Holly Hester-Reilly

The Product Science Podcast

Business EN ↓ 124 episodes

The Product Science Podcast is for startup founders and product leaders building high-growth products, teams, and companies. Listen in on real conversations with the people who have tried it and aren’t afraid to share the lessons they’ve learned (and the mistakes they’ve made) along the way.

Author

Holly Hester-Reilly

Category

Business

Podcast website

productsciencegroup.com

Latest episode

Oct 21, 2025

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Episodes

The Dina Levitan Hypothesis: Systems Thinking Scales Products and Organizations 21.10.2025

With an impressive background in computer science from MIT and years of experience as a site reliability engineer at Google, Dina Levitan shares how she approaches the art of problem definition, and what she’s learned about the value of subject matter expertise versus disciplined product management skills. The episode also touches on Dina’s passion for consulting, her thoughts on work-life integra...

The Mike Belsito Hypothesis: Evidence-Based Product Decisions Require Customer Conversations and Experiments 06.05.2025

What happens when the product science principles are applied to a conference organization?  You get Product Collective, now called Mind The Product by Pendo.io. Through events like INDUSTRY: The Product Conference, along with resources such as a member hub and over 100 hours of past conference videos, product professionals across the globe find community, learn, and improve their work.   Rather th...

The Andy Breen Hypothesis: Testing for Value Risk is the Most Critical Yet Overlooked Piece of Product Success 15.04.2025

Andrew Breen, CEO of Prints of Love and Partner at Buy Build Fund, a seasoned entrepreneur and educator, believes in the power of observing user interactions to uncover the subconscious value people place on products, thereby driving strategic decisions beyond mere spreadsheet analysis. His experience reflects advocacy for addressing often-overlooked value risk and emphasizes the necessity of unde...

The Ha Nguyen Hypothesis: Passion, Commitment, and Community will Drive Your Product Career to New Places 01.04.2025

Ha Nguyen, a seasoned Silicon Valley product leader, then co-founding partner at Spero Ventures, Chief Experiences Officer at Swimply, and now Managing Partner at NextStep, a fractional & advisory COO consulting firm, shares her perspective, lessons learned, and journey through the ranks with us today.   Ha's journey underscores the importance of adaptability, continuous learning, and leve...

The Stephanie Leue Hypothesis: Developing Product Strategy is a Critical, Ongoing Piece of the Chief Product Officer Role 25.03.2025

How do CPOs balance keep teams engaged in meaningful work while building a product strategy from scratch? Stephanie Leue, Chief Product Officer at Doodle at the time of this recording, shares how she integrates customer feedback, collaboration with internal teams, and data-driven insights to inform strategic decisions, underscoring the value of communication and using various artifacts to convey t...

The Hubert Palan Hypothesis: Customer-Centricity and Effective Segmentation are Key to Building a Successful Product Company 18.03.2025

Product management is a complex and multifaceted role that requires a delicate balance of strategy, organization, and communication. In order to effectively manage products from ideation to launch and beyond, product managers need the right tools at their disposal. This is where product management tools come into play.   Hubert Palan, the founder and CEO of Productboard, is a key figure in the evo...

The Inessa Lurye Hypothesis: Successful Product Launches Require Systematically Building and Testing Solutions to Market Opportunities 11.03.2025

Key aspects of product development, such as recognizing a true market opportunity, structuring teams for new market pursuits, and proving ROI when launching a new product are unpacked in this episode with Inessa Lurye as Holly Hester-Reilly's guest.   Inessa Lurye, as the Senior Director of Product and head of Women's Health at Hinge Health, identified a substantial market gap and shares h...

The Melissa Perri and Denise Tilles Hypothesis: Product Operations Provide Infrastructure for High-Quality Product Decision-Making 04.03.2025

Meet Melissa Perri and Denise Tilles, the dynamic duo behind the groundbreaking book “ Product Operations: How Successful Companies Build Better Products at Scale .” Melissa's expertise spans from founding Produx Labs, a product management training and consulting company, to spearheading product strategies at esteemed companies like Insight Partners, Capital One, Vanguard, and Walmart/Sam’s Cl...

Season 6 Announcement & Company Update 14.12.2023

In this mini-episode of the podcast, Holly introduces team members Dina Levitan and Mark Enache, who share some stories about working with Product Science Group clients. Holly also tells us about changes coming for Season 6 of the Product Science Podcast - video, shorter episodes, and a new Lab Notes section. Subscribe for the full episode on  Apple ,  Google Play ,  Spotify ,  YouTube , and more....

Season 5 Highlights: The Product Discovery Loop 13.06.2023

Holly Hester-Reilly is the Founder and CEO of H2R Product Science, a product management coaching and consulting firm that teaches the principles and practices of high-growth product development, and the host of the Product Science Podcast. Holly is a former Columbia University research scientist and has spent over 15 years leading product initiatives at startups, high-growth companies, and enterpr...

The Jeff Patton Hypothesis: Successful Teams Focus on the Who Before the What 30.05.2023

Jeff Patton helps companies adopt a way of working that’s focused on building great products, not just building stuff faster. Jeff blends a mixture of Agile thinking, Lean and Lean Startup Thinking, and UX Design and Design Thinking to end up with a holistic product-centric way of working. Jeff is author of the bestselling O’Reilly book User Story Mapping which describes a simple holistic approach...

The Christian Idiodi Hypothesis: Great Product Management Starts With Admitting “I Don’t Know” 09.05.2023

Christian is a partner at Silicon Valley Product Group. Christian has been a product leader for over 15 years, building teams and developing enterprise and consumer products that have shaped companies such as CareerBuilder and Merrill Corporation as well as clients such as Microsoft, Starbucks, and Squarespace. Christian teaches product management and innovation at Virginia Commonwealth University...

The Peter Voss Hypothesis: We Will Soon Need to Embrace AI to Be Effective in the World 02.05.2023

Peter Voss is a Pioneer in AI who coined the term ‘Artificial General Intelligence’ and the CEO and Chief Scientist at Aigo.ai . For the past 15 years, Voss and his team at Aigo have been perfecting an industry disruptive, highly intelligent and hyper-personalized Chatbot, with a brain, for large enterprise customers. In this episode of the Product Science Podcast, we cover career opportunities in...

The Matt LeMay Hypothesis: Great Product Managers Never Have to Say Yes or No 25.04.2023

Matt LeMay is the author of Product Management in Practice (now in its second edition) and product leader and consultant who has worked with companies like Google, Spotify, Mailchimp, and Audible. In this episode of the Product Science Podcast, we cover how constraints can be helpful in product, the effects of getting promoted without being ready, and why great product managers don’t need to say y...

The Risa Stein Hypothesis: Trust is a Crucial Component of a Successful Product 18.04.2023

Risa Stein is a Director of Product, Integrity leading teams focused on protecting customer safety, privacy, and security. Risa and her team are responsible for setting and enforcing policy, investigating and stopping bad actors who try to abuse Slack, and developing new product features to protect Slack's customers. Prior to joining Slack, she led Transparency and Safety Experience products a...

The Paul Orlando Hypothesis: Great Product Strategy Answers The Why Now Question 11.04.2023

Paul Orlando helps organizations unlock new revenue and partnership opportunities, getting companies to solve problems that they couldn't in other ways. He has built startup programs around the world (Hong Kong, Los Angeles, Rome, and remote). Paul also teaches at the University of Southern California. In this episode of the Product Science Podcast, we cover how to know when to pivot, answerin...

The Nils Davis Hypothesis: A Good Story Comes From Solving A Real Problem For Real People 04.04.2023

Based on more than two decades of enterprise product management experience, including a stint managing a product for product managers, Nils Davis has lots of knowledge and wisdom. In his podcast, the Secrets of Product Management he shares powerful ways for product managers to create more value by ensuring every product is a solution to a meaningful market problem. And that every team creating and...

The Andrew Skotzko Hypothesis: If You're Going to Try and Change Somebody's Behavior, You Better Understand It 28.03.2023

Andrew Skotzko is a product discovery & strategy advisor to tech companies who has built products and led teams for 13 years. By day, he advises companies on product leadership & strategy to make products which find traction in the market and help people thrive in the process. By night, he picks up the mic on his podcast,  Make Things That Matter , and explores how product innovation, cogn...

The Dean Peters Hypothesis: The Best Products Are Created From Problem-Focused Conversations 21.03.2023

Driven by a passion to replace pain points with user delight, Dean Peters has provided product management expertise across a variety of domains and technologies for nearly two decades. From large enterprises such as IQVIA and Citrix to startups such as Dude Solutions and Seven Lakes Technologies, to merged and acquired companies such as Aprimo and McClatchy, Dean has helped teams self-organize, an...

The Roman Pichler Hypothesis: Establishing an Effective Agile Product Management Organization Takes Time 14.03.2023

Roman Pichler is a leading product management expert specialized in product strategy, leadership, and agility. He has advised product leaders and he has taught product managers and product owners for more than 15 years. Roman has pioneered agile product management practices, and he has developed a range of models, methods, and tools to help organizations create successful products. Roman shares hi...

The Andrew Michael Hypothesis: Mixing Qualitative and Quantitative Research Methods Leads to Better Product Decisions 28.02.2023

Andrew Michael is an entrepreneur with 14 years of experience in digital growth companies as a founder or senior manager with a focus on customer retention, data analytics, product, and growth. In this episode of the Product Science Podcast, we cover the mistakes Andrew made early on in his startup career and at what points in the development process he focuses on quantitative vs qualitative resea...

The Lisa Marie Zane Hypothesis: Conscious Product Development is Building a Better Future For Tech 21.02.2023

Lisa is the Founder of Conscious Product Development. Her purpose is to help product teams solve the right problems for the right reasons and develop products (and careers) more consciously - in ways that are inclusive, holistic, ethical, accessible, and sustainable - and that makes people's lives measurably better. She previously worked at Google, several wearable tech startups, and with Bauer Ho...

The Shane Zilinskas Hypothesis: User Research and Empathy Drive Products From 0 to 1 14.02.2023

Shane Zilinskas has worked on many product launches for companies ranging from startups to Fortune 500. He started off as an engineer before finding his way to product management, when a book and a one-way ticket to Europe led him, together with his wife Kara McGehee, to build ClearSummit, an agency that has helped 100s of companies take their products from 0 to 1. In this episode of the Product S...

The Christina Xu Hypothesis: Accessibility is a Critical Aspect of Product Design 07.02.2023

Christina is a product manager at Slack, focused primarily on improving the accessibility of both Slack and Quip (the collaboration tool, not the toothbrush company!) for people with disabilities. Previously to working in product, Christina was an ethnographer focused on how people incorporate technology into their lives, with over a decade of experience in observing and orchestrating social inter...

The Jason Keramidas Hypothesis: With Enterprise Products, the Sales Team is Your Biggest Asset 31.01.2023

Jason Keramidas is always thinking about how to build products that will make people’s lives better. He has over 25 years experience working with a range of companies from early stage startups to driving growth at public companies. He lives just north of NYC with his wife and two children. In this episode of the Product Science Podcast, we cover Jason’s early days in product management, what is di...

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