Solving the Puzzle with Dr. Datis Kharrazian

This episode explores the world of the immune system's response to pathogens and chronic infections. Dr. Kharrazian discusses the intricate mechanisms pathogens use to evade the immune system, leading to chronic infections and reactivations. He speaks on the impact of immune compromise, genetic factors, and other environmental influences on the severity of infections and autoimmune diseases. He al...

In this episode, Dr. Datis Kharrazian discusses hormone disorders and their impact on puberty, perimenopause, menopause, and andropause. He discusses the onset of hormone-related issues, such as puberty and perimenopausal transition, and provides evidence-based strategies for addressing menstrual irregularities, hormone imbalances, adrenal function, and more. Dr. Kharrazian also delves into the ef...

In this episode, Dr. Kharrazian provides insights on growth hormone deficiency, testosterone replacement therapy, strategies for PCOS and infertility, and much more. From discussing the use of growth hormone stimulating peptides to addressing heavy menstrual bleeding and gallbladder issues, this episode offers evidence-based approaches to optimizing endocrine function. Learn more at drknews.com Fo...

In this episode we dive into the intricate web of hormone imbalances, menstrual disorders, and andropause. We explore the impact of estrogen and progesterone imbalances on the menstrual cycle, as well as the role of prostaglandin imbalances in conditions like dysmenorrhea and PMS. We also uncover the complexities of andropause in males and address the various symptoms and treatment options availab...

In this episode, Dr. Kharrazian delves into the world of hormone imbalances, microbiome diversity, and the impact of polyphenols and phytoestrogens. He discusses evidence-based strategies for autoimmune disease, brain health issues, and chronic health conditions, and sheds light on the pivotal role of gut health in estrogen metabolism. He also addresses nutraceutical support for insulin resistance...

In this episode, Dr. Kharrazian provides insight into the impact of obesity on male and female hormone imbalances, infertility, and the body's endocrine system. From the role of adipose tissue to the effects of hormone replacement therapy, this episode explores the complexities of hormone balance and offers evidence-based strategies for managing these crucial aspects of health. Dr. Kharrazian disc...

In today's episode, we dive into the impact of hormone imbalance on overall health. From the critical role of adequate sleep in hormone regulation to the potential effects of environmental chemicals on endocrine function, Dr. Kharrazian shares valuable insights and evidence-based strategies for managing hormone imbalances. For patient-oriented courses, visit https://drknews.com/online-courses/ For...

In this episode, we take a deep dive into the intricate world of hormone imbalances and hormone replacement therapy. Dr. Kharrazian discusses the latest research findings, revealing a clear linear dose-response relationship between oral contraceptive use and the risk of hypertension, as well as the links between hormone replacement therapy and various health concerns. We explore the complexities o...

In this talk, Dr. Kharrazian reviews the many pathways through which inflammation impacts the body. In a nutshell, inflammation is like throwing fuel onto the fire. Wherever you already have issues with pain or inflammation, an inflammatory diet and other triggers will simply worsen those conditions. Aging is another consideration — as we age we naturally become more prone to inflammation due...

The concept of small intestinal bacterial overgrowth is one that is becoming very popular but also widely misunderstood and confusing. Compared to the large intestine, there are very few bacterial species in the small intestine. When SIBO happens, the bacteria in the large intestine translocate to the small intestine causing fermentation, bloating, and excessive distension. Foods that commonly tri...

Chronic gut health problems some people face can stem from brain-related dysfunction. Key groups of brain-related problems can cause gut problems: neurodegeneration, traumatic brain injury, neurological autoimmunity, and neurodevelopment disorders. In this episode, I discuss these key categories of brain-related problems and how they affect the gut through the vagus nerve as one of its functions i...

Glutathione is the body’s master antioxidant, meaning it helps protect your cells from pathogens such as viruses. It also lowers the risk of developing food and chemical sensitivities, and is a powerful ally in managing autoimmunity and preventing tissue destruction. Unfortunately, environmental toxins, chronic stress, unhealthy diets, inflammation, medications, alcohol, aging, and many other...

A complete thyroid panel can tell you about thyroid function, feedback loops, and how thyroid hormones are converting. The main thyroid markers are TSH, the pituitary hormone-stimulating gland, and T4 and T3, which are produced by the thyroid gland. Thyroid hormones are bound to proteins called thyroid hormone-binding globulins. Those are total T4 and total T3. T4 is converted to T3, which al...

If you have hypothyroidism, the first question you have to ask yourself is how long did it take to finally get diagnosed? Most people do not receive a diagnosis immediately after symptoms appear. What happens to most people instead is they struggle with symptoms for months or years: Hair loss, constipation, cold hands and feet, fatigue – symptoms get worse and worse and they keep developing new on...

If you have hypothyroidism, there is a greater than 90% chance that Hashimoto's, an autoimmune disease, is the cause of your hypothyroidism. If you have one autoimmune disease, then you probably have other autoimmune diseases. Researchers once believed that autoimmunity was an isolated dysfunction of the gland from an autoimmune response that had no other systemic effects. Current research shows a...

The two main antibodies to screen for Hashimoto’s are thyroid peroxidase (TPO) antibodies and thyroglobulin (Tg) antibodies. It’s important to check both because either one can be elevated, although TPO is more commonly elevated. An important thing to understand about thyroid antibodies, which are used to screen for autoimmune Hashimoto’s hypothyroidism, is that the antibody itself isn't directly...

Why is it so difficult to get diagnosed with hypothyroidism and Hashimoto's in the current healthcare system? As a healthcare practitioner, it's pretty rare when a patient says, "Yeah, I had symptoms and right away they diagnosed me with hypothyroidism.” Several reasons go into why it’s hard to get a hypothyroidism diagnosis: • The disease comes on slowly so it can go misdiagnosed for years. • Doc...

In this episode Dr. Kharrazian discusses the commonly asked question, which thyroid hormone replacement works best? The important thing to understand is there is not one optimal thyroid replacement. Issues exist with all types of replacement depending on the person and their unique situation and needs. Each person must figure out what their challenges and needs are and which thyroid hormone is mos...

Do you feel sleepy after you eat? Or do you feel energized after eating? Both responses indicate blood sugar instability. Chronically high blood sugar, low blood sugar, or swings between the two cause Hashimoto's flare ups and make the condition difficult to manage. At the same time, if you're in a low thyroid state from undiagnosed or poorly managed Hashimoto's, you're also susceptible to poor bl...

Today’s world is very toxic, and we all carry toxic chemicals and heavy metals in our bodies. Chelation is a popular therapy to lower heavy metal levels, however it’s important to be aware of the risks—chelation can significantly worsen health in vulnerable people. Factors to consider include your antioxidant status, blood-brain barrier permeability, immune tolerance, gut health, autoimmune status...

Endotoxemia happens when toxic byproducts from harmful gut bacteria escape through a leaky gut wall into the bloodstream. Here, they trigger significant inflammation throughout the body. Endotoxemia is linked with major depressive disorder, autoimmunity, joint disease, skin problems, poor immune resilience, difficulty recovering, aging poorly, and more. In fact, one thing people who live to 100 ha...

Contrary to popular belief, gluten intolerance is not a fad. Rates of gluten intolerance have risen dramatically due to many factors of industrialization. Unsurprisingly, significant links exist between gluten and autoimmunity, particularly Hashimoto's hypothyroidism. People with Hashimoto's low thyroid are more genetically prone to gluten sensitivity and celiac disease. Standard gluten sensitivit...

In this video, Dr. Kharrazian answers questions from members of the course Hashimoto's: Solving the Puzzle (drknews.com). Topics include: The role of thyroid binding globulin and the potential effect of birth control pills and hormone replacement. Stubbornly high TPO antibodies. The role of low dose naltrexone (LDN). What does it mean when TSH is low? What causes the swings between hyperthyroid&nb...

In this video, Dr. Kharrazian answers questions from members of the course Hashimoto's: Solving the Puzzle (drknews.com). Topics covered include: The optimal TSH level, food sensitivities and Hashimoto's, low thyroid symptoms but no diagnosis, testing total immuoglobulins before Cyrex testing, antibody testing when on immunosuppressants, CIRS and the Shoemaker protocols, why TPO antibodies are hig...

In this video, Dr. Kharrazian answers questions from members of the course Hashimoto's: Solving the Puzzle (drknews.com). Topics covered include what your thyroid antibodies mean for your Hashimoto's symptoms, how to know if a particular lab is reliable, coffee enemas, the impact of adrenal exhaustion on Hashimoto's, when to take your thyroid meds before lab testing, thyroid--brain concerns, why y...