Sean Hashmi, MD

Coffee is one of the healthiest beverages on the planet. But what you add to it can quietly undo every benefit. In this episode, Dr. Sean Hashmi breaks down the real science behind decaf safety, explains why popular creamers contain hidden phosphate additives that accelerate kidney damage, and separates long-standing coffee myths from medical facts. You'll learn which additives to watch for on...

The old CKD playbook -- bland diet, blood pressure pill, hope for the best -- is dead. In this live AMA, Dr. Sean Hashmi breaks down three major shifts happening right now in kidney and metabolic medicine heading into 2026. The Kidney Shift: The FDA just approved Ozempic for kidney protection in type 2 diabetes (the FLOW trial), plus new precision immunotherapy for IgA nephropathy and early data o...

Is your nightly melatonin safe? A groundbreaking study of 130,000 people presented at the 2025 American Heart Association Scientific Sessions found that long-term melatonin use was associated with nearly double the risk of heart failure. But before you panic, there's critical context you need to understand. In this episode, Dr. Sean Hashmi breaks down what this study actually found, provides a...

Coffee doesn't just wake you up. It literally changes how your brain works. In this episode, I break down the latest research on coffee and brain health. A meta-analysis of observational studies found that people who drank 2-4 cups of coffee daily had about a 20-25% lower risk of depression. And the data on Parkinson's disease is even stronger -- regular coffee drinkers showed 25-30% lower...

Stubborn belly fat won't budge despite diet and exercise? Your kidneys may be the hidden culprit. Your kidneys clear over 50% of circulating insulin. When visceral fat compresses them, insulin stays elevated and your body gets locked in fat storage mode. This episode breaks down the kidney-belly fat connection most doctors miss — and exactly how to break the cycle. In this episode: The role of...

Nearly 600 million people worldwide have diabetes. Could your morning coffee actually help protect you? In this episode, I break down what decades of research reveal about coffee and metabolic health. A meta-analysis of over 1 million people found that each daily cup of coffee was linked to about 6% lower risk of developing type 2 diabetes. People drinking 2-4 cups per day showed 20-30% lower risk...

SPOTIFY TITLE Coffee and Kidney Disease: What 2025 Research Actually Shows (Same core keyword focus works for podcast search) What if everything you thought about coffee and kidney health was wrong? Four years ago, I covered this topic in a video that hit over 2 million views. Since then, several major studies have emerged — bigger data sets, genetic insights, even research on the timing of consum...

In 2025, we crossed a historic threshold. Multiple humans survived more than six months with gene-edited pig kidneys functioning inside them, in both the United States and China. For the 100,000 Americans waiting for a kidney right now, this matters. In this episode, I break down: What actually happened with the Massachusetts General Hospital patient who lived 271 days with a pig kidney Why is six...

Every IgA Nephropathy patient asks the same question: What do I do right now to stop my kidneys from failing? In this episode, I break down the exact 5-step action plan I give every patient in my clinical practice — based on the latest KDIGO guidelines and clinical trials like DAPA-CKD, NefIgArd, and PROTECT. You'll learn: - The 3 numbers you must track and the targets to hit - Why most IgA Ne...

The right diet can cut proteinuria by 30%—without any medication changes. Most IgA nephropathy patients don't know what to eat. In this episode, I share the exact eating plan I give every patient in my practice. Simple, sustainable, and kidney-friendly. This isn't a restrictive diet where you starve—it's a sustainable approach based on the latest kidney nutrition research. ━━━━━━━━━━━━...

IgA nephropathy treatment has changed dramatically since 2021—steroids are no longer your only option. In this episode, I break down the complete treatment roadmap based on the 2021 KDIGO guidelines and the latest clinical trials. This is the same tiered approach I use with my IgA nephropathy patients every day. ━━━━━━━━━━━━━━━━━━━━ WE DISCUSS: - Tier 1 foundation therapy: RAS inhibitors, SGLT2 in...

3 lab numbers can predict if you'll need dialysis in 10 years—and most IgA Nephropathy patients aren't tracking them correctly. In this episode, I break down the exact labs my IgAN patients monitor to prevent kidney failure. I'll show you how to read your lab report, explain the MEST-C biopsy score, and walk you through a free prediction tool that calculates your personal 5-year risk....

Blood in the urine after a cold could be the first sign of IgA nephropathy—the most common kidney disease you've never heard of. This is Episode 1 of a comprehensive series where I break down everything you need to know about diagnosis, treatment, and prognosis. In this episode, I explain what IgA nephropathy is (an immune system miscommunication that causes kidney damage), who gets it, why ge...

Strict ketogenic diets keep you thin—but what's happening inside your liver, pancreas, and kidneys? A groundbreaking 2025 study in Science Advances followed mice on strict ketogenic diets for nearly a year and revealed a disturbing metabolic paradox: while preventing weight gain, long-term keto triggered severe hyperlipidemia, fatty liver disease, and pancreatic insulin dysfunction. In this ep...

Spotify Description for Kidney Health AMA 2025 Your kidney test might be lying. A landmark 2025 JAMA study of 860,000 patients reveals when standard creatinine tests fail to detect early kidney disease—and what nephrologists now use instead. Plus: scientists discover "emergency cells" that could stop kidney scarring, breakthrough drugs protecting multiple organs simultaneously, and the t...

1 in 4 people on Ozempic lose almost NO weight—discover why GLP-1 medications fail for 25% of patients and what to do about it. If you're taking Ozempic, Wegovy, Mounjaro, or Zepbound and seeing minimal weight loss, this episode reveals exactly why—and how to fix it. One in four patients are classified as non-responders, losing less than 5% body weight even after months of treatment. As a boar...

PKD affects 1 in 500 people—here's what you need to know to protect your kidneys. Polycystic Kidney Disease is the most common inherited cause of kidney failure, but 90% of people don't discover they have it until kidneys are already damaged. In this episode, board-certified Nephrologist Dr. Sean Hashmi reveals the early warning signs and what you can do to protect your kidney function sta...

4 medications that stop diabetic kidney failure—yet most doctors aren't prescribing them. Here's why you might be getting 1990s care in 2025. In Part 4, I reveal a 49-year-old diabetic patient with kidney function of 24 and massive protein spillage—prepared for dialysis—but only on outdated 1990s medications. No SGLT2 inhibitor. No GLP-1 agonist. No finerenone. Today I'll show you the...

Can diabetic kidney damage actually be reversed? This shocking case proves it's possible. In Part 3 of our diabetic kidney disease series, I reveal a real patient case that challenges everything you've been told about "irreversible" kidney damage. A 43-year-old woman with stage 3A diabetic kidney disease—kidney function of 58, severe protein spillage at 180 mg/g—was told by her p...

Dr. Sean Hashmi, board-certified nephrologist and obesity medicine specialist, witnessed something at his kids' wrestling tournament that made him want to run over and intervene—coaches handing out energy drinks to 12-year-olds like water bottles. In this essential episode for wrestling parents, Dr. Hashmi reveals three critical hydration mistakes happening at youth tournaments that can trigge...

Three weeks ago, a 52-year-old patient discovered his kidneys were at 40% function—despite feeling completely fine. His story reveals the silent catastrophe affecting 38 million Americans with diabetes right now. In this episode, board-certified nephrologist Dr. Sean Hashmi breaks down exactly how diabetes destroys your kidneys through 5 devastating phases, often without any symptoms until it's al...

➤ Follow this podcast for more evidence-based health insights: https://open.spotify.com/show/6HX1nq6RFoqcwzwh4L9cIM ➤ Join 5,000+ getting my free newsletter: https://www.selfprinciple.org/newsletter In this episode: • Dr. Sean Hashmi, MD, MS, FASN—board-certified Nephrologist and Obesity Medicine Specialist—reveals the pre-match nutrition mistake sabotaging 90% of youth wrestlers and Brazilian jiu...

Part 1: Stop Following Kidney Diets - Here's What Actually Works (Evidence-Based) ➤ Follow this podcast for more evidence-based health insights: https://open.spotify.com/show/6HX1nq6RFoqcwzwh4L9cIM ➤ Join 5,000+ getting my free newsletter: https://www.selfprinciple.org/newsletter In this episode: • Dr. Sean Hashmi, MD, MS, FASN—board-certified Nephrologist and Obesity Medicine Specialist—revea...

➤ Follow this podcast for more evidence-based health insights: https://open.spotify.com/show/6HX1nq6RFoqcwzwh4L9cIM ➤ Join 5,000+ getting my free newsletter: https://www.selfprinciple.org/newsletter In this episode: • Dr. Sean Hashmi, MD, MS, FASN—board-certified Nephrologist and Obesity Medicine Specialist—reveals how popular wellness habits are secretly damaging your kidneys. • You'll discov...

➤ Follow this podcast for more evidence-based health insights: https://open.spotify.com/show/6HX1nq6RFoqcwzwh4L9cIM ➤ Join 5,000+ getting my free newsletter: https://www.selfprinciple.org/newsletter In this episode: • Dr. Sean Hashmi, MD, MS, FASN—board-certified Nephrologist and Obesity Medicine Specialist—reveals the shocking truth about heavy metals hiding in everyday foods. • You'll discov...