Multiple Chronic Conditions in Research for Emerging Investigators

Join Dr. Jerry Gurwitz, from UMass Chan Medical School and UMass Memorial Medical Center, and Drs. Namrata Singh from University of Washington, Melissa Loh from the University of Rochester, and Rasheeda Hall from Duke University, as they highlight opportunities for rheumatology, oncology, and nephrology specialists to implement MCC Care.  To view a transcript click here then select the transcript...

Join Cynthia Boyd, MD, MPH, John Hopkins Medicine, and Arlene Bierman, MD, MS, AHRQ’s Center for Evidence and Practice Improvement and Rafael Samper-Ternent, MD, PhD, UT Health Houston as they discuss policy challenges and clinical care in relation to MCCs and aging, as well as knowledge gaps and areas to be improved. To view a transcript click here then select the transcript tab.

Join Jay Magaziner, PhD, University of Maryland School of Medicine; and Stephanie Studenski, MD, University of Pittsburgh School of Medicine & National Institute on Aging; Luigi Ferrucci, MD, PhD, National Institute on Aging and Rafael Samper-Ternent, MD, PhD, UT Health Houston as they discuss important epidemiological and biological aspects of MCCs and aging, as well as, some knowledge gaps,...

Join Jeff Williamson, MD, MHS, Wake Forest University School of Medicine, and Kathryn Callahan, MD, MS, Wake Forest University School of Medicine, as they discuss health system coalition building and the different kinds of skillsets of team members in the Learning Healthcare System (LHS). They also discuss implementing initiatives in an LHS. To view a transcript click here then select the transcri...

Join Leah Hanson, PhD, HealthPartners Institute and Tullika Garg, MD, MPH, Penn State Health Milton S. Hershey Medical Center, as they discuss how clinical gaps play a role in practice and initiating research. They examine the different perspectives and roles of the patient, clinician, clinical staff and leadership in identifying those clinical gaps. They also consider barriers faced when trying t...

Join Jeff Williamson, MD, MHS, Wake Forest University School of Medicine, and Leah Hanson, PhD, HealthPartners Institute, as they discuss learning healthcare systems (LHS) and their potential value. They define LHS, their importance and also the differences in the cycle of research in the LHS vs the traditional academic research study. To view a transcript click here then select the transcript tab...

Join Terrence E. Murphy, PhD, MS, Pennsylvania State University College of Medicine, and Qian-Li Xue, PhD, Johns Hopkins Bloomberg School of Public Health, as they discuss missing data. They review different types of missing data mechanisms, analytic approaches to approach missing data and good practice with missing data. To view a transcript click here then select the transcript tab.

Join Terrence E. Murphy, PhD, MS, Pennsylvania State University College of Medicine, and Karen Bandeen-Roche, PhD, Johns Hopkins Bloomberg School of Public Health, as they discuss usefulness of cluster analysis for the study of multimorbidity. To view a transcript click here then select the transcript tab.

Join Karen Bandeen-Roche, PhD, Johns Hopkins Bloomberg School of Public Health, and Ravi Varadhan, PhD, John Hopkins University, as they discuss the challenges and limitations of randomized clinical trials, and observational data for providing evidence relevant to older adults with multimorbidity. They review a cross-design synthetic approach combining trials and real-world data to generate eviden...

Join Karen Bandeen-Roche, PhD, Johns Hopkins Bloomberg School of Public Health, and Terrence E. Murphy, PhD, MS, Pennsylvania State University College of Medicine, as they discuss predictive risk modeling in the context of multimorbidity. They discuss the importance of model selection depending on the situation. They also discuss internal and external validation, statistical modeling and outcome e...

Join Terrence E. Murphy, PhD, MS, Pennsylvania State University College of Medicine, and Kendra Plourde, PhD, Yale School of Medicine, as they discuss joint modeling methods. They also discuss longitudinal models, modeling survival events, collider bias and the many types and useful applications of joint models. To view a transcript click here then select the transcript tab.

Join Alyce Adams, PhD, Stanford University, Libby Hoy, BS, Patient-Centered Outcomes Research Institute and Patricia Rodriguez Espinosa, PhD, MPH, Stanford University as they discuss engaging patients, caregivers and communities in research, methods to evaluate success and impact and the state of research and future for engagement. This podcast will discuss each topic covered in the Patient, Famil...

Join moderator Dr. Heather Whitson from Duke University School of Medicine to talk about Tools, Strategies, and Approaches to Improve Inclusion Across the Lifespan in Multiple Chronic Conditions Research with panelists, Maya Clark-Cutaia, PhD, ACNP-BC, from NYU, Hanzhang Xu, PhD, RN from Duke University School of Medicine and Barrett Bowling, MD from, Duke University School of Medicine. They also...

Join Dr. Ana Quiñones, from Oregon Health & Science University, and Darina V. Petrovsky, PhD, RN from Rutgers University; Jane Jih, MD, MPH, MAS from UCSF; Elizabeth Eckstrom, MD, MPH from Oregon Health & Science University and Karen M. Goldstein, MD, MSPH from Durham VA Health Care System, to discuss why inclusion is so important in research and how inclusion will improve health equity ov...

Join Dr. Heather Whitson, from Duke University School of Medicine and Dr. Cathleen Colon-Emeric, from Duke University School of Medicine, as they explore ways to find and sustain career success and satisfaction. They also discuss describe challenges and strategies for success in research on multiple chronic conditions (MCCs) in developing your team, research program and a personalized professional...

Join Dr. Albert Siu, from Icahn School of Medicine at Mount Sinai, and Dr. Heather Whitson, Duke University School of Medicine, as they discuss dissemination of MCCs findings and translating them into practice change, policy, and better outcomes. They touch upon the specific dissemination and implementation barriers that exist for interventions to manage multiple chronic conditions (MCCs) and hybr...

Join Dr. Heather Whitson, from Duke University School of Medicine, and Dr. Albert Siu, from Icahn School of Medicine at Mt. Sinai, to discuss ways to foster an effective team for multimorbidity research. The pair also define an ideal team, with real-world relevance to your MCC research agenda and strategies that support effective interdisciplinary teams.  To view a transcript click here then selec...

Join Dr. Heather Allore, from Yale School of Medicine and Dr. David Reuben, from University of California, Los Angeles, as they delineate between explanatory and pragmatic trials and discuss issues to consider when conducting pragmatic trials in health care systems, including commitment to supporting clinical personnel, study infrastructure, and fidelity.  To view a transcript click here then sele...

Join Dr. David Reuben, from University of California, Los Angeles, and Dr. Subashan Perera, from the University of Pittsburg School of Medicine, as they discuss cluster randomized trials. They touch upon the main characteristics, statistical advantages, and disadvantages, and potential ethical or operational issues of conducting these types of trials.    To view a transcript click here then select...

Join Dr. Mike Steinman, from the University of California, San Francisco and Abigail Baim-Lance, PhD, from the Icahn School of Medicine at Mount Sinai, as they discuss how existing procedures for serious and non-serious adverse events (SAEs/AEs) are not always appropriate for clinical research involving older adults with serious illness. They also explore an alternative approach to defining, monit...

Join Dr. Sarah Berry and Junhong Zhou, PhD, from Harvard Medical School, as they review the characteristics of novel digital tools to measure functions in older adults with multimorbidity, while underscoring both the advantages and challenges of using these digital technologies in measurement. To view a transcript click here then select the transcript tab. 

Join Dr. Sarah Berry Harvard Medical School and Michelle Xue, PhD-c, RN, nurse scientist and doctoral candidate at the Duke University School of Nursing, as they discuss the similarities and differences between person-centered outcomes and patient-reported outcomes and touch on how to apply person-centered approaches and measures in both clinical settings and research. To view a transcript click h...

Join Dr. Michael Steinman, from the University of California, San Francisco and Dr. Greg Ouellet, Assistant Professor at the Yale School of Medicine and the VA Connecticut in West Haven, as they define universal outcomes in contrast with disease-specific outcomes and explain why the former are particularly helpful when studying older adults with multiple chronic conditions. They also delineate bet...

Join Dr. Heather Allore, from Yale School of Medicine and Professor Basia Diug, from Monash University School of Public Health and Preventive Medicine (Melbourne, Australia), to discuss the role of observational studies in multimorbidity research. The pair also define and provide examples of several categories of observational studies, while examining the strengths and limitations of these designs...

Join Dr. Michael Steinman, from the University of California, San Francisco and Dr. Rebecca Brown, from the University of Pennsylvania Perelman School of Medicine, as they define multimorbidity, frailty, and functional status as three important syndromes in geriatrics that influence health status and quality of life for older adults. Find out more about how these syndromes intersect and their impl...