The Lancet Infectious Diseases in conversation with

Dr Brecht Ingelbeen and Dr Daniel Valia join Senior Editor Phoebe Hall to discuss a new trial in the journal (the CABU-EICO trial) testing a co-created behavioural intervention bundle to improve antibiotic use, patient management, and water, sanitation and hygiene in rural communities in Burkina Faso and DR Congo. They explain why the study focused on community prescribing (not hospitals), the pri...

Sara Tartof and Matan Yechezkel discuss a new article in The Lancet Infectious Diseases about emerging doxycycline resistance against gonorrhoea and its wider implications for the implementation of doxycycline and the prevention of bacterial sexually transmitted infections. Click here to read the full article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00123-4/fulltext The...

Dr Jenny Clarke and Herve Semukunzi discuss a study they and colleagues recently published with us  titled ‘Infection- and vaccine-induced mpox antibodies: validation of a combined mpox IgG ELISA during the clade 1b outbreak in Rwanda’.  They also discuss the reasons for the paucity of validated serological assays for mpox, particularly in outbreak regions where they are most urgently needed.  Cli...

Dr Julia Moore Vogel and Dr Danilo Buonsenso discuss various aspects of long COVID including epidemiology, pathophysiology, underlying mechanisms, management, latest research developments, difficulties in conducting clinical trials, and future research priorities. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https:/...

Professors Steven Tong and Joshua Davis discuss all aspects of adaptive platform trials including advantages, disadvantages, differences from conventional trials, and tips for setting up and assessing them. They also highlight several adaptive platform trials currently in the pipeline that could influence infectious disease clinical practise in the future. Click here to read our latest issue Conti...

Professor Ana Odone, Dr Jesus Rodriguez-Manzano, and Dr Alex Howard discuss their new Series of papers on artificial intelligence and infectious diseases intended to support the infectious diseases community in understanding this evolving landscape and in actively shaping artificial intelligence integration into practice. Read the full Series here: https://www.thelancet.com/series-do/artificial-in...

Drs Catherine Liu and Joshua Hill of the Fred Hutchinson Cancer Center discuss their new Series of papers on the prevention and management of infections in people who are immunocompromised, with a focus on prevention of infections and diagnostic and antimicrobial stewardship. Read the Series papers: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00345-7/fulltext?dgcid=buzzsprou...

Lilian Tina Minja and Norbert Heinrich discuss the SUDUCO and DECODE trials in The Lancet Infectious Diseases on two new promising TB drugs, sutezolid and delpazolid, respectively. They also discuss the wider implications of the findings of these trials for TB drug development and treatment. Read the trials: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00213-0/fulltext?dgcid=...

Leonardo Basso and Juan Pablo Torres discuss their study in The Lancet Infectious Diseases on the effectiveness and impact of the first season of Chile's national immunisation programme with nirsevimab. They discuss the evidence that led to the design and implementation of the programme, its impact on RSV burden and the Chilean health system, and lessons for other countries in the region and beyon...

Jan Felix Drexler and Fernando Bozza discuss their recent study published in the journal— “The spatio-temporal ecology of Oropouche virus: a laboratory-based modelling study across Latin America” and its wider implications for Oropouche virus and other arboviruses transmission, expansion, surveillance, and control. Read the full article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3...

Prasad Kulkarni discusses a new Phase I trial in The Lancet Infectious Diseases on a dengue monoclonal antibody also known as VIS513 in healthy adults. In addition, he highlights the wider implications of this for dengue control and drug development. Read the full article: https://www.thelancet.com/journals/laninf/article/ S1473-3099(24)00030-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_laninf...

Oriol Mitjà discusses a new trial in The Lancet Infectious Diseases on the use of oral linezolid compared with benzathine penicillin G for the treatment of early syphilis in adults. He also highlights what the trial means for treatment of syphilis. Read the full article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00683-7/fulltext?dgcid=buzzsprout_icw_podcast_generic_laninf...

Sofia Viegas and Stefan Niemann discuss a new article in The Lancet Infectious Diseases about emerging bedaquiline resistance in Mozambique and its implications for drug resistant tuberculosis and the fight to end tuberculosis. Read the full article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00498-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_laninf Continue this convers...

Luciano Moreira and Henrik Salje discuss a new article in The Lancet Infectious Diseases describing the use of the Wolbachia bacteria to control the spread of mosquito-borne dengue and chikungunya in Rio de Janeiro, Brazil. Read the full article: Estimating the effect of the wMel release programme on the incidence of dengue and chikungunya in Rio de Janeiro, Brazil Continue this conversation on so...

Richard Maude discusses a new article in The Lancet Infectious Diseases that assesses the efficacy of malaria chemoprophylaxis among forest goers in Cambodia. Read the full article: Antimalarial chemoprophylaxis for forest goers in southeast Asia Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thel...

Ben Cowling discusses a new article in The Lancet Infectious Diseases describing the protection that vaccines are providing against COVID-19 in Hong Kong. Read the full article: Vaccine effectiveness of one, two, and three doses of BNT162b2 and CoronaVac against COVID-19 in Hong Kong Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/th...

Hugh Adler discusses a new article in The Lancet Infectious Diseases describing the management and the clinical features for seven patients with monkeypox hospitalised in the UK between 2018 and 2021. Read the full article: Clinical features and management of human monkeypox: a retrospective observational study in the UK Continue this conversation on social! Follow us today at... https://thelancet...

Prof Beate Kampmann, Dr Karen Keddy, and Prof Peter Ghazal discuss a new cross-journal Series in The Lancet Infectious Diseases and EBioMedicine addressing the potential for and challenge of applying big data to childhood infectious diseases in LMICs. Read the full Series: https://www.thelancet.com/series/big-data-childhood-infections-LMICs   Continue this conversation on social! Follow us today a...

A new article highlights how changing immunity profiles motivate the need for better responses to outbreaks of polio in Africa. Read the full article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00453-9/fulltext Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedical...

Paul Chapman and colleagues presents the results of an innovative trial assessing the safety of vaccinating healthy volunteers with attenuated Necator americanus hookworm larvae.  Read the full article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00153-5/fulltext Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/...

Josep Llibre discusses a trial on the impact of same-day testing for SARS-CoV-2 infection before a concert on new COVID-19 cases in Barcelona, Spain. Read the full article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00268-1/fulltext Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://faceboo...

Yap Boum (MSF) discusses his study done in Cameroon, which developed a promising testing strategy for COVID-19 to optimise the available resources. Read the full article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00132-8/fulltext Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook....