The NewsWomb

*TRIGGER WARNING* this episode discusses stillbirth, infant loss, and fetal loss and may be distressing or trigger for some listeners. Listener discretion is advised. In this episode of Debunking Dramatizations we’re going to talk briefly about House of the Dragon Season 1 Episode 10 – The Black Queen. This is the fourth. Yes, the FOURTH obstetrical delivery depicted in just this one season of Hou...

The cherry on top of our season on HDFN and alloimmunization. This week we're talking about the future potential medical therapies for this disease including nipocalimab. See below for the episode outline and topics Dr. Moise discusses this week! The neonatal Fc receptor is the FcRN (Neonatal crystallizable fragrant receptor) Where FcRN receptors are located in the human body Endothelial cell...

In this episode we’re going to discuss future pregnancy & conception options after alloimmunization sensitization. Dr. Moise starts by briefly touching on Bethany Weathersby’s story after her loss to HDFN and her pregnancies that followed. Bethany is the mother of five living children, the CEO and founder of The Allo Hope Foundation , and one of the hosts of The Allo Podcast . about her pregna...

Bili is back and so is Dr. Lopriore! Last week we talked about Phase 1 of neonatal management of HDFN and alloimmunization. This week we’re moving into Phase 2 while we discuss the following: Phase 1: intensive phototherapy – usually lasts about 1-2 weeks Phase 2: monitoring neonatal hemoglobin & hematocrit Outpatient neonatal monitoring – measuring hemoglobin, hematocrit, and reticulocyte cou...

Special guest on our episode this week and next, Dr. Enrico Lopriore from Leiden University. He sat down with us at IFMSS in November to do a special episode on the neonatal portion of alloimmunization and HDFN.  This week we start by discussing Dr. Lopriore's background and training and then cover treatment and management of HDFN in the neonatal phase. See below for more details! Hyperbiliru...

This week we're going to summarize all the tools we've discussed for alloimmunization and HDFN. We’re going to use case scenarios to walk through the individual diagnosis, management, surveillance, and treatment, followed by delivery and the neonatal course for each. Dr. Moise takes us through three different case scenarios - mild, moderate, and severe. See below for timestamps and some...

Bring the caffeine as we wrap up IUTs this week with our detailed step by step on the procedure itself. In this episode we talk about: The pre-operative process including consenting and lab studies Using the MCV value on a CBC to determine fetal vs. maternal sample (only works for the 1st IUT)  Fetal sample= 105-110 Maternal sample = 80s-90s How much blood to order from the blood bank for a transf...

Grab your coffee and eat your Wheaties wombmates! We’ve finally made it to our favorite topic – Intrauterine Transfusions! We love this topic so much we had to split it into two parts to cover everything we wanted to. This week we'll cover the background and leading up the procedure itself, then next week we'll go into more detail about the procedure itself. See the topic list below for...

Breaking into our toolbox this week! Dr. Moise takes us through immune therapy options in the treatment and management of HDFN and alloimmunization. This week we cover the following topics: Alloimmunized patients that qualify for immune therapy as management for HDFN Options available for immune therapy Intravenous immunoglobulin (IVIG) Plasmapheresis Timing, dosing, frequency, and administration...

A brief little bonus episode of Erin's interview with Dr. Michael Harrison while at the 40th annual IFMSS conference in Los Cabos in early November 2022.  Many consider Dr. Michael Harrison to be the Father of Fetal Surgery. He paved the way for many of the advancements we know today in fetal medicine and has continued his work as a professor of pediatric surgery and director emeritus of the...

This week we're going into a deep dive on MCA Doppler as Dr. Moise discusses the following:  The initial role & importance of ultrasound in pregnancy – determining crown rump length (CRL) to then calculate the estimated date of delivery (EDD) How MCA Doppler was first discovered – thanks to Dr. Gian Carlo Mari How viscosity and cardiac output are affected in an anemic fetus MCA Doppler pe...

Earlier this month we jetted off to Los Cabos, Mexico to attend the 40th annual the International Fetal Medicine and Surgery Society (IFMSS) conference. This is the first time the society has been able to meet since COVID-19 and with that came a lot of new research and exciting advancements in the field of fetal medicine. Dr. Moise takes us through his top 11 topics from this jampacked conference....

Financial Disclosure: Dr. Moise receives fees paid on his behalf to Dell Medical School - UT Austin for consultation with the genetics company BillionToOne, Inc. This week we're trekking on through more details about alloimmunization and HDFN in the setting of lab studies and specific testing. Dr. Moise discusses the timing intervals for maternal antibody screenings, defines a critical titer,...

We're kicking off the holiday season early this year courtesy of the mneumonic 'DEcK' that stands for the major HDFN red blood cell antigens 'bad players' - D, big E, little c, and Kell. This week Dr. Moise talks about some of the more common red cell antigens and also the not so common. We wrap up our discussion on antigens using a dalmation analogy to help describe weak...

Happy Halloween wombmates! Our special spooky gift to you is another segment of "Debunking Dramatizations". Dr. Moise is a diehard Game of Thrones fan and so naturally has closely followed the new House of the Dragon series on HBOMax. In this episode, Dr. Moise walks us through the series premiere episode, "The Heirs of the Dragon", in which Queen Aemma's attempts to deliv...

Dr. Moise teaches us about rhesus immune globulin, how it's made, when to administer it, and how it played in a role in university mens' income.

Part 2 of 2 continues our discussion on the history of Rh disease. Dr. Moise talks about how the diagnosis and treatment of this disease have changed over the years. We also discuss the major contributions to this disease by Sir William Liley. Dr. Giancarlo Mari, Dr. Dennis Low, Dr. Charles Rodeck, and many others. Giancarlo M., et al. Noninvasive Diagnosis by Doppler Ultrasonography of Fetal Anem...

Part 1 of 2 covering the history of Rh disease. Dr. Moise talks about the history of the disease itself and the history of prevention. We discuss how the Rh antigen was first discovered. And then we cover how RhoGAM (AKA rhesus immune globulin) was first developed and the experiments designed to determine the intervals to administer the medication in a patient's prenatal and delivery course. ...

Remember that comedic relief we promised? In this episode, Dr. Moise and Erin discuss a fetal surgery case from NBC's series New Amsterdam Season 4 Episode 20 "Rise". 

We start every fetal surgery in the operating room with a timeout. Dr. Moise always asks we begin with introductions starting at the head of the bed. This episode we'll be introducing ourselves and how we got to where we are today.  The first half tells Erin's story and background. 21:36 begins Dr. Moise's story and background.

Each week, Dr. Kenneth Moise and his daughter, Erin Moise, bring the latest in the field of fetal medicine by delving into the history, background, diagnosis, and treatment of complex fetal conditions.