Optimization Academy with Dr. Greg Jones

Neuropathy treatment often falls short—and this episode explains why nerve pain persists even when tests appear normal and medications don’t deliver real relief. In this in-depth conversation, Dr. Greg Jones sits down with Dr. Stephen Matta, a triple board-certified physician specializing in regenerative medicine, to uncover what’s often missed in the diagnosis and treatment of neuropathy. In this...

Dr. Greg Jones discusses NAD, a favorite molecule in functional medicine for its role in anti-aging. He explains how NAD contributes to DNA repair, boosts mitochondria, and provides energy, while also supporting deeper sleep. With age, energy levels naturally decline, but oral NAD supplements can help to increase NAD levels. CHAPTERS00:00 What NAD Is & Why It Matters for Longevity00:59 NAD and...

Brain Endurance Training and mental fatigue may be the missing link limiting your physical performance, and this episode reveals how your brain, not your body, could be the true bottleneck. In this high-impact conversation, Dr. Greg Jones sits down with Dr. Christopher Ring, Professor of Psychology at the University of Birmingham, to explore how cognitive load, stress, and perception of effort dir...

Dr. Greg Jones discusses the "Wolverine Stack" protocol, which utilizes specialized peptides for healing and recovery. This includes a detailed look at BPC-157 and TB-500, highlighting how these peptides for injury repair work synergistically. Learn about this advanced peptide therapy to optimize healing and recovery from various physical challenges. The information provided in this vide...

Long COVID and sports injuries are becoming impossible to ignore—and this episode explores why more athletes may be dealing with fatigue, soft tissue breakdown, and prolonged recovery after viral illness. In this powerful conversation, Dr. Greg Jones sits down with Dr. Muhammad Mansour, a naturopathic doctor and regenerative medicine specialist who treats elite athletes at the highest levels. In t...

Chronic inflammation explained—if you're dealing with fatigue, brain fog, or ongoing health issues, this episode uncovers the real root causes and how advanced lab testing can help you finally heal. In this powerful conversation, Dr. Greg Jones sits down with Dr. Clement Lee, a licensed Naturopathic Medical Doctor (NMD), to break down why so many people feel unwell despite “normal” lab results...

Hormone optimization is about more than testosterone levels. In this episode, Dr. Greg Jones sits down with Dr. Devaki Lindsey Berkson, a pioneer in functional medicine and hormone research, to explain why true longevity depends on hormone signaling, receptor sensitivity, gut health, and environmental resilience. Dr. Berkson shares why hormones function as the body’s “software,” coordinating metab...

Oxidative stress is one of the primary drivers of aging, inflammation, and chronic disease — and glutathione may be the body’s most powerful defense. In this episode, Dr. Greg Jones sits down with Dr. Nayan Patel, internationally recognized pharmacist and author of The Glutathione Revolution, to break down the science behind the body’s “master antioxidant.” As we age, glutathione production declin...

Long COVID isn’t one single diagnosis—it’s a spectrum of post-viral patterns that can affect energy, cognition, immunity, circulation, and inflammation. In this episode, Dr. Greg Jones is joined by Dr. Robin Rose, a double board-certified physician (Internal Medicine + Gastroenterology) and a leading authority on the gut–brain–immune axis, to unpack what she’s seeing clinically in patients with pe...

Healthy testosterone levels are essential for men over 40—affecting libido, muscle mass, joint health, energy, mood, and long-term longevity. In this video, Dr. Jones breaks down six powerful benefits of optimized testosterone and why restoring levels can dramatically improve quality of life as you age. Connect with Dr. Greg JonesInstagram: @doctorjones_doctorjones Enovative Wellness Center: https...

Biohacking promises longer life, sharper cognition, and faster recovery—but which strategies are actually supported by science? In this episode, Dr. Greg Jones sits down with Dr. Neil Paulvin, a New York–based, board-certified physician specializing in longevity and regenerative medicine, to separate evidence-based optimization from internet hype. Known as “the peptide doc,” Dr. Paulvin explains w...

True wellness isn’t about chasing symptoms—it’s about understanding the internal communication systems that allow the body to repair, adapt, and thrive. In this episode, Dr. Greg Jones is joined by Dr. Kathleen O’Neil-Smith, a Harvard-trained physician and pioneer in peptide therapy, to explore how peptides, mitochondria, and personalized medicine work together to support resilient, long-term heal...

The legal landscape for peptide therapy is changing. In this episode, Dr. Greg Jones talks with healthcare attorney Jeff Cohen about recent regulatory updates and their implications for providers. Jeff explains the risks of using "Research Use Only" products in a clinical setting and how to properly verify your suppliers' quality and safety.  You will learn why it is important to focus on educatio...

In this episode, Dr. Greg Jones welcomes back Kim Look to explore the cutting-edge landscape of EBOO (Extracorporeal Blood Oxygenation and Ozonation) . While many are familiar with traditional ozone therapy, EBOO represents a significant evolution, enabling the treatment of much larger volumes of blood through a sophisticated filtration and gas exchange system. Kim breaks down the "same but d...

Leaky gut is a major driver of inflammation, autoimmune issues, and chronic digestive symptoms. In this video, you’ll learn what leaky gut really is and how three powerful peptides—BPC-157, KPV, and Larazotide—can support gut repair, reduce inflammation, and strengthen the intestinal barrier. Perfect for anyone exploring advanced gut-healing tools. CHAPTERS00:00 What Leaky Gut Is and Why It Matter...

In this episode, Dr. Greg Jones sits down with Dr. Sharon Hausman-Cohen, Chief Medical Officer of IntelliXX DNA, to explore how medical genomics is transforming the way we understand heart disease, brain health, inflammation, and metabolism. Most people think genetics stops at traits like eye color or ancestry. Genomics goes much deeper—analyzing how thousands of genes interact to influence cardio...

Dr. Jones dives into the world of MOTS-C, explaining its potential to enhance metabolic health. He highlights its role in peptide therapy to optimize healing and promote fat loss. This biohacking approach could be a key to longevity science and overall health. CHAPTERS00:00 What MOTS-c Is & Why It’s Unique00:37 How MOTS-c Works in the Cell01:12 Mitochondrial Benefits & Energy Support02:18...

Platelet-Rich Plasma (PRP) is everywhere—but why does it help some patients and completely fail for others? In this episode, Dr. Greg Jones sits down with Dr. Joe Albano, a nationally recognized expert in regenerative orthopedics, to break down why not all PRP is created equal . They explore the real reasons PRP fails, including missed diagnoses, incorrect platelet dosing, poor patient preparation...

Dr. Jones discusses using innovative therapies for patient healing, specifically noting benefits like reduced inflammation and boosted hair growth. He highlights the science behind GHK-Cu, especially its positive effects on skin care and collagen synthesis. Learn more about how GHK-Cu enhances skin. CHAPTERS00:00 Introduction to GHK Copper00:46 What Is GHK Copper and How It Works01:34 Skin Health...

The bicarbonate buffer system plays a critical role in the body’s ability to maintain pH, manage inflammation, and support cellular healing—and in this episode, Dr. Greg Jones sits down with Dr. Mark Sircus to explore how restoring this natural bicarbonate buffering system may help slow aging and support the body’s capacity to heal chronic disease. Drawing from decades of clinical experience, Dr....

Dr. Jones clarifies how the combination of CJC-1295 and Ipamorelin can enhance growth hormone production and release. He elucidates the science in this peptides explained video, highlighting the potential health benefits his patients have experienced with ipamorelin and peptide therapy. Understand how these growth hormone-stimulating compounds work together. CHAPTERS00:00 What Are CJC-1295 and Ipa...

Therapeutic Plasma Exchange (TPE) has quickly become one of the most discussed longevity tools, bridging traditional medicine with cutting-edge regenerative therapies. In this episode, Dr. Greg Jones sits down with Dr. John Layke—Beverly Hills plastic surgeon and leading longevity physician—to unpack the science, clinical applications, and real-world results behind TPE.  Dr. Layke explains how TPE...

Discover how peptides work, what they can help with, and why they’re becoming one of the most powerful tools in functional and regenerative medicine. Dr. Greg Jones breaks down peptide safety, how they signal the body, the top peptides for weight loss, healing, cognition, immunity, and longevity — plus the different delivery methods like injections, oral options, nasal sprays, IVs, and topicals. C...

In this episode, Dr. Jones is joined by Dr. Donald Layman, one of the world’s top experts in protein metabolism. They discuss what happens to our muscles as we age, why leucine is a key amino acid for building and repairing muscle, and the amount of protein needed to stay strong and healthy. Dr. Layman also explains the differences between lifespan, longevity, and health span — and how muscle help...

In this episode, Dr. Greg Jones is joined by Dr. Tori Hudson, a naturopathic physician, educator, and one of the most respected voices in women’s health. With more than 40 years of experience, Dr. Hudson shares how women can better understand and support their hormones from puberty through menopause. They talk about everything from PMS and birth control to perimenopause, menopause, and the recent...