The Deep Six

This week on The Deep Six, Dr. Lewerenz sits down with Longevity Health Institute physician Dr. Ryan Abboud for a wide-ranging conversation covering three things most doctors never have enough time to talk about. They break down the CIMT test, a simple in-office ultrasound that can detect soft plaque in your arteries years before a calcium score or standard Doppler ever would, and why that window...

This week on The Deep Six, Dr. Lewerenz welcomes one of his closest mentors, Pastor Dominic Russo of Oakland Church in Rochester, Michigan, for a conversation about faith, community, and spiritual connection. Harvard research links regular church attendance to a 30% reduction in mortality, a 30% drop in depression rates, and a fivefold decreased likelihood of suicide. The NIH has compared the heal...

This week on The Deep Six, Dr. James Lewerenz sits down with Dr. Monica Buchanan, Field Medical Director for the Galleri test by GRAIL, to explore one of the most powerful shifts happening in modern medicine: multi cancer early detection. Dr. Lewerenz opens with a sobering reality: cancer is on the rise in younger populations  and may soon surpass cardiovascular disease as the leading cause of dea...

This week on The Deep Six, Dr. Lewerenz sits down with Matt VanSumeren, PhD candidate and owner of Xceleration Fitness in Auburn Hills, to dig into something most people avoid: actually measuring how fit they are. Matt breaks down what a DEXA scan reveals beyond just body fat, why lower body muscle mass and power are the most overlooked deficiencies he sees, and how visceral fat shows up in unexpe...

This week on The Deep Six, Dr. Lewerenz sits down with Neil King, founder of Neil King Physical Therapy, a Metro Detroit institution with 10 locations and over 65,000 patients served across 30 years. Neil came to physical therapy through an unlikely path in competitive cycling, and that background shapes everything about how he treats patients today. Together, they dig into the real cause of most...

This week on The Deep Six, Dr. Lewerenz trades listener questions for medical journals, pulling from recent issues of the New England Journal of Medicine and The Journal of the American Medical Association to share what's actually being studied and why it matters to you. He covers the surprising cognitive benefits of coffee and tea, the overlooked link between autoimmune disease and cancer risk, n...

Mike Sullivan is back. The CEO of the Loomis Agency and longtime friend of Dr. Lewerenz returns for a conversation that gets real fast. Between motocross memories and Supercross weekend in Detroit, the two open up about near-death experiences, second chances, and what it actually takes to stay alive long enough to appreciate life. Dr. Lewerenz also breaks down a genetic cholesterol marker most doc...

This week on The Deep Six, Dr. James Lewerenz is back with another Ask Me Anything episode, tackling the questions hitting his inbox on hormones, cancer, microplastics, and dementia. He breaks down why hormone replacement therapy is foundational to brain volume, bone density, and muscle mass, and why fear of it often does more harm than good. He makes a bold case that the future of beating cancer...

On this episode of The Deep Six Podcast, Dr. James Lewerenz sits down with Sifu Patrick Donahue to explore how discipline, consistency, and purpose shape both physical and mental health. Drawing from decades of martial arts training and teaching, Patrick explains why real confidence is built through daily effort, emotional regulation, and keeping promises to yourself. The conversation connects mar...

This week on The Deep Six Podcast, Dr. James Lewerenz answers some of the most common and misunderstood health questions in this Ask Me Anything episode. He breaks down why recurrent herpes outbreaks signal immune stress, how sleep, training load, diet, and arginine balance influence viral flares, and what long-term inflammation may mean for brain health. Dr. Lewerenz also addresses cytomegaloviru...

This week on The Deep Six, Dr. James Lewerenz sits down with Chef Nishan Andonian of Entice Catering LLC to explore the powerful connection between food, flavor, and long-term health. Chef Nishan shares how scratch cooking, fresh herbs, and thoughtful techniques can transform clean eating into something sustainable and deeply satisfying. Together, they discuss gut health, gluten sensitivity, prote...

On this episode of The Deep Six, Dr. James Lewerenz sits down with Nik Hughes, drummer for the rock band Bush, to explore the physical, mental, and emotional demands of life on tour. Nik shares how drumming at a high level requires intentional training, long warmups, hydration, and recovery, especially as he ages and manages past injuries. The conversation connects performance with longevity, high...

In this AMA episode of The Deep Six Podcast, Dr. James Lewerenz answers listener questions that span daily habits, emerging diagnostics, and long-term brain and heart health. He walks through his personal non-negotiables, including gratitude, movement, heat and cold exposure, and intentional community, explaining how small daily practices shape physiology over time. Dr. Lewerenz also highlights ne...

On this episode of The Deep Six Podcast, Dr. James Lewerenz sits down with Dr. Samantha Buchanan, DACM, owner of Pointe Acupuncture & Integrative Medicine, to explore how Chinese medicine and Western functional medicine can work together in modern longevity care. Dr. Buchanan shares how a serious running injury led her from a pre-med path into acupuncture, herbs, and integrative practice, alon...

On this episode of The Deep Six, Dr. James Lewerenz sits down with Cathy Eason, MS, BCHN, FNTP, Chief Science Officer at Berkeley Life, to unpack why nitric oxide is so central to vascular health, aging, and daily performance. Cathy explains how nitric oxide works in the body, why levels decline with age, and why endothelial health must be a lifelong priority, not just a concern after symptoms sho...

On this episode of The Deep Six Podcast, Dr. James Lewerenz welcomes emergency medicine physician Dr. Roya Caloia for a powerful conversation about the realities of life in the ER. Dr. Caloia shares how her journey shifted from public health and OB-GYN aspirations to discovering her passion for emergency medicine, where every day offers an opportunity to impact lives during their most critical mom...

Dr. Lewerenz is back with his second AMA, answering listener questions that speak to common challenges many of us face. He explains why aging and autoimmunity can lead to frequent falls and fractures and offers ways to build stronger bones, protect balance, and stay active at any age. He also shares practical strategies for better sleep, including magnesium, melatonin, grounding sheets, peptides,...

On this episode of The Deep Six Podcast, Dr. James Lewerenz welcomes world-renowned neurosurgeon Dr. Daniel Fahim for an in-depth discussion on spine health, chronic pain, and the latest surgical advances. Dr. Fahim, recognized among the nation’s top neurosurgeons, shares his journey from early fascination with the brain to performing over 700 surgeries a year. He explains how minimally invasive s...

Dr. James Lewerenz hosts his first Q&A, tackling listener questions with clear, science-based answers. From probiotics and hormone balance to EMF safety, immune support, and emerging therapies, he explains how targeted actions can create lasting health improvements. He highlights the foundational role of gut health, why probiotics belong in most supplement plans, and how daily habits influence...

Dr. James Lewerenz welcomes Bionicc Body Screening’s Ryan Ringold to share the personal story behind their full-body MRI screening mission, inspired by his father’s late-stage cancer diagnosis. They explore how early detection through imaging can uncover life-threatening conditions like cancer, aneurysms, and liver disease before symptoms ever appear. You’ll learn what full-body MRI can and cannot...

Dr. Lewerenz welcomes James LaValle for a deep dive into recovery, wearables, and metabolic health. They discuss the importance of balancing training with recovery by focusing on sleep, nutrition, and breathing techniques. James shares how to use fitness trackers without becoming overly fixated on the numbers. They cover GLP-1 medications for weight loss and the need to preserve lean muscle throug...

On this episode of "The Deep Six," Dr. Lewerenz sits down with Dr. Jeff Haddad, founder of Rochester Advanced Dentistry and the Michigan Center for TMJ and Sleep Wellness, to explore the powerful connection between oral health and full-body wellness. They uncover how jaw misalignment and sleep apnea often go undiagnosed, leading to symptoms like migraines, vertigo, fatigue, and even increased risk...

On this episode of The Deep Six Podcast, Dr. James Lewerenz and Dr. Joel Kahn spotlight the often-overlooked importance of heart health, urging early screening as a vital step in prevention. They recommend a coronary artery calcium (CAC) score around age 45 for men and post-menopause for women, with advanced imaging like coronary CT angiograms offering even deeper insight. The conversation also ex...

This special Mother’s Day episode of The Deep Six Podcast features Dr. James Lewerenz and his mom, Betty, in a heartfelt conversation about aging with strength, gratitude, and joy. Betty shares how daily gratitude, physical activity, and lifelong learning have helped her stay vibrant and independent. Her routine includes weightlifting, swimming, and reading - habits that support both body and mind...

Dr. Lewerenz welcomes Lauren Zessin for a powerful breakdown of the top 10 causes of death—and how most are preventable. From heart disease to stroke, they unpack the risks, the science, and the real-life strategies to tip the odds in your favor. You’ll hear why cardiac calcium scores beat standard stress tests, how gut health and stress levels connect to cancer, and why balance training might sav...