Out of the Blue: An AJRCCM Podcast

Dr. John Fleetham chats with Dr. Sonal Munsiff and Dr. Raquel Duarte about their article, " Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline ." 

Dr. John Fleetham chats with Dr. Paolo Denti, Dr. Elisa Ignatius, Dr. Jason Andrews, and Dr. Neil Schluger about two papers and an editorial published in AJRCCM discussing the use of isoniazid in treating patients with tuberculosis.

Dr. John Fleetham chats with Dr. Hedner and Dr. Schmickl about their articles “ A Randomized Controlled Trial Exploring Safety and Tolerability of Sulthiame in Sleep Apnea " and  “ Drug Therapy for Obstructive Sleep Apnea: Are We There Yet? ” 

Dr. Mohleen Kang chats with Dr. Margaret Salisbury and Dr. Anna Podolanczuk about their articles, " Progressive Early Interstitial Lung Abnormalities in Persons at Risk for Familial Pulmonary Fibrosis: A Prospective Cohort Study " and " Big Things Have Small Beginnings: Clinical Implications of Early Interstitial Lung Disease ." 

Dr. John Fleetham chats with Dr. Yet Kor about her article, " Assessment of Home-based Monitoring in Adults with Chronic Lung Disease: An Official American Thoracic Society Research Statement ."

Dr. John Fleetham chats with Dr. Ludovico Messineo and Dr. Simon Joosten about their articles " Hypnotics on Obstructive Sleep Apnea Severity and Endotypes: A Systematic Review and Meta-Analysis " and " The Arousal Threshold: The ‘Weakest Link’ in OSA Pathogenesis ." 

Dr. Michael Lanspa chats with Dr. Hannah Wunsch about her paper, " Evaluation of Etomidate Use and Association with Mortality Compared with Ketamine among Critically Ill Patients ."

Dr. Michael Lanspa chats with Dr. Anthony Gordon about his article, " From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU ."

Dr. John Fleetham chats with Dr. Chris Ryerson and Dr. Yet Khor about their article, " Epidemiology and Prognostic Significance of Cough in Fibrotic Interstitial Lung Disease ."

Dr. John Fleetham chats with Dr. Gozal on his article, " Senolytic-facilitated Reversal of End-Organ Dysfunction in a Murine Model of Obstructive Sleep Apnea ."

Dr. John Fleetham chats with Dr. Bijan Teja and Dr. Nicholas Bosch about their article, " Effectiveness of Fludrocortisone Plus Hydrocortisone Versus Hydrocortisone Alone in Septic Shock: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials ." 

Dr. John Fleetham chats with Dr. Barbro N Melgert and Dr. Chris Carlsten about their articles, " Inhalable Textile Microplastic Fibers Impair Airway Epithelial Differentiation " and " Inhaled Microplastics and Airway Development: Concerning Evidence from Organoid s."

Dr. Michael Lanspa chats with Dr. Michael Matthay about his article, " A New Global Definition of Acute Respiratory Distress Syndrome ."

Dr. Mohleen Kang chats with Dr. Aparna Swaminathan and Dr. Timothy Dempsey about their articles, " External Control Arms in Idiopathic Pulmonary Fibrosis Using Clinical Trial and Real-World Data Sources ” and “ The Added Power of Synthetic Control Groups: Challenging Conventional Wisdom and Trial Design in Idiopathic Pulmonary Fibrosis Research .” 

Dr. John Fleetham chats with Dr. Paula K. Schweitzer and Dr. Najib Ayas about their articles, " The Combination of Aroxybutynin and Atomoxetine in the Treatment of Obstructive Sleep Apnea (MARIPOSA): A Randomized Controlled Trial " and " Pharmacologic Therapy for Obstructive Sleep Apnea: Are We Seeing Some Light at the End of the Tunnel? "

Dr. John Fleetham chats with Dr. Surya Bhatt about his article, “ FEV1/FVC Severity Stages for Chronic Obstructive Pulmonary Disease .”

Dr Michael Lanspa chats with Dr. Imeen van der Wal and Dr. Chloe Grim on their article, " Conservative versus Liberal Oxygenation Targets in Intensive Care Unit Patients (ICONIC): A Randomized Clinical Trial ." 

Dr. John Fleetham chats with Dr. Raphael Heinzer about his article, " Pulse Wave Amplitude Drops Index: A Biomarker of Cardiovascular Risk in Obstructive Sleep Apnea ."

Dr. Michael Lanspa chats with Dr. Kevin Seitz and Dr. Matthew Churpek about their article, " Individualized Treatment Effects of Bougie vs Stylet for Tracheal Intubation in Critical Illness ."

Dr. John Fleetham chats with Dr. Molly Franke and Dr. James Brust about their articles, " Effectiveness of Bedaquiline Use Beyond Six Months in Patients with Multidrug-Resistant Tuberculosis " and “Weighting” the evidence: How much bedaquiline is enough? "

Dr. Michael Lanspa chats with Dr. Yahya Shehabi about his article, " Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III) ."

Dr. John Fleetham chats with Dr. Joseph Lewnard and Dr. Will Checkley about their articles, " Tuberculosis Diagnoses Following Wildfire Smoke Exposure in California " and " Tuberculosis, Wildfires, and Case-crossover Studies: An Epidemiological Trifecta. "

Paper discussed in today's episode: Assessing Pretomanid for Tuberculosis (APT), a Randomized Phase 2 Trial of Pretomanid-containing Regimens for Drug-sensitive TB: 12-Week Results

Papers discussed in today's episode: Cardiovascular Benefit of Continuous Positive Airway Pressure in Adults with Coronary Artery Disease and Obstructive Sleep Apnea without Excessive Sleepiness Continuous Positive Airway Pressure and Cardiovascular Risk Reduction in Patients without Excessive Sleepiness: Importance of the Pulse Rate Response

Paper discussed in today's episode: High-Flow Versus VenturiMask Oxygen Therapy to Prevent Re-Intubation in Hypoxemic Patients After Extubation: A Multicenter, Randomized Clinical Trial