Metabolism Made Easy

This podcast covers the carbon skeletons derived from amino acids and their classification as glucogenic or ketogenic. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes the major sources of NADPH and its primary uses in 5 biological reactions. This content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast covers the regulation of acetyl CoA Carboxylase allosterically and by covalent modification. The effect of malonyl CoA on beta oxidation of fatty acids is also described. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes the molecules that can produce acetyl CoA as well as the possible metabolic fates of acetyl CoA. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast is an overview of the components of metabolism, namely, catabolism and anabolism and their respective cellular functions. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast covers the purine salvage pathway and the inherited deficiency in the salvage of hypoxanthine and guanine (HGPRT) and its outcome in infants. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG.

This podcast covers the mutual regulation of glycolysis and gluconeogenesis by allosteric regulators, thus preventing the likelihood of a futile cycle from occurring. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes the underlying changes associated with insulin resistance and resulting in dyslipidemia. These changes include effects on two key lipases namely, Lipoprotein Lipase and Hormone-Sensitive Lipase. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes one of the key outcomes of insulin resistance, hyperglycemia, including the specific tissue contributions to the rise in plasma glucose. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes the underlying changes associated with insulin resistance and its consequences in both plasma and target tissues. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast is a summary of the biosynthesis of non-essential amino acids from their respective carbon skeletons. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes the signals for insulin secretion by the pancreas and the molecular mechanism behind its secretion by the islets of Langerhans beta cells. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes the role of cytosolic citrate in regulating glycolysis, fatty acid synthesis and providing thd vehicle to transport Acetyl CoA to the cytoplasm where it is needed for lipid synthesis. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast covers the fifth unique liver function in its ability to detoxify organic molecules by making them more water soluble. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes the role of the Urea cycle in detoxifying ammonia as the fifth unique function of the liver. This biochemistry content may be useful to premedical and medical students. Similar content is available at:MEDBIOCHEM.ORG

This podcast describes the unique ability of the liver to synthesize ketone bodies in the mitochondria from Acetyl CoA during fasting. The ketone bodies thus produced can provide an alternative energy source to multiple peripheral tissue including the brain, but excluding the liver. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOC...

This podcast describes the second unique role of the liver in cholesterol biosynthesis, storage and uptake of LDL from plasma. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG Check out my YouTube playlist:https://youtube.com/playlist?list=PLXy2KYiCd9rlg0JmfA392WrEiOYNu39xn

This podcast describes the unique function of the liver in producing glucose during fasting. The liver restores blood glucose through two coordinated processes, glycogenolysis and gluconeogenesis. The podcast also covers the key regulation of both processes by glucagon/epinephrine. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCH...

This podcast covers 5 unique functions that are either exclusive to the liver, or occur mostly in the liver. These functions include: glucose production, cholesterol synthesis, ketone bodies synthesis, the Urea cycle and detoxification of organic molecules. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes the key features of hormone-sensirive lipase and its activation by the beta-adrenergic receptor in adipose tissue during fasting. This biochemistry content may be useful to premedical and medical students. Similar content is available at:MEDBIOCHEM.ORG or check out my YouTube channel Metabolism Made Easy: https://youtube.com/playlist?list=PLXy2KYiCd9rlg0JmfA392WrEiOYNu39xn

This podcast covers 3 key features of Lipoprotein Lipase including its location, unique function and upregulation by insulin. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

This podcast describes the mechanism of action of Statins and how they are able to reduce plasma cholesterol. This biochemistry content may be useful to premedical and medical students.

This podcast describes the role of glutamine in detoxifying ammonia produced in peripheral tissues and its transport in the bloodstream for further metabolism and/or disposal of ammonia. This biochemistry content may be useful to premedical and medical students. Similar content is available at:MEDBIOCHEM.ORG

This pocast covers the metabolism of alanine, glutamate and aspartate and the carbon skeletons they produce, in addition to their input of nitrogen to the Urea cycle. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG. You can check out my playlist on YouTube for additional videos. Metabolism Made Easy: https://www.youtube.co...

This podcast describes the sources of nitrogen that enter the Urea cycle including the role of 3 enzymes (ALT, AST, GDH) in collecting nitrogen from amino acid metabolism. The role of Glutamate as a sink for nitrogen is also covered. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG or YouTube channel: Metabolism Made Easy.