Chris Masterjohn, PhD
Mastering Nutrition
Welcome to the Mastering Nutrition podcast. Mastering Nutrition is hosted by Chris Masterjohn, a nutrition scientist focused on optimizing mitochondrial health, and founder of BioOptHealth, a program that uses whole genome sequencing, a comprehensive suite of biochemical data, cutting-edge research and deep scientific insights to optimize each person's metabolism by finding their own unique unlocks. He received his PhD in Nutritional Sciences from University of Connecticut at Storrs in 2012, served as a postdoctoral research associate in the Comparative Biosciences department of the University...
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Chris Masterjohn, PhD
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Latest episode
Dec 15, 2025
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Episodes
What type and how much psyllium to lower LDL-cholesterol? | Masterjohn Q&A Files #276 13.09.2021 10:59
Short answer: 15 grams of psyllium husk should lower LDL-C over 6 weeks, and you may be able to get away with cutting the dose down to 5-10 grams if using a fine powder. Watch the video or listen to the podcast with the links below. You can obtain a full transcript of the episode by signing up for the Masterpass at https://chrismasterjohnphd.com/q&a Please consider supporting my work by making a p...
What is the most sustainable way to implement carb cycling? | Masterjohn Q&A Files #275 10.09.2021 14:08
Short answer: When trying to stop the early progression of insulin resistance, it is best to use a combination of strength, power and muscle building, fat loss, and high-intensity exercise in 20-second to one-minute bouts; to institute a rhythmic fasting-feeding cycle; and not to use berberine or metformin unless absolutely needed. One good way to integrate these is to use an "earn your carbs" app...
Do fat and carbs differ in how much energy they yield? | Masterjohn Q&A Files #274 08.09.2021 11:08
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Should green tea be taken with meals and can it hurt nutrient absorption? | Masterjohn Q&A Files #273 07.09.2021 5:30
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Why does methylfolate act as the off-switch for the glycine buffer system? | Masterjohn Q&A Files #272 06.09.2021 10:19
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Vitamin D and COVID-19: The Current State of the Evidence 03.09.2021 1:03
Here is my comprehensive review of the literature to date, covering 98 observational studies, 6 randomized controlled trials, with 173 references: chrismasterjohnphd.com/vitamind This is a topic we can't afford to ignore! Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome
How to get by on poor sleep? | Masterjohn Q&A Files #271 03.09.2021 6:24
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Across what timeframe should we diversify foods? | Masterjohn Q&A Files #270 02.09.2021 7:45
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Nutrition For Bone Healing | Masterjohn Q&A Files #269 01.09.2021 9:46
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
What tests to use for protein status? | Masterjohn Q&A Files #268 31.08.2021 10:14
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Is nicotinamide riboside hydrogen malate as good as NR for fasting? | Masterjohn Q&A Files #267 30.08.2021 17:03
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Would high-dose thiamin cause imbalances with other B vitamins? | Masterjohn Q&A Files #266 27.08.2021 4:23
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Why does B12 damaged by nitrous oxide require megadosed folic acid rather than normal levels of folate? | Masterjohn Q&A Files #265 26.08.2021 17:51
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Nutrition, Metformin, and Respiratory Chain Disorders | Masterjohn Q&A Files #264 25.08.2021 20:01
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Why do some paleo advocates and functional medicine practitioners recommend low-calcium diets? | Masterjohn Q&A Files #263 24.08.2021 16:02
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
How should you program the temperature on an Ooler or Eight Sleep? | Masterjohn Q&A Files #262 23.08.2021 5:49
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Is it useful to measure HVA, VMA, and 5-HIAA? | Masterjohn Q&A Files #261 20.08.2021 5:01
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
What nutrients require insulin to get into cells? | Masterjohn Q&A Files #260 19.08.2021 4:52
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
What are the top whole food supplements to take? | Masterjohn Q&A Files #259 18.08.2021 3:39
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Could iron deficiency create a complex 1 disorder? | Masterjohn Q&A Files #258 17.08.2021 4:15
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
How to get more sulfate if you have sulfite issues? | Masterjohn Q&A Files #257 16.08.2021 12:41
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
If you're eating oysters, do you need to eat liver too? | Masterjohn Q&A Files #256 13.08.2021 6:59
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Lipoic acid: does it need to be the R form? | Masterjohn Q&A Files #255 12.08.2021 4:27
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
How much fruit is it safe to eat at once? | Masterjohn Q&A Files #254 11.08.2021 4:03
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
Should I supplement NAC if cysteine, taurine, and sulfate are low? | Masterjohn Q&A Files #253 10.08.2021 4:48
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic , https://chrismasterjohnphd.com/paleovalley , https://chrismasterjohnphd.com/seekinghealth , https://chrismasterjohnphd.com/ancestralsupplements , https://chrismasterjohnphd.com/magicspoon , https://chrismasterjohnphd.com/lmnt Plenty more at https://chrism...
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