Journal of the American Society of Nephrology (JASN)

Dr. Briggs and Brendon Neuen discuss his paper in the December issue of JASN. This article on the CREDENCE and EMPA-CKD clinical trials shows that SGLT2 inhibitors allow more consistent use of RAS blockade in patients with declining renal function.

In this podcast, EIC Josie Briggs talks with Associate Editor John Gill about the valuable data resources for research on kidney transplantation. Drs. Gill and Briggs provide some advice for users of these important resources.

In this podcast, EIC Josie Briggs talks with Giuseppe Remuzzi about the NEPHSTROM Trial & the next steps in translational work to test the possibility that mesenchymal stem cells can be used as a therapeutic agent to promote repair of kidney damage.

In the podcast, EIC Josie Briggs discusses a paper entitled "Structural Racism, Historical Redlining, and Incidence of Kidney Failure in US Cities" with co-authors Kevin Nguyen and Deidre Crews.

In the episode, EIC Josie Briggs discusses a randomized control trial addressing the impact of sodium bicarbonate on the vascular dysfunction in CKD and an observational case control study of the impact of antibiotic use on kidney stone formation.

In this podcast, Dr. Josie Briggs discusses with Dr. Andrew Rule his latest study showing the need to revise our estimate of the number of nephrons in the human kidney.

In this episode, JASN Associate Editor Katalin Susztak talks with Dr. Susan Quaggin about work from her laboratory on ischemic injury and translational targets in the Angiopoietin-Tie 2 pathway.

JASN EIC Josie Briggs talks with Deputy Editor Tom Hostetter about the unsolved problem of the chemical causes of the uremic syndrome. A new study reports a correlation of outcomes in CKD with protein carbamylation, a breakdown product of urea.

This podcast covers two papers, one describes a clinical workflow for incorporating whole exome sequencing and the other provides evidence genomic disorders contribute to monogenic CKD in adults and children.

In the March podcast, Dr. Briggs discusses a study that addresses prognostic measures in Anti-GBM Disease and a meta-analysis of studies testing whether intensive blood pressure controls slows progression of CKD.

In this Podcast, Dr. Briggs summarizes the goals of the new JASN Special Series, Health Policy Catalyst, and summarizes papers focusing on cost effectiveness research in nephrology and on the special risk of unwanted pregnancies for kidney patients.

In this podcast, Dr. Briggs discusses organoid studies with author Dr. Melissa Little. The work explores the varied molecular mechanisms of specific mutations that cause SRNS and suggests promise for eventual design of mutation-specific treatments.

In this podcast, EIC Dr Briggs discusses two studies on kidney transplantation with Dr. John Gill. Topics discussed include novel molecular markers and the role of HLA-DQ mismatches, work suggesting new approaches to reduce chronic graft loss.

In this podcast, EIC Josie Briggs talks with Lekha Tummalapalli about a study addressing costs of hemodialysis and peritoneal dialysis. An editorial on this issue is published in the November (33.11) issue of JASN.

In this podcast, JASN EIC, Josie Briggs talks with Juan-Jesus Carrero, Professor of Kidney Disease Epidemiology at Karolinska Institute. His study, published in the October issue of JASN, documents striking differences in care of men and women with CKD.

In this episode we cover two papers that examine the impact of climate change on nephrology practice. Specifically, the effect of extreme weather events on hemodialysis patient mortality and greenhouse gas emissions associated with dialysis treatment.

Two highlighted clinical studies: the first addresses the effect of combining a SGLT2 inhibitor and a MRA on proteinuria; the second considers vascular reactivity as a risk factor for cerebral hypoxia when blood pressure falls during dialysis treatments.

In this podcast, Dr. Briggs and JASN Deputy Editor, Dr. Donald Wesson discuss the special series highlighted in the July Issue. The series focuses on kidney health disparities with an emphasis on strategies for their elimination.

Dr. Briggs summarizes findings in a study published in the June issue of JASN. The study examines the impact of continued immunosuppression in patients with failed allografts; the effects are surprising and suggest current guidelines may not be optimum.

In this podcast Dr. Briggs talks with Dr. Kate Butler about advance care planning for patients with chronic kidney disease.

In the May 2022 JASN highlights, Dr. Briggs summarizes two important studies on the role of inflammation as a driving factor in the progression of CKD.

In this Podcast, JASN EIC, Josie Briggs, discusses a clinical trial from the April issue on roxadustat in dialysis patients with Magdalene Assimon. Dr. Assimon explains the interpretation of the finding that roxadustat is non-inferior to epoetin alpha.

Kidney patients are at high risk for cardiovascular disease. In this Podcast, Dr. Briggs talks and Dr. David Charytan discuss recent work to improve the prediction of CVD in kidney patients. New work from CRIC aims to update the Framingham equation.

In this episode, Dr. Josie Briggs and Dr. Brendon Neuen discuss the GFR paradox: SGLT inhibitors and other kidney-protective drugs initially cause a drop in GFR.

Josie Briggs talks with Nicholas Steers about his work using inbred mice strains to understand the genetic factors that result in collapsing focal segmental glomerulosclerosis in HIV nephropathy, insights also relevant to a rare complication of COVID-19