Sigma Nutrition Radio

Links: Go to episode page (with episode resources) Subscribe to Premium Receive the Sigma Nutrition newsletter About This Episode: Numerous nutrition studies present findings of "no effect," but interpreting such results requires caution. A null finding, indicating an absence of impact from a nutrient or exposure, may not necessarily suggest a lack of effect overall. Instead, it could stem from is...

Links: Go to episode page (with supporting links/resources) Subscribe to PREMIUM Learn more about Sigma Nutrition Crushing Comparisons course About This Episode: Social comparison theory, developed by psychologist Leon Festinger in the 1950s, posits that individuals determine their own social and personal worth based on how they stack up against others. This theory suggests that people engage in s...

Questions Answered in This Epsiode: [02:16]  How would you implement a calorie surplus for "bulking" in healthy trainees without compromising their health markers? [15:25]  If you were to advise someone with a heavy workload and busy schedule on how to establish the 80/20 of a healthy lifestyle, what would you tell them? [24:36]  Is coconut oil good or bad? What about claims that it cures cancer,...

Links: Go to episode page Subscribe to Premium Sigma's recommended resources Bite Me Nutrition – Australia Instagram: @jonosteedman @dannylennon_sigma About This Episode: There is no shortage of misleading, confusing and even dangerous nutrition information on the internet. And, unfortunately, much of it can sound very convincing and appealing to people who wish to improve their health. The result...

Links: Go to episode page (with study links) Subscribe to Premium Sigma's recommended resources Get our weekly email newsletter About This Episode: Insufficient energy availability can significantly disrupt normal hormonal, metabolic, and physiological processes, prompting the body to initiate a coordinated response aimed at conserving energy. While commonly viewed as beneficial for weight loss an...

Links:  Episode page (with study links) Subscribe to Premium Join Sigma email newsletter About This Episode: The Portfolio diet is a nutritional approach that has garnered attention for its ability to reduce blood lipids and thus improve cardiovascular health. While past intervention trials have demonstrated significant reductions in blood lipids, a critical aspect often overlooked is the long-ter...

This episode is one of our  Premium-exclusive  AMA (ask me anything) episodes, where we answer questions submitted by Premium subscribers. To listen to the full 90 minute episode, you'll need to be a  Premium subscriber  and access the episode on the private Premium feed. Otherwise, you can hear a preview of the episode here. Full List of Questions: [01:50]  How should one interpret the systematic...

Links: Go to episode page (with links to studies) Subscribe to PREMIUM Join Sigma's email newsletter Sigma's Recommended Resources About This Episode: Navigating the intricate landscape of sports nutrition is one that constantly evolves and challenges our understanding of optimal athletic performance. The delicate balance between advancing research and ensuring practical applicability in the high-...

Links: Go to episode page (with study links) Subscribe to PREMIUM Receive our email newsletter About This Episode: The Oslo Diet-Heart Study was one of the earliest randomized controlled trials to explore the relationship between diet and heart disease. It aimed to investigate the impact of dietary interventions, specifically the reduction of saturated fat intake and an increase in polyunsaturated...

Links: Go to episode page (with study links) Receive Sigma's email newsletter Subscribe to PREMIUM - get study notes to this episode About This Episode: In 1959 a landmark clinical trial, often referred to as the LA Veterans Study, began with the aim to investigate the effects of replacing dietary saturated fats with polyunsaturated fats, on the progression of atherosclerosis and cardiovascular ou...

Links: Go to episode page (with resources) Subscribe to Premium Learn more about Sigma Nutrition About This Episode: The Lyon Diet Heart Study (LDHS) is often cited as one of the pivotal studies that helped establish the Mediterranean diet as a recognized and recommended dietary pattern for cardiovascular health. A clinical trial conducted in Lyon, France, the LDHS showed significant reduction in...

Links: Go to episode page (with study links) Subscribe to Premium Past episodes referenced: Episodes 493, 481 & 317 Further reading: How Diet Influences Heart Disease Risk About This Episode: The Sydney Diet-Heart Study was a clinical trial conducted in the 1960s and 1970s that aimed to examine the hypothesis that reducing saturated fat intake in the diet would lead to a reduced risk of heart dise...

Note: This is a Premium-exclusive episode, so in order to listen to the full episode you'll need to subscribe to  Sigma Nutrition Premium .  About This Episode Nutritional epidemiology has faced strong criticism over time. While some of the methodological limitations are fair, often there are criticisms that are misguided and inaccurate. In this episode, Danny touches on a few examples of the misu...

Links: Go to episode page (with study links) Subscribe to PREMIUM Receive emails from Sigma Nutrition Sigma's Recommended Resources About This Episode: The field of research exploring sex differences in exercise response has yielded intriguing findings, shedding light on the complex interplay between biology, physiology, and training adaptations. One of the fundamental areas of investigation perta...

Links: Subscribe to PREMIUM to get study notes to this episode Go to episode page to see background detail & links See our recommended resources for further learning Previous episodes referenced: SNP17: Is Personalized Nutrition Superior to General Nutrition Advice? 414: Will Machine Learning Overtake Traditional Nutrition Research Methods? 469: Chrononutrition – New Findings & Updated Views About...

Links: Subscribe to PREMIUM Go to episode page (with further reading links) Receive our weekly emails About This Episode: Sensory cues, comprising taste, smell, texture, and appearance, serve as the initial drivers that influence our food preferences and liking for particular items. These sensory cues can be both inherent, such as the natural sweetness of fruit, and learned, as in the association...

Links: Subscribe to PREMIUM Go to episode page Learn more about the podcast Sigma's recommended resources About This Episode: PREDIMED (Prevención con Dieta Mediterránea) is a landmark clinical trial conducted in Spain. The study made a huge splash due to the rarity in nutrition of having large RCTs with hard endpoints. In addition, it had results of a large magnitude; showing a 30% reduction in c...

Links: Subscribe to PREMIUM Go to episode page (with linked studies) Receive the weekly Sigma email newsletter Recommended resources About this Episode: The PROPEL (Promoting Successful Weight Loss in Primary Care in Louisiana) trial was a cluster-randomized weight loss trial, specifically tailored to address the pressing health concerns of an underserved population in Louisiana, where obesity rat...

Links: Go to episode page Subscribe to PREMIUM Recommended resources Receive Sigma's free email newsletter Learn more about the podcast About This Episode: Food frequency questionnaires (FFQs) have been widely employed in nutrition research to assess dietary intake patterns among study participants. However, debates surrounding the reliability of FFQs have persisted both inside and outside the aca...

Links: Subscribe to Premium Sigma recommended resources Learn more about the podcast About this episode: In 1985 a paper titled  "Sick Individuals and Sick Populations"  was published in the International Journal of Epidemiology. The paper, authored by eminent epidemiologist Geoffrey Rose, can be considered as seminal and important because it brilliantly raised the concept of the "prevention parad...

Links: Go to episode page Subscribe to PREMIUM Get our free weekly emails Learn more about Sigma Nutrition Radio About This Episode: The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (ATBC) stands as a seminal and pioneering research endeavor within the domain of epidemiology and cancer prevention. Conducted in Finland, the study aimed to examine the potential protective effects of alpha...

Links:  Episode page with extra resources Subscribe to PREMIUM Receive our free weekly emails Learn more about Sigma Nutrition Radio About this Episode: The field of circadian biology has long been associated with regulating diurnal physiological processes, notably the sleep-wake cycle. However, recent advances have unveiled a broader role for circadian clocks across various tissues, including ske...

Links: Go to episode page (with study links & resources) Subscribe to PREMIUM Receive our weekly newsletter More episodes on cholesterol & heart disease About This Episode: The Multiple Risk Factor Intervention Trial (MRFIT) was a groundbreaking clinical trial conducted in the 1970s and 1980s. Its main objective was to investigate the relationship between various risk factors and the incidence of...

Links: Go to episode page (with resources for this episode) Subscribe to PREMIUM Join the Sigma email newsletter Learn more about Sigma Nutrition Radio About this Episode: One of the most important and influential papers in nutrition science is one by Ancel Keys and his colleagues that was published in The Lancet in 1957. This seminal paper examined the relationship between dietary fat intake and...

This is a Premium-exclusive episode, so here you'll only hear a preview. In order to listen to the full episode you'll need to subscribe to  Sigma Nutrition Premium . About This Episode: It has been clearly demonstrated that elevated LDL-cholesterol (LDL-C), or perhaps more specifically pro-atherogenic lipoproteins, is causal in atherosclerosis development in humans. One crucial concept within thi...