New Era in Obesity Drug Development

Obesity is a serious, chronic disease with multiple health consequences. Effective treatment should go beyond simply reducing body weight. It must focus on decreasing fat mass, improving body composition including preserving muscle mass and enhancing muscle quality addressing associated metabolic comorbidities, and ultimately improving overall quality of life. Today, scientific advances highlighte...

In this episode, we hear from Sarah, a patient living with obesity and a passionate advocate, as she shares her personal experience participating in clinical trials. Sarah reflects on the emotional and practical motivations that drive patients to join studies—from the hope of accessing new treatments to the desire to contribute to scientific progress. She emphasizes the importance of transparency,...

In this episode, we hear from Sarah, a patient living with obesity, as she shares her lifelong journey—from early body image struggles and restrictive dieting to participating in a televised weight-loss transformation. Despite achieving peak fitness and completing an Olympic triathlon, Sarah’s weight returned, prompting her to explore the science behind obesity. Her discovery of metabolic adaptati...