Permission With Shadia Akle

Dr. Jonathan Kuo is a double board-certified anesthesiologist, interventional pain specialist, and the visionary founder of Extension Health. He is at the absolute forefront of human optimization, moving beyond traditional medicine to focus on the root causes of aging: cellular health and physiological performance. In this episode, Shadia Akle and Dr. Kuo dive into the "Future of Longevity&qu...

In this episode of Permission with Shadia Akle, we sit down with Mindvalley speaker and entrepreneur John Lee to explore the profound shift from living a "comfortable" life to one of true alignment and purpose. John shares his personal journey from a successful career in film animation to breaking a long-standing family cycle to build his own destiny. If you’ve ever felt that nothing is...

On this week's episode of Permission with Shadia Akle , we dive deep into the biological "command center" of the human body with multi-board certified physician Dr. Azza Halim. While many view aesthetics as purely surface-level, Dr. Halim reveals why she looks at your biomarkers and gut microbiome before she ever treats your skin. In this wide-ranging conversation, we explore: The Gu...

On this episode of Permission with Shadia Akle , I sit down with Mike Mutzel, the founder of High Intensity Health and one of the leading voices in metabolic science. If you feel like you’re doing everything right, eating clean and training hard, but your body still isn't meeting you halfway, this conversation is for you. Mike reveals why "pushing harder" might actually be the thing...

On this episode of Permission, Dr. Mary Pardee, a naturopathic and functional medicine doctor, reveals why years of protocols, supplements, and testing often leave patients feeling more stuck than ever before. After spending her own life struggling with unexplained gut issues, Dr. Pardee discovered that the "magic bullet" isn’t always physical. We dive deep into the science of the gut-br...

This episode features a powerful conversation with Shawn Wells, a world-renowned biochemist and the man the industry calls the "World’s Greatest Formulator." Despite his massive professional success, Shawn’s personal journey began in a very different place, struggling with morbid obesity, chronic autoimmune diseases, and deep depression that led to frequent suicidal thoughts. In this vul...

Your gut has been trying to tell you something. This is the episode where you finally listen. The bloating that started in your twenties. The exhaustion no amount of sleep touches. The anxiety that arrives before your thoughts do. The autoimmune diagnosis no one in your family has. What if none of it is random? What if it's not your hormones, your stress levels, or your imagination, and what i...

You are more microbe than human and your gut bacteria are deciding whether you heal or stay sick. Research microbiologist and gut health pioneer Kiran Krishnan breaks down the gut-brain connection, how childhood trauma lives in your microbiome, why a single course of antibiotics can wipe out 90% of your gut, and why no matter what your body has been through, repair is always possible. In this epis...

By the time you're 40, your body has already lost a significant amount of the one molecule responsible for keeping your cells alive, energized, and repairing themselves. It's called NAD. Without it, you'd die in 30 seconds. And almost no one is talking about why it disappears, or what actually works to bring it back. I sat down with Dr. Nichola Conlon — molecular biologist, longevity s...

Welcome to Permission, a space for the conversations that ask us to come home to ourselves. For Episode 2, I sat down with Dr. Vincent Pedre , gut health expert and integrative medicine physician. We talk about what the body remembers, why our symptoms are rarely random, and how emotional trauma shapes the gut in ways most doctors miss. In this conversation: The connection between heartbreak, loss...

Welcome to Permission , a space for the conversations that ask us to come home to ourselves. For the first episode, I sat down with Annalie Howling , author of Unapologetic and a trauma specialist. We talk about shame, self-abandonment, and what it actually means to come home to ourselves. In this conversation: Why shame is a liar. The difference between guilt and shame. The inner critic as the cu...

Welcome to Permission with Shadia Akle. Here's what nobody talks about in wellness: you can do everything right and still not feel right. The supplements, the protocols, the labs, the clean eating, and your body is still asking for something none of it can give. Your body isn't broken. It never was. It's been carrying what you couldn't. The job that drained you. The relationship th...