The mTOR You Know

What does it actually look like to transition from a specialized clinical role in transplantation to a career in the pharmaceutical industry? In part 2 of this "couch session" episode, host Aileen Chi sits down with industry veterans Drs. John Lyons, Simon Tremblay, and Tim Horwedel will examine the learnings in their career transitions. Tune in for an engaging and candid discussion on h...

Join Lauren Richey, PGY2 Solid Organ Transplant Pharmacy Resident at UCSF, as she reviews CMV prevention strategies in high-risk liver transplant recipients. This episode highlights the CAPSAL trial comparing antiviral prophylaxis and preemptive therapy in CMV D+/R− recipients, reviews key updates from the 2025 International CMV Consensus Guidelines, and discusses practical implications for transp...

After a long day of "left brain" science and analytics, how do you let your "right brain" take over and unleash your creativity? Transplant pharmacists Alicia Lichvar and Stacy Fredrick join hosts Lauren Schumacher, Kimberly Leale, and Brooke Aston to discuss their awesome artistic passions. From yarn crafts, to cooking, to photography, and more, we discuss how these creative a...

PGY2 SOT Gillian Stiger joins us from the Hospital of the University of Pennsylvania to discuss “Clazakizumab in the treatment of chronic active antibody-mediated kidney transplant rejection: Results from the IMAGINE phase 3, randomized, double-blind, placebo-controlled study”, as well as a discussion on her residency experience with belatacept rapid conversion for a patient with thrombotic microa...

PGY2 Solid Organ Transplant Resident Laura Ramirez joins us from UAB Medicine to discuss “Impact of kidney function on 200 days of antiviral prophylaxis for cytomegalovirus disease in cytomegalovirus- seronegative recipients of cytomegalovirus-seropositive donor kidneys: Post hoc analysis of a randomized, phase 3 trial of letermovir vs valganciclovir prophylaxis”

Leah Georgiades, a current PGY2 SOT at UPMC Presbyterian, discusses “The association between glucagon-like peptide 1 receptor agonists therapy and outcomes after heart transplant” as well as her investigation into drug-drug interactions between letermovir and azole antifungals.

What does it actually look like to transition from a specialized clinical role in transplantation to a career in the pharmaceutical industry? In this "couch session" episode, host Aileen Chi sits down with industry veterans Drs. John Lyons, Simon Tremblay, and Tim Horwedel to pull back the curtain on the journey from the clinic to the corporate world. Tune in for an engaging and candid d...

Meet the award-winning pharmacists advancing transplant care. In this episode, we explore the innovation and clinical excellence recognized by the ACCP Transplant PRN and ACCP Foundation. 00:42 – Annual Meeting Travel Award (Resident): Eleni Pikounis 08:04 – Annual Meeting Travel Award (Pharmacist): Dawn Pluckrose 13:20 – Innovative Fund Award: William Baker 19:05 – Research Award: Abbie Leino 28:...

PGY2 Solid Organ Transplant resident Caroline Simko joins us from the University of Colorado Hospital to discuss “Low-Dose Valganciclovir for Primary Cytomegalovirus Prophylaxis After Heart Transplant: A 10-Year Experience,” along with reflections on her clinical experience counseling identical twins undergoing living donor transplantation without maintenance immunosuppression.

In this episode of mTOR You Know , we share leadership and committee updates from the Transplant PRN business meeting held at the ACCP Annual Meeting in October 2025. Hear from PRN leadership and committee representatives as they reflect on 2025 and outline priorities for 2026.

PGY2 SOT Allyson DeMarco joins us from NewYork-Presbyterian to discuss “Safety of Immunotherapy After Liver Transplantation – A Multicenter Study of a Prospective Standardized Clinical Practice Protocol” (Liver Transplantation 2025), as well as her residency experience managing drug interactions between DOACs and common post-transplant medications.

PGY2 SOT Brooke Aston joins us from the University of Cincinnati Medical Center to discuss “Belatacept Maintenance Immunosuppression for Calcineurin Inhibitor Sparing or Avoidance in Pancreas Transplant Recipients With Progressive Renal or Renal Allograft Dysfunction” (Clinical Transplantation, 2025), as well as her residency experience shadowing in the HLA laboratory to gain firsthand insight int...

For over a decade, the HIV Organ Policy Equity (HOPE) Act has paved the way for transplant centers to accept organs from patients with positive HIV tests for transplant into recipients living with HIV under the research protocol. Earlier this year, following many years of positive outcomes, policy was updated to allow kidney and liver transplant centers to perform these transplants without the nee...

Whether you are interviewing for a PGY1, PGY2, or clinical specialist position, you will want to listen to this jam-packed episode of advice from panelists who have experience conduction interviews for all of these positions! Transplant clinical specialists, Drs. Nick Parrish and Rickey Evans, join hosts Lauren, Kim, and Stephanie to discuss anything and everything you have wanted to know about pu...

In this episode of The mTOR You Know , we dive into the evolving role of pharmacogenomics in solid organ transplantation with a focus on tacrolimus andCYP3A5. Our expert panel—Jennifer Trofe, Amy Pasternak, and Shirley Tsunoda—share insights on clinical trial data, guideline perspectives, and real-world application of genotype-guided dosing. We explore the benefits and limitations of CYP3A5 testin...

In case you missed the live event or would like to revisit the discussion, we are bringing you another opportunity to tune in here! Join moderators Dr. Emily Sartain and Dr. Barrett Crowther as they chat with panelists Dr. Dawn Pluckrose, Dr. Idris Yakubu, Dr. Kayla Joyal, and Dr. Lyndsey Bowman Anger on Mentorship Tips and Tricks. Thank you to the ACCP Txp PRN Programming Committee and the AST Ph...

We’re back with Part 2 of our CMV series! Hosts Aileen Chi and Xena Huang return with the expert panel from the University of Wisconsin—Margaret Jorgenson, Jillian Fose, and Hanna Kleiboeker—to continue the conversation on CMV management in cardiothoracic transplant. In this episode, we explore tricky real-world cases, discuss strategies for managing antiviral resistance, and learn how this team b...

In this episode, we’re bringing you the audio from a recent ACCP joint webinar hosted by the Cardiology and Transplant PRNs—featuring pharmacist-curated highlights from the 2025 ISHLT meeting! Join Dr. Ian Hollis (UNC Health), Dr. YeeAnn Chen (University of Rochester Medical Center), and Dr. Xena Huang (NewYork-Presbyterian/Columbia) as they break down key takeaways in mechanical circulatory suppo...

Staying ahead of CMV is crucial for cardiothoracic transplant patients. In this episode, the first of a two-part series, hosts Aileen Chi and Xena Huang welcome a panel of experts from the University of Wisconsin: Dr. Margaret Jorgenson, Dr. Jillian Fose, and Dr. Hanna Kleiboeker. Join us as we delve into the complexities of CMV monitoring and management in this high-risk patient population. Our g...

Join PGY2 SOT Pharmacy Resident Melissa Vu Maffei to discuss “The impact of sodium-glucose cotransporter-2 inhibitors on dialysis risk and mortality in kidney transplant patients with diabetes.”

PGY2 SOT Brittany Huynh joins us from the University of California, San Diego Health to discuss “Evaluation of lipid management practices for secondary atherosclerotic cardiovascular disease prevention in abdominal solid organ transplant recipients”

PGY2 SOT Kylea Clark joins us from the University of Alabama at Birmingham to discuss “Insights from the BKEVER Trial comparing everolimus versus mycophenolate mofetil for BK Polyomavirus infection in kidney transplant recipients.”

Transplant surgeons Dr. Manish Gupta and Dr. Garrett Roll chat with hosts Aileen Chi and Kimberly Leale on this exciting multidisciplinary episode of The mTOR You Know. Join us as we learn amazing insight about new surgical technology and its impacts on immunosuppression, outcomes, and the global transplant ecosystem. You're going to want popcorn for this one!

PGY2 SOT pharmacy resident Daniela Barisano joins us from Children’s Healthcare of Atlanta to discuss “Influenza Vaccine Coverage and Effectiveness for the 2022-2023 Respiratory Season in Pediatric Solid Organ Transplant Recipients,” as well as share her experience from participating in the outpatient adolescent kidney, liver, and heart transplant clinics.

PGY2 SOT resident Courtney Hooten from UW Health in Madison, WI, joins us to present "Effects of SGLT2 Inhibitors on Transplant Survival and Key Clinical Outcomes in Heart Transplant Recipients with Diabetes."