomia 101 01.02.2026 20:40
Welcome to our continued series exploring the trifecta of POTS, MCAS and h-EDS/hypermobility, and today we are basically doing a little POTS 101. POTS is a condition caused by a dysfunction of the autonomic nervous system. The autonomic nervous system is the part of our nervous system which governs involuntary actions of the body that essentially keep us alive and we don’t have to think about in...
Study Spotlight: Can Curcumin or Turmeric Reduce Endometriosis Pain? 23.01.2026 23:18
Today we’re kicking off our return to the show after Christmas with our Study Spotlight Series on the study: Dietary Modification and Supplement Use For Endometriosis Pain. And today, we’re looking at the effects of curcumin and turmeric supplementation. I am offering, for January only, £500 off my 1:1 coaching programme, as well as the option of a twelve month payment, so feel free to email me on...
Postural Tachycardia Syndrome Diagnostic Pathway and Criteria 13.12.2025 32:11
I recently did a couple of Instagram carousels about postural tachycardia syndrome or dysautonomia signs and symptoms I see in clients - and the response was absolutely overwhelming, unlike anything I have experienced before (and I’ve had my Instagram for about 12 or so years!). The post has been viewed over 120,000 times and has been saved around 500 times now. This is clearly something so many o...
Study Spotlight: What Is the Research on Dairy and Endometriosis? 06.12.2025 29:34
We’re continuing with our Study Spotlight Series on ‘Dietary Modifications and Supplement Use for Endometriosis’, and today we’re looking at dairy. Affiliate Partnerships DITTO - DITTO is a clinically studied PMS and PMDD supplement with 10 ingredients that target both the mental and physical challenges that come along with the menstrual cycle, developed by a PhD Nutrition Scientist. You can use t...
Study Spotlight: Peppermint for Endometriosis Pain - Can It Help and Why? 30.11.2025 28:05
Today we’re continuing our Study Spotlight Series on the study: Dietary Modification and Supplement Use For Endometriosis Pain. And today, we’re looking at the effects of peppermint supplementation. So first, let’s look at what this study found, that out of those who tried peppermint supplementation, roughly 26% experienced a reduction in pain. Affiliate Partnerships DITTO - DITTO is a clinically ...
Evidence-Based Nutrients for PMS, PMDD, Endo Pain and ADHD, and the Gap Between Nutrition Research and Medicine with Alice van der Schoot of Ditto 22.11.2025 1:05:29
Alice van der Schoot is a PhD nutrition scientist with a background in neuroscience. Her work brings together both fields to explore how nutrition can impact underlying mechanisms of PMS, PMDD, and period pain to reduce symptoms - from neurotransmitter function, to pain processing and inflammation. Recognising that valuable research often remains hidden in academic journals, Alice founded DITTO to...
Study Spotlight: Can Lowering Gluten Intake Improve Pain and Quality of Life with Endometriosis? 14.11.2025 34:05
Today we’re continuing with our Study Spotlight Series on the study Dietary Modification and Supplement Use For Endometriosis Pain. Affiliate Partnerships DITTO - DITTO is a clinically studied PMS and PMDD supplement with 10 ingredients that target both the mental and physical challenges that come along with the menstrual cycle, developed by a PhD Nutrition Scientist. You can use the code: ENDOBEL...
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