Dave Asprey

The Human Upgrade: Biohacking for Longevity & Performance

Health EN ↓ 1554 episodes

For more than a decade,  Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee -  has redefined what’s possible for the human mind and body. After more than a thousand episodes of  Bulletproof Radio , he’s taking it to the next level with  The Human Upgrade™  - a masterclass in  biohacking, longevity, and performance optimization. Each episode explores  cutting-edge science, advanced technology, and proven biohacks  to help you  upgrade your energy, focus, metabolism, and resilience.  You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakth...

Author

Dave Asprey

Category

Health

Podcast website

daveasprey.com

Latest episode

Jul 10, 2026

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Episodes

Upgrade Spotlight: Breathe Better, Snore Less & Wake Up With Energy – Mute/Rhinomed : 1028 03.03.2023

Mute  sponsored this episode. In this "Upgrade Spotlight" Episode of The Human Upgrade™... you’re getting the latest knowledge about innovative biohacking tools and technologies that allow you to change your biology and the environment around you.  CEO Michael Johnson joins the show from the Rhinomed headquarters near Melbourne, Australia. Rhinomed, the company behind Mute , pioneers the...

Why Your Mind Works the Way That It Does – Paul Bloom : 1027 02.03.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... a look into the story of the human mind wonders if you’re just a machine made of meat. Guest Paul Bloom, a researcher, teacher and author, studies adult and child development in terms of how people make sense of the world. It turns out that there are all kinds of automated systems in your body that are making sense of the...

How to Challenge Outdated Beliefs About Aging – Steven Kotler : 1026 28.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... you will learn about the beliefs that kick in as normal humans age and most importantly, you will learn what you can do about those limiting beliefs. And who better to discuss this than the author of the book, " Gnar Country: Growing Old, Staying Rad ," Steven Kotler.  Steven is a friend of the show, executive director of the Flow Research Collective,...

Wired to Lead the Neobiological Revolution – Jane Metcalfe : 1025 24.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… the guest is one of the founders of Wired Magazine and someone who has been a continuous source of interest, news and data for decades, Jane Metcalfe. Having basically dissected nerds for her entire life, Jane now runs a fantastic newsletter and news site called NEO.LIFE where she writes about biohacking and the future. If you were to combine someone who real...

Dave Asprey Shares All Things “Smarter Not Harder” – Interviewed by Rich Diviney : 1024 23.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... to celebrate the imminent release of the new book, we’re doing something different than what you're used to. Dave is getting interviewed on his own podcast to give you a preview of his book, Smarter Not Harder . In the interviewer's seat is retired Navy SEAL commander, author, expert in leadership and human performance, Rich Diviney. When Rich was a guest o...

Acknowledge Your Limits and Get Your Brain Back – A 'Smarter Not Harder' Intervention – Cindy Fraley : 1023 21.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... Dave talks with Cindy Fraley, who has a young daughter, works in upper-level management at a large pharmaceutical company, and is a former physical therapist who overcame RA, MRSA, Hashimoto’s and emotional stress.  Cindy says, “Dave’s guidance, the Upgraded Collective, and biohacking have been pivotal in my journey back to the great health, sports, an...

How to Become a Durable Super-Dad – A 'Smarter Not Harder' Intervention – Bryan Gardner : 1022 16.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... Dave talks with Bryan Gardner (a self proclaimed “super-dad”) who wants to take his current hacking to the next level. Bryan has questions specifically about his brain & neurology, his fitness, and spirituality.  Bryan is an aerospace engineer who built a small hedge fund business more than a decade ago. So he doesn’t sound like someone who would b...

Hacking Your Spirituality - A 'Smarter Not Harder' Intervention - Mandy Pennington : 1021 14.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... Dave talks with Mandy Pennington, a longtime Upgrade Collective member and dedicated hacker who has used biohacking techniques successfully to upgrade her body and mind. Mandy is a sharp and curious person who wants to learn more about how to apply the topics in Smarter Not Harder to her spirituality, quantum energy, spirit guides, and leading a purpose-dri...

Is Remaining Curious the Key to Life, Science and Everything? – Gurudev Sri Sri Ravi Shankar : 1020 09.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... I am honored and grateful to bring you a conversation that I recorded in person with Gurudev Sri Sri Ravi Shankar at the Art of Living Center in Los Angeles.  Gurudev Sri Sri Ravi Shankar is a leader of an international movement with more than 50 million followers who do breathwork every single morning. He has worked for 40 years as a global ambassador...

Exploring Human Potential, Sciencing Spirituality, and Getting Intense – Danica Patrick Interviews Dave Asprey : 1019 07.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™... I do something different. Over the past 1000+ episodes, I have spent a lot of time talking and learning from my guests, but I have heard over and over that you would like to hear more from me about what I am doing, trying and thinking. Well, that can be awkward to do sitting alone in front of a microphone.  A while ago, Danica Patrick interviewed me an...

Upgrade Spotlight: Connecting Ketones, Metabolism & Energy – H.V.M.N. : 1018 04.02.2023

H.V.M.N.  sponsored this episode. IN THIS “UPGRADE SPOTLIGHT” EPISODE OF THE HUMAN UPGRADE ™…Metabolic biochemist Latt Mansor, Ph. D., joins the show from H.V.M.N . (Health Via Modern Nutrition), where he leads research for the company. He’s an expert in metabolism who consults with elite sport, military, clinical and research organizations.  As a key biomarker of metabolic health, keton...

How to Reclaim Feminine Divine Power – Kelly Brogan, M.D : 1017 03.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™ …  Dr. Kelly Brogan  shares why her views often go against conventional thinking—on topics from pharmaceuticals to sex to pole dancing to relationship compatibility.  She's a psychiatrist who specializes in psychosomatic medicine and integrative holistic medicine. Her root-cause resolution approach to psychiatric syndromes and symptoms coup...

Biohacking for Women: How to Capture Your ‘Spark Factor’ – Molly Maloof, M.D. : 1016 01.02.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’re going to learn how to work with your own biology, adapt to adversity, and get resilient AF. Doctor, educator and entrepreneur Dr. Molly Maloof joins the show in person in Austin, Texas, to talk about her debut book, “ The Spark Factor: The Secret to Supercharging Energy, Becoming Resilient, and Feeling Better Than Ever .”  For women biohacker...

Menopause: What to Know, What to Ask & What to Do – Mary Claire Haver, M.D. : 1015 27.01.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… board-certified OB/GYN and “menopause warrior”  Mary Claire Haver, M.D. , joins the show to give women a toolkit to manage what comes before, during and after menopause. She explains the science of women’s hormones, physiology and brain during the menopausal transition. She breaks down the studies, risks, and age timing of Hormone Replacement T...

How to Stack Cold Water, Sauna and Breathing to Accelerate Your Metabolism – Susanna Soeberg, Ph.D. : 1014 25.01.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Susanna Soeberg, Ph. D., a Danish researcher, international scientist and expert in cold and heat therapy for health and performance, explains how you can harness the massive benefits of cold water immersion (winter swimming), sauna, breathing, and your metabolism. When it comes to biohacking, a few things rise to the top and make a pretty big difference...

How Quantum Energy Raises Your Biohacking to a New Level – Philipp Samor von Holtzendorff-Fehling : 1013 20.01.2023

Leela Quantum Tech  sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn why energy frequencies have such a powerful influence on human physiology. Skeptics take note: science backs this up. Philipp Samor Von Holtzendorff-Fehling introduced quantum energy on episode  #809  and its benefits on body function, cellular voltage and chakra energy. He returns t...

How Your Mitochondria Control Your Brain Energy – Chris Palmer, M.D. : 1012 18.01.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Harvard psychiatrist, researcher and assistant professor Christopher Palmer, M.D., introduces a bold new premise about the root cause of mental illness based on decades of research. Dr. Palmer integrated existing theories and research into one  unifying  theory—the brain energy theory of mental illness that’s rooted in your metabolism. Through his r...

Attention Span: How It’s Getting Lost & How to Get it Back – Gloria Mark, Ph.D. : 1011 13.01.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll meet Gloria Mark, Ph. D., who studies how digital media impacts people's lives. Her research specifically covers how attention is affected by, and has changed, with the rise of the digital age. She’s found that attention span now averages 47 seconds on a screen—and even that’s shrinking. As a Chancellor’s Professor of Informatics at the University of C...

Change Absolutely Everything With One Hack – Robert Waldinger, M.D. : 1010 10.01.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™…  you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people  thrive . Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering w...

Upgrade Spotlight: How to Fight Zombie Cells and Win Aging – Neurohacker Collective : 1009 07.01.2023

Neurohacker Collective  sponsored this episode. IN THIS "UPGRADE SPOTLIGHT" EPISODE OF THE HUMAN UPGRADE ™… you’re going to learn about the zombie cells taking up valuable space in your body and how you can clear them out with senolytics. When these zombie cells accumulate (formally called senescent cells), they negatively impact how you age. You may experience symptoms like joint discomfort,...

Sync Your Body & Mind for a More Vibrant Life – Legacy Upgrade ft. Dr. Andrew Weil : 1008 06.01.2023

IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... the new year starts off with a Legacy Upgrade conversation between Dave Asprey and  Dr. Andrew Weil  recorded live at  True Food Kitchen  in Phoenix, Arizona.  Dr. Weil’s an internationally known pioneer and leader in integrative medicine. He’s also a Harvard-trained botanist and medical doctor recognized worldwide for his views o...

How to Simplify Your Intentions and Realize Love – Humble the Poet : 1007 04.01.2023

IN THIS EPISODE OF THE HUMAN UPGRADE™… Humble The Poet joins the show to talk about a unique perspective on love. You’ll learn: what “real” love means (hint: it’s not found or earned) and how to recognize it in your life.  how to shift away from a mindset of earning more, achieving more, and gaining more attention so you can clear pathways for love to enter and flourish in your life how to di...

Upgrade Your Energy – Ari Whitten – Best of 2022 30.12.2022

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… …  Ari Whitten, Ph. D. (Cand.), CES, PES , explains how to double your energy through improved resilience, cell defense, nutrition and supplementation.   In his newest book, “ EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy ,” Ari explains that 5.4 millio...

Upgrade Your Keto Thinking – Steven Gundry, M.D. – Best of 2022 28.12.2022

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… …  Steven Gundry, M.D. , explains that ketones aren’t the fat-burning molecules you think they are. Ketones actually work to enhance health, weight loss, and longevity by acting as signaling molecules that stimulate your mitochondria. A cellular process known as “mitochondrial uncoupling” happens.  He debunks common myt...

Upgrade Your Eyesight – Claudia Muehlenweg – Best of 2022 23.12.2022

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™ … natural vision expert  Claudia Muehlenweg  explains how you can take better care of your eyes and improve your vision.  Her work is based in the  Bates Method . She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually can make eyesigh...

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