Mark Ebell

Primary Care Update

Health EN ↓ 210 episodes

Four healthily skeptical primary care physicians discuss the latest in primary care medicine. Join Essential Evidence Editor Mark Ebell MD, Rush University's Kate Rowland MD, MSU Professor of Medicine Gary Ferenchick MD, and POEMs co-founder Henry Barry MD, MS for this fast-paced weekly update on evidence-based primary care.

Author

Mark Ebell

Category

Health

Podcast website

podcasters.spotify.com

Latest episode

Jul 2, 2026

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Episodes

Episode 135: osteoporosis treatment, evolocumab, mifepristone for adenomyosis, and ambulatory BP 16.08.2023

This week, Kate, Gary, Mark and Henry discuss treatments for osteoporosis in post-menopausal women, the effect of adding evolocumab to a statin - a reanalysis of the FOURIER trial, using mifepristone for painful adenomyosis, and real world data comparing 24-hour ambulatory BP with clinic readings.

Primary Care Update Episode 134 02.08.2023

This week, Kate, Gary, Henry and Mark discuss some fun throwbacks to 2003, the new first line medications for treating T2DM, whether you can take a diuretic at bedtime, and how to manage perioperative antihypertensive medications. And a quiz. Get CME credit at iafp.com just for listening, go to their education Web page.

Episode 133: bilirubin in infants, rest after concussion, child abuse, and why words matter 19.07.2023

This week, join Kate, Henry, Gary and Mark as they discuss point of care bilirubin tests for neonatal jaundice, guideline for evaluating children in close contact with abused children, early return to activity after concussion, and terminology preferences by patients being treated for substance use disorder.

Episode 132: new drug for hot flushes, screening for autism, and steroids for pneumonia 03.07.2023

This week, Kate, Henry and Mark discuss a new drug therapy for vasomotor symptoms of menopause, the accuracy of the M-CHAT tool for autism, and the value of steroids for severe community-acquired pneumonia. And Henry tells a joke about hot air balloons. And the quiz.

Episode 131: non-STEMI management in frail elderly, diagnosing secondary HTN in kids, and RSV vaccine for pregnant women 21.06.2023

This week, while Gary tries to learn French in of all places France, Kate, Mark and Henry discuss management of non-STEMI in frail older adults, identifying children with secondary hypertension, and RSV vaccination in pregnant women

Episode 130: bempedoic acid, polypills and dementia, prophylaxis for STIs, and interpreting asymptomatic CAD 13.06.2023

This week Kate, Gary, Henry and Mark talk about bempedoic acid for the prevention of ASCVD, the polypill and cognitive decline in the elderly, post-exposure prophylaxis in persons at high risk of STIs, asymptomatic CAD and subsequent AMI risk. And do you know how long ankle arthroplasties last?

Episode 129: estimating mortality in acute HF, a new migraine drug, and 15 year f/u of the largest RCT of prostate CA treatment 25.05.2023

Kate, Gary and Henry discuss 3 new studies: a clinical decision support tool to assess mortality risk in patients presenting with acute heart failure, a new intranasal medication for treating acute migraine attacks, and the pros and cons of different approaches to treatment of low grade prostate cancer.

Episode 128: BP targets, treatment resistant depression, angry and disruptive patients, and putting infants to bed 10.05.2023

This week our intrepid team of primary care physicians (Kate Rowland, Henry Barry, Gary Ferenchick and Mark Ebell) discuss treatment of resistant depression in older adults, recognizing and managing angry and disruptive patients, the best way to settle a cranky infant, and the AAFP 2022 Guideline on BP targets in adults with hypertension.

Episode 127: LDL targets, genicular nerve blocks, adding cytology to HPV, and HCTZ to prevent stones 02.05.2023

This week, Henry, Kate, Gary and Mark discuss: treating to LDL target or intensity-based statin therapy for adults with CAD, genicular nerve blocks for pain relief in adults with DJD, the value of adding cytology to HPV for cervical cancer screening, and HCTZ for preventing kidney stone recurrence 

Episode 126: screening for genital herpes, semaglutide for obesity, ACG guideline on lower GI bleed, and whether invasive management is helpful for stable CAD 11.04.2023

This week, Gary, Kate, Henry and Mark discuss 2 new studies and 2 new guidelines: screening for genital herpes infections from the USPSTF, semaglutide injections in obese adolescents, ACG guidelines for acute lower GI bleeding, and invasive vs. noninvasive management of patients with stable CAD. And Henry manages to not talk about baseball!

Episode 125: reducing seizure frequency, antidepressants for pain, and periop anticoagulation 31.03.2023

Kate is at the Cubs opener today, so you'll have to settle for Mark, Gary and Henry as they discuss reducing seizures in young kids, the best antidepressants for managing pain, and new ACCP guidelines for peri-operative management of anticoagulation and antiplatelet agents.

Episode 124: etonogestrel and lactogensis, celiac guidelines, FODMAPS for IBS, and a new CV drug 20.03.2023

This week, join Kate, Henry, Gary and Mark as they discuss: immediate insertion of etonogestrel contraception and lactogenesis, ACG Guideline for managing patients with celiac disease, FODMAPS diet for irritable bowel, and a new way to lower cholesterol and reduce CV events.  

Episode 123: mindfulness, PRP for Achilles rupture, lecanab for Alzheimer's, and VTE prophylaxis post-fracture 01.03.2023

This week, Kate, Gary, Henry and Mark discuss mindfulness based stress reduction for anxiety, platelet rich plasma for Achilles tendon ruptures, lecanamab for Alzheimer’s, and VTE prevention after fracture. Is aspirin sufficient?

Episode 122: predicing dementia, incentives to quit smoking, HP eradication for dyspepsia, and comparison of diabetes meds 15.02.2023

Join Kate, Mark, Gary and Henry as they discuss whether we should (or can) use biomarkers to predict mild cognitive impairment or dementia, financial incentives to promote smoking cessation, the efficacy of HP eradication for functional dyspepsia, and results of the glycemic control arm of the GRADE Trial.

Episode 121: vitamin C for sepsis, probiotics for halitosis, and dyspepsia evaluation 01.02.2023

This week, Kate, Henry and Mark discuss vitamin C for sepsis, probiotics for treating halitosis, and new UK guidelines for evaluation of dyspepsia. Plus a quiz: how much time do we primary care docs spend every day delivering preventive services?

Episode 120: sleepy time for kids, crenezumab for Alzheimers, prognosis after TKA, and intermittent fasting 18.01.2023

Join us this week as Kate, Henry, Gary and Mark discuss: nonpharmacologic sleep interventions in children, crenezumab for treating patients with early Alzheimers, prognosis after knee replacement, and time restricted eating (“intermittent fasting”) for weight loss. Henry and Gary are oxygen deprived and recording in Big Sky, teaching a CME course. You can join all four of us on March 3 and 4 in Sc...

Episode 119: insomnia treatment, when to take HTN meds, colonoscopy effectiveness, and chlorthalidone vs HCTZ 04.01.2023

An action packed episode with some truly landmark studies to discuss. Join Kate, Henry, Gary and Mark as they discuss drug treatment of insomnia, when to take your anti-hypertensive meds, whether colonoscopy is effectiveness, and chlorthalidone vs HCTZ. 

Episode 118: hyperbilirubinemia, diabetic neuropathy, acute heart failure, and screening for CVD 10.12.2022

This week, Kate, Gary, Henry and Mark discuss a new guideline for managing jaundice in babies, treating painful diabetic peripheral neuropathy, acetazolamide for patients hospitalized with CHF, and screening for CVD in older men.

Episode 117: the plague, treatment of prediabetes, asymptomatic bacteriuria, and the value of pyuria 27.11.2022

This week, Mark, Kate, Henry and Gary discuss black Friday, black Death; long term outcomes of managing patients with impaired glucose tolerance or "pre-diabetes" (Henry hates that term); treating asymptomatic bacteriuria in nursing home residents; and the significance of microscopic pyuria in asymptomatic patients.

Episode 116: Polypills, yoga for migraine, best 2nd drug for DM, and Paxlovid for omicron 09.11.2022

Gary, Kate, Henry and Mark discuss 4 POEMs: polypills for secondary prevention of cardiovascular disease, yoga for migraines, the best 2nd drug for type 2 DM, and clinical outcomes with Paxlovid in the omicron wave.  Do check out Essential Evidence Plus if you want all of the POEMs each month and a great primary care reference.

Episode 115: bisphosphonates and mortality, COVID rebound, and 2 IBS treatments 29.10.2022

This week, join Mark, Kate, Gary and Henry as they discuss 4 studies: mortality reduction from the treatment of osteoporosis, hypnosis for patients with IBS, COVID rebound syndrome, and low FODMAP diets in patients with IBS.

Episode 114: cannabis for chronic pain, scaphoid fractures, and steroids for renal colic 12.10.2022

On this week's podcast, our intrepid trio of family physicians discusses cannabis for chronic pain, treatment of scaphoid fractures in adults, and adding dexamethasone to ketorolac for adults with renal colic.

Episode 113: POC respiratory panels, fever in adults, and CV benefits of SGLT-2's 28.09.2022

Today Kate, Gary and Henry talk about point of care respiratory panels for children, outcomes of controlling fever in adults, and SGLT2 inhibitors and heart failure. Mark is enjoying Murphy's in Cork but still managed to do the post-production.

Episode 112: buckle fractures, tirzepatide for obesity, and stroke risk with severe carotid stenosis 14.09.2022

This week, Henry, Gary and Mark discuss: managing children with torus (buckle) fractures of the distal radius, tirzepatide for treating obesity in adults without T2DM, and stroke risk in patients with asymptomatic severe carotid artery stenosis. Kate couldn't join us this week, but check out her thoughtful essay in the journal Family Medicine  

Episode 110: pharmacogenomics, functional abdominal pain in kids, vitamin D and fractures, and a T2DM guideline 03.09.2022

This episode, Henry, Kate, Mark and their colleague Gary Ferenchick from MSU discuss: pharmacogenomic-guided antidepressant therapy, non-drug interventions for children with functional abdominal pain, Vitamin D and fracture risk in the elderly, and NICE guideline for persons with T2DM.

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