Johns Hopkins Medicine

Drugs to manage symptoms of Alzheimer’s disease may work in some people but not in others. Now a new method using brain organoids, which are derived from a person’s own blood sample, may help determine whether a specific medication is … Can drugs to manage Alzheimer’s disease be tested in organoids? Elizabeth Tracey reports Read More »

Brain organoids are lab grown clusters of cells that have several of the cell types found in someone’s brain. Cells taken from a person’s blood are coaxed to become stem cells, then differentiate into brain cells. Vasiliki Machairaki, a genetic … Can brain organoids help in treating people with Alzheimer’s disease? Elizabeth Tracey reports Read More »

Medicaid reductions being rolled out this year are poised to dramatically reduce cancer screening for millions, a new study estimates. William Nelson, director of the Kimmel Cancer Center at Johns Hopkins, takes a look at the numbers. Nelson: This is … Medicaid reductions may impact screening for cancer, Elizabeth Tracey reports Read More »

Breast cancer screening is associated with false positives, where women are referred for further assessments and procedures that may be unnecessary. Does it help to stratify women based on risk factors like genetics before they have screening? Johns Hopkins Kimmel … Should breast cancer screening be targeted to those at greatest risk? Elizabeth Tracey reports Read More »

People who were older and had advanced cancers benefited from a telephone-based intervention designed to regularly assess their symptoms and refer them to expert clinicians, by reducing their visits to emergency departments and need for hospitalization. Kimmel Cancer Center director … Can older people with cancer benefit from telephone based contact? Elizabeth Tracey reports Read More »

Seventy percent of people diagnosed with cancer in the United States will still be alive five years later, the American Cancer Society reports. William Nelson, director of the Kimmel Cancer Center at Johns Hopkins, says yes, and. Nelson: There's still … Good news on cancer survival! Elizabeth Tracey reports Read More »

American Cancer Society data find that the majority of people who are diagnosed with cancers of all types will still be alive five years later. Johns Hopkins Kimmel Cancer Center director William Nelson says this is good news indeed. Nelson: … There’s good news regarding survival when cancer if found, Elizabeth Tracey reports Read More »

Sleep is foundational to good health, but many people aren’t getting enough. In this episode of Medicine Made General, Dr. Charlene Gamaldo breaks down sleep – how much do adults really need, the consequences of chronic sleep deprivation, and separating … Ep 10. Sleep: The Other Vital Sign | Medicine Made General Read More »

PICS stands for post intensive care syndrome, and it is characterized by a number of physical and mental health conditions that may follow someone’s stay in an ICU. Rohan Mathur, a critical care expert at Johns Hopkins, says fatigue, memory … Who is at risk to develop PICS? Elizabeth Tracey reports Read More »

Physical and mental health issues can follow a stay in an intensive care unit, a condition known as PICS, for post intensive care syndrome. Rohan Mathur, a critical care expert at Johns Hopkins, says now that more attention is being … What can be done about PICS? Elizabeth Tracey reports Read More »

When someone has survived an intensive care unit stay, they may experience a host of challenges to their wellbeing known collectively as post intensive care syndrome, or PICS. Critical care expert Rohan Mathur at Johns Hopkins says sometimes the worst … How can you tell if PICS is present? Elizabeth Tracey reports Read More »

PICS stands for post intensive care syndrome, and recent data indicate that perhaps the majority of people who’ve been hospitalized in an ICU will have what are called sequelae, or lingering issues once they’re stepped down or discharged. Johns Hopkins … What kinds of issues may remain after someone has been in an intensive care unit? Elizabeth Tracey reports Read More »

Once you’ve made it through a stay in an intensive care unit, you can simply move forward in your life, right? Not exactly, as recent research indicates. So-called post intensive care syndrome, or PICS, can continue to impact the life … What is post-intensive care syndrome? Elizabeth Tracey reports Read More »

Maybe you’ve heard of CAR-T cells, a type of cell you have in your body that is supercharged in a lab and put back in to fight things like cancer. Biomedical engineering expert Jordan Green at Johns Hopkins and colleagues … There’s a new technique that may revolutionize one type of T cell therapy, Elizabeth Tracey reports Read More »

CAR-T cells are a type of immune cell that have proven very effective for treating some types of cancer, yet limitations to their use exist. Biomedical engineering expert Jordan Green at Johns Hopkins says limitations including lengthy time and expense … Can an injectable particle help supercharge your T cells? Elizabeth Tracey reports Read More »

Using polyester to wrap mRNA to create an injectable particle may soon enable targeting of your T cells to fight some cancers and autoimmune diseases.  That’s according to research by Jordan Green, a biomedical engineering expert at Johns Hopkins, and colleagues. … Can an mRNA containing particle help direct your T cells to specific targets? Elizabeth Tracey reports Read More »

Let’s say I take one type of immune cell from your blood, grow it in a lab and use a virus to cause changes in that cell so it recognizes cancer. Then I put it back in your body to … Temporary changes to T cells may empower new treatments for cancer and autoimmune disease, Elizabeth Tracey reports Read More »

Put together a shelf-stable particle with a polyester shell, a homing mechanism, and mRNA instructions, and what do you have? A new technology that may be able to train your own T cells inside your body to combat some types … Messenger RNA can be used to stimulate T cells to fight cancer and autoimmune disease, Elizabeth Tracey reports Read More »

With several studies saying oxygen measurements are too low and one saying they’re too high, how much can pulse oximeters be trusted in those with darker skin? Rohan Mathur, a critical care medicine expert at Johns Hopkins, says that oft … Trust but verify may be needed for pulse oximeters, Elizabeth Tracey reports Read More »

Critical care medicine relies on pulse oximeters, which estimate oxygen levels in someone’s blood, for many decisions regarding their care. Studies during the pandemic suggested the devices said there was more oxygen in the blood of someone with darker skin … How do we account for opposite results from studies on pulse oximeters? Elizabeth Tracey reports Read More »

Do devices that measure oxygen levels in blood, known as pulse oximeters, measure too high or too low in those with darker skin? That’s the question now that results of an FDA funded study seem to contradict those of previous … What does a recent FDA funded study on pulse oximeters show? Elizabeth Tracey reports Read More »

If you are a person with darker skin should you be worried about the levels of oxygen in your blood a pulse oximeter is giving? Critical care expert Rohan Mathur at Johns Hopkins says past studies looking at this issue … Data from pulse oximeters can really impact patient care, Elizabeth Tracey reports Read More »

Do the devices known as pulse oximeters, which measure the amount of oxygen in someone’s blood, underestimate or overestimate this value in people with darker skin? Controversy swirls with release of data from an FDA funded study that runs counter … What is up with pulse oximeters? Elizabeth Tracey reports Read More »

In the last episode of our Nursing Grand Rounds series, ‘Bringing Inquiry to the Bedside,’ Stephanie Al-Adhami and Deborah Tildsley present their research project ‘Impact of Gaming on Critical Thinking and Assessment Skills Among New-to-Practice Nurses.’ Their research project examined the impact … Episode 78: Nursing Grand Rounds – Impact of Gaming on Critical Thinking and Assessment Skills Among...