Rational Optimization /w Elias Schlie

This month, I built AI agents, I moved, I fasted, and I hiked. In this podcast, I share the stories that I experienced and the insights I found. YouTube version My website: eliasschlie.com Quick Stats 📊⏱️ Total focused work: 288 hours and 46 minutes🗓️ That’s an average of 9 hours and 57 minutes every single day — weekends included! 💾 Full breakdown publicly available here: eliasschlie.com What I...

**June 2025: The Month I Started Building** Quick Stats 📊 ⏱️ Total focused work: \~300 hours 🗓️ That’s 9 hours and 49 minutes every day (including weekends) 💾 Full work log published at [https://github.com/EliasSchlie/Working\_Hours](https://github.com/EliasSchlie/Working_Hours) What I spent my time on ⚡ * Finished exams for 9 university courses in Cognitive Science & AI (across three diffe...

eliasschlie.com

eliasschlie.com

My website 🐭 FDA Plans to Replace Animal Testing — A Roadmap to Reducing Animal Testing in Preclinical Safety Studies 🤖 Why Didn't AI Discover a Bunch of Drugs Yet? — Progress, Pitfalls, and Impact of AI-driven Clinical Trials (Wilczok & Zhavoronkov, 2025) ⏰ LinAge2 – Aging Clock Update — Providing actionable insights and benchmarking with epigenetic clocks (Fong et al., 2025) 🚀 Fronti...

My website

1) 🐁 The Rodent Aging Interventions Database (RAID) 2) 🧫 High-Throughput Yeast Aging Study 3) 🤖 Metabolic Digital Twins 4) 🏙️ How Cities Can Be Used to Learn About Aging and Exposome Influences 5) 🐷 First-ever pig-human liver transplant

⁠⁠My Website

⁠My Website

My Website

My website

In this podcast, I share my experience from being in the core organizing team of Zelar. City, a Longevity Pop-up city Links: - ⁠Zelar. City 00:00 - Intro 00:55 - What is a Pop-up city? 04:06 - What makes Zelar. City special? 05:49 - How I came to work at Zelar 10:12 - Month leading up to Zelar 10:47 - At Zelar.city 12:41 - Daily experience at Zelar.city (Longevity pop-up City) 16:18 - Zelar. City...

Zelar. City is a Longevity pop-up city. In this episode, the team comes together, discusses longevity, it's bottlenecks and reflects on their experience in Berlin. Links: - Learn about Longevity - Sophia DAO - Zelar. City - Anatoly's blog

Links: - ⁠Learn about Longevity⁠ - ⁠Sophia DAO⁠ - ⁠Zelar. City⁠ - ⁠Anatoly's blog

Watch on YouTube Vipassana website

Summary In this conversation, Alan Graves, CEO of DoNotAge.org, discusses the current state of the longevity supplement industry, emphasizing the importance of research and transparency. He highlights the need for consumers to be informed about the quality of supplements and the potential for aging to be reversible. Alan shares insights from his experiences in the industry, including his participa...

Summary In this conversation, Professor Hans Meij discusses the importance of focusing on health span rather than just longevity. He emphasizes the need for early interventions in healthcare, the challenges posed by smoking, and the role of innovative initiatives like pop-up cities in advancing longevity research. He also highlights the significance of building networks among professionals in the...

Charles Mattocks Links - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Zelar City Website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠What is Zelar City?⁠⁠⁠⁠⁠ - ⁠⁠Reversed Longevity Trailer⁠⁠ - As soon as it's out, you will be able to find "Reversed Longevity" on Amazon Prime, Tubi, or Glue TV Chapters 00:00 Introduction to Rafid Fadul and Longevity 00:41 Introduction to Rafid and His Journey 03:33 What is Cenegenics? 05:07 What is Zivian health? 07:20 H...

Summary In this conversation, Charles discusses his latest documentary 'Reverse Longevity', exploring the concept of longevity and health interventions. He emphasizes the importance of making health information accessible to the general public and shares insights on the production process of health documentaries. Charles also reflects on the personal impact of longevity research on his life and th...

Summary In this conversation, Andrea Maier, a prominent longevity advocate, discusses her work in the field of aging and health optimization. She emphasizes the importance of understanding organ-specific aging clocks, the need for evidence-based practices, and the significance of healthspan over lifespan. Andrea also highlights the challenges in longevity research, the role of pop-up cities in fos...

Kennedy Schaal is the CEO of Rejuve.bio, a biotech company with the goal of solving aging by building AGI for drug discovery. Summary In this episode, Kennedy Schaal introduces her company Rejuve.bio which comes out of the SingularityNet. Kennedy Schaal and I discuss the intersection of data, AI, and collaboration in the longevity sector. We explore the importance of community engagement, the pote...

Summary In this conversation, Jasmine Smith, CEO of Rejuve AI, discusses the decentralization of health data. She explains how their app incentivizes users with crypto tokens for contributing health data, the importance of personalized health insights, and the potential for longevity through scientific advancements. In the end, we get a bit personal, and you will learn about Jasmine's passion outs...

Nathan is an investor in the longevity space and the co-founder of the Longevity Biotech Fellowship and Vitalism, the longevity community. In this conversation, Nathan Cheng discusses the vision and moral imperative behind the fight against aging and death. He emphasizes the importance of community, alignment, and innovative approaches to longevity, including the establishment of longevity states...

In this episode, I sit down with Adam Gries to discuss the founding of Vitalism , a community dedicated to tackling aging through groundbreaking and innovative approaches. Together, we delve into the concept of network states and pop-up cities as revolutionary frameworks for collaboration and experimentation in the longevity space. Adam shares insights on how traditional approaches to aging are fa...

Summary In this conversation, Judith Mueller discusses her extensive experience in the field of longevity and biohacking, particularly focusing on women's health. She shares insights on the importance of community, the role of clinics in longevity, and her vision for a biohacked village for entrepreneurs. Judith emphasizes the need for standardized offerings in longevity clinics and the signif...