A J Ghalayini, Ph.D.

Metabolism Made Easy

This podcast describes selected biochemistry content that could be useful to premedical/medical students. Similar content (podcasts and videos) is available at:https://medbiochem.org/Check out my podcast on YouTube below:https://youtube.com/playlist?list=PLXy2KYiCd9rlg0JmfA392WrEiOYNu39xn&si=Nu2LkpYOjHPZpxd5These podcasts and videos cover selected topics in medical biochemistry. A J Ghalayini, Ph. D.Bio for Dr. Ghalayini:Dr. Ghalayini received his Ph. D. in Biochemistry from the Universi

Author

A J Ghalayini, Ph.D.

Category

Education

Podcast website

medbiochem.org

Latest episode

Jul 8, 2026

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Episodes

Citrate: A Master Regulator 22.10.2021

This podcast describes the role of cytosolic citrate in regulating glycolysis, fatty acid synthesis and providing thd vehicle to transport Acetyl CoA to the cytoplasm where it is needed for lipid synthesis. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

The LIVER: Detoxifying Organic Molecules 19.10.2021

This podcast covers the fifth unique liver function in its ability to detoxify organic molecules by making them more water soluble. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

The LIVER: Detoxifying Ammonia: Role of UREA 14.10.2021

This podcast describes the role of the Urea cycle in detoxifying ammonia as the fifth unique function of the liver. This biochemistry content may be useful to premedical and medical students. Similar content is available at:MEDBIOCHEM.ORG

The LIVER: Altruistic Ketogenesis 11.10.2021

This podcast describes the unique ability of the liver to synthesize ketone bodies in the mitochondria from Acetyl CoA during fasting. The ketone bodies thus produced can provide an alternative energy source to multiple peripheral tissue including the brain, but excluding the liver. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOC...

The LIVER: Cholesterol Central 08.10.2021

This podcast describes the second unique role of the liver in cholesterol biosynthesis, storage and uptake of LDL from plasma. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG Check out my YouTube playlist:https://youtube.com/playlist?list=PLXy2KYiCd9rlg0JmfA392WrEiOYNu39xn

The LIVER: A Glucose Factory 06.10.2021

This podcast describes the unique function of the liver in producing glucose during fasting. The liver restores blood glucose through two coordinated processes, glycogenolysis and gluconeogenesis. The podcast also covers the key regulation of both processes by glucagon/epinephrine. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCH...

The LIVER: 5 Unique Functions 04.10.2021

This podcast covers 5 unique functions that are either exclusive to the liver, or occur mostly in the liver. These functions include: glucose production, cholesterol synthesis, ketone bodies synthesis, the Urea cycle and detoxification of organic molecules. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Hormone-Sensitive Lipase: 3 Key Features 03.10.2021

This podcast describes the key features of hormone-sensirive lipase and its activation by the beta-adrenergic receptor in adipose tissue during fasting. This biochemistry content may be useful to premedical and medical students. Similar content is available at:MEDBIOCHEM.ORG or check out my YouTube channel Metabolism Made Easy: https://youtube.com/playlist?list=PLXy2KYiCd9rlg0JmfA392WrEiOYNu39xn

Lipoprotein Lipase: 3 Key Features 02.10.2021

This podcast covers 3 key features of Lipoprotein Lipase including its location, unique function and upregulation by insulin. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Cholesterol biosynthesis III: Statins 01.10.2021

This podcast describes the mechanism of action of Statins and how they are able to reduce plasma cholesterol. This biochemistry content may be useful to premedical and medical students.

Detoxifying Ammonia: Role of GLUTAMINE 01.10.2021

This podcast describes the role of glutamine in detoxifying ammonia produced in peripheral tissues and its transport in the bloodstream for further metabolism and/or disposal of ammonia. This biochemistry content may be useful to premedical and medical students. Similar content is available at:MEDBIOCHEM.ORG

Three Amino Acids:Three Carbon Skeletons 29.09.2021

This pocast covers the metabolism of alanine, glutamate and aspartate and the carbon skeletons they produce, in addition to their input of nitrogen to the Urea cycle. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG. You can check out my playlist on YouTube for additional videos. Metabolism Made Easy: https://www.youtube.co...

Nitrogen input to the Urea cycle: Role of Glutamate 28.09.2021

This podcast describes the sources of nitrogen that enter the Urea cycle including the role of 3 enzymes (ALT, AST, GDH) in collecting nitrogen from amino acid metabolism. The role of Glutamate as a sink for nitrogen is also covered. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG or YouTube channel: Metabolism Made Easy.

Methionine and the Vitamin B12 Trap 25.09.2021

This podcast describes some of the key features of the essential amino acid methionine, as well as, the role of vitamin B12 and folic acid in its resynthesis from homocysteine. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Protein degradation II: Amino acid carbon skeletons 25.09.2021

This podcast defines and describes the use of ketogenic and glucogenic carbon skeletons derived from amino acids. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG or Check out my YouTube channel: Metabolism Made Easy.

Can glucose be made from Fat? 23.09.2021

This podcasts explains why glucose cannot be made from fatty acid beta oxidation products i.e. Acetyl CoA. Exceptions to this concept are also included. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Protein degradation I: An overview 23.09.2021

This podcast describes protein degradation and some of the signals that target cellular proteins for proteolysis. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

LIPASES: Location, location, location 20.09.2021

This podcast describes 4 types of important lipases with unique locations and functions. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Nucleotides and Chemotherapy: An overview 08.09.2021

This podcast covers the strategy of targeting 3 enzymes in nucleotide biosynthesis by chemotherapy drugs. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Triacylglycerol: You are what you eat! 04.09.2021

This podcast describes the composition, digestion and reassembly of triacylglycerol from the diet. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

CREATING an effective presentation: Less is more 03.09.2021

This podcast provides a simple approach for creating and organizing an effective in class or online presentation.

Insulin and Glucagon Metabolic Effects 02.09.2021

This podcast describes the key metabolic effects of insulin and glucagon in various tissues. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Eicosanoids and Inflammation 31.08.2021

This podcast describes the synthesis of eicosanoids from arachidonic acid as well as their key roles in inflammation. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Eicosanoids: Leukotrienes 31.08.2021

This podcast describes the synthesis of leukotrienes from arachidonic acid and their role in hypersensitivity reactions. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG

Omega-6 vs Omega-3 Eicosanoids 31.08.2021

This podcast describes the two different eicosanoids derived from linoleic acid and linolenic acid, respectively and their relative effects in in the inflammatory response. Similar content is available at: MEDBIOCHEM.ORG

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