A J Ghalayini, Ph.D.

Metabolism Made Easy

This podcast describes selected biochemistry content that could be useful to premedical/medical students. Similar content (podcasts and videos) is available at:https://medbiochem.org/Check out my podcast on YouTube below:https://youtube.com/playlist?list=PLXy2KYiCd9rlg0JmfA392WrEiOYNu39xn&si=Nu2LkpYOjHPZpxd5These podcasts and videos cover selected topics in medical biochemistry. A J Ghalayini, Ph. D.Bio for Dr. Ghalayini:Dr. Ghalayini received his Ph. D. in Biochemistry from the Universi

Author

A J Ghalayini, Ph.D.

Category

Education

Podcast website

medbiochem.org

Latest episode

Jul 8, 2026

Where to listen?

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Episodes

Digestion, Reassembly, Absorption, and Storage of Dietary Triacylglycerol 08.12.2022

This podcast describes the digestion, reassembly, absorption and storage of dietary Triacylglycerol including the role of pancreatic lipase and lipoprotein lipase. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

FASTING, Glucagon and Liver Glucose Ouput 25.11.2022

This podcast describes the liver output of glucose during fasting and its regulation by glucagon. Similar content is available at: MEDBIOCHEM.ORG

Covalent Modification of Enzymes 16.11.2022

This podcast covers the phosphorylation of enzymes by protein kinases that modify specific hydroxyl residues in enzymes. This content may be useful to premedical and medical students. Similar biochemistry content is available at: MEDBIOCHEM.ORG

Reduction of Plasma Cholesterol by Statins 15.09.2022

This podcast describes the specific mechanism by which statins reduce plasma cholesterol. The reduction of cholesterol synthesis by statins in effect, will result in the upregulation of the LDL receptor and increased uptake of LDL from plasma. Similar content is available at: MEDBIOCHEM.ORG

Insulin Effects on Liver, Muscle and Adipose Tissue 15.09.2022

This podcast describes the specific metabolic effects of insulin on liver, muscle and adipose tissue. Similar content is available at: MEDBIOCHEM.ORG

Adenylate Cyclase: 7 Key Features 03.09.2022

This podcast covers the key components of the adenylate cyclase system including receptor activation, G-protein involved, activation of adenylate cyclase , production of cAMP, activation of PKA and termination of the actions of cAMP . Also included is a historical perspective of the discovery of G-proteins the adeylate cyclase system.

Reversal of PKA Effects by Insulin 01.09.2022

This podcast describes the activation of the a phosphoprotein phosphatase by insulin. Also check out the podcast below for insulin's effects on specific enzymes: https://anchor.fm/a-j-ghalayini/episodes/Insulin-and-Enzyme-Dephosphorylation-e1mb74a

Phosphorylation of Key Enzymes by PKA and AMP kinase 01.09.2022

This podcast covers key enzymes in carbohydrate and lipid metabolism the are phosphorylated by either PKA or AMP kinase and the outcome of phosphorylation on enzyme activity. Also check out the podcast on Adenylate Cyclase below: https://anchor.fm/a-j-ghalayini/episodes/Adenylate-Cyclase-7-Key-Features-e1nb35t

Cortisol and Inflammation 10.08.2022

This podcast describes the effect of cortisol on eicosanoid biosynthesis and its resulting anti-inflammatory effects. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Insulin and Enzyme Dephosphorylation 10.08.2022

This podcast describes the outcome of dephosphorylation of key enzymes trigerred by Insulin binding to its receptor and resulting in changes of both carbohydrate and lipid metabolism. Also check out my Insulin playlist on YouTube below for additional videos: INSULIN: https://www.youtube.com/playlist?list=PLXy2KYiCd9rlWs3TxwuMk26ncmzva3PM3. This biochemistry content may be useful to premedical and...

Phospholipase C. 6 Key Features 08.07.2022

This podcast covers in the detail the actions of phospholipase C starting with receptor activation, activation of Gq, production of second messengers and activation of PKC. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG Biochemistry by Metabolism Made Easy playlist on YouTube: https://www.youtube.com/playlist?list=PLXy2KY...

2 Enzymes that Require Vitamin B12 08.05.2022

This podcast covers the only 2 enzymes that require Vitamin B12 . This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Thiamine Requirement: 4 Key Enzymes 31.03.2022

This podcast covers the 4 enzymes requiring thiamine as a coenzyme. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Carbon Skeletons: Glucogenic vs. Ketogenic 25.02.2022

This podcast covers the carbon skeletons derived from amino acids and their classification as glucogenic or ketogenic. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

NADPH: Sources and Uses 17.02.2022

This podcast describes the major sources of NADPH and its primary uses in 5 biological reactions. This content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Malonyl CoA: Regulation of fatty acid synthesis and beta oxidation 28.01.2022

This podcast covers the regulation of acetyl CoA Carboxylase allosterically and by covalent modification. The effect of malonyl CoA on beta oxidation of fatty acids is also described. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Acetyl CoA: Sources and Fates 19.12.2021

This podcast describes the molecules that can produce acetyl CoA as well as the possible metabolic fates of acetyl CoA. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Metabolism: An Overview 12.12.2021

This podcast is an overview of the components of metabolism, namely, catabolism and anabolism and their respective cellular functions. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Purine Salvage: HGPRT and Hyperuricemia 16.11.2021

This podcast covers the purine salvage pathway and the inherited deficiency in the salvage of hypoxanthine and guanine (HGPRT) and its outcome in infants. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG.

Glycolysis vs. Gluconeogenesis: A Futile Cycle? 10.11.2021

This podcast covers the mutual regulation of glycolysis and gluconeogenesis by allosteric regulators, thus preventing the likelihood of a futile cycle from occurring. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Insulin Resistance III: Dyslipidemia 04.11.2021

This podcast describes the underlying changes associated with insulin resistance and resulting in dyslipidemia. These changes include effects on two key lipases namely, Lipoprotein Lipase and Hormone-Sensitive Lipase. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Insulin Resistance II: Hyperglycemia 01.11.2021

This podcast describes one of the key outcomes of insulin resistance, hyperglycemia, including the specific tissue contributions to the rise in plasma glucose. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Insulin Resistance I: Behind The Scene 29.10.2021

This podcast describes the underlying changes associated with insulin resistance and its consequences in both plasma and target tissues. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Biosynthesis of non-essential amino acids: Summary 27.10.2021

This podcast is a summary of the biosynthesis of non-essential amino acids from their respective carbon skeletons. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

The Pancreas and Insulin Secretion 23.10.2021

This podcast describes the signals for insulin secretion by the pancreas and the molecular mechanism behind its secretion by the islets of Langerhans beta cells. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

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