Johns Hopkins Medicine

For the first time CAR-T cells, a highly activated type of immune cell, have been used with some success to treat stomach cancer, a so-called solid tumor. William Nelson, director of the Kimmel Cancer Center at Johns Hopkins, says solid … Why has it been so hard to use CAR-T cells to treat solid tumors? Elizabeth Tracey reports Read More »

You’ve probably heard of CAR-T cells, a type of immune cells taken from someone’s body, grown up in a lab and trained to attack their cancer. CAR-Ts are known to be good for treating blood cancers like leukemia, and for … Will solid tumors now be treated with CAR-T cells? Elizabeth Tracey reports Read More »

When it comes to managing with the dog days of summer, air conditioning is very helpful, especially for people with chronic lung problems. Johns Hopkins lung health expert William Checkley says clean systems with filters that are regularly changed are … Humidity may be as important as temperature when it comes to air conditioning, Elizabeth Tracey reports Read More »

People with lung conditions like asthma or chronic obstructive pulmonary disease, abbreviated COPD, rely on air conditioning in the summer to help keep their symptoms from getting much worse. William Checkley, a lung health expert at Johns Hopkins, says it’s … If you don’t use AC properly you may make lung problems worse, Elizabeth Tracey reports Read More »

If you have any respiratory issues you likely benefit from air conditioning when the weather is hot. Lung health expert William Checkley at Johns Hopkins says you must be aware of the system’s maintenance requirements to reap its benefits. Checkley: … Proper AC maintenance is key to healthful use, Elizabeth Tracey reports Read More »

For many people air conditioning is important for alleviating symptoms of chronic respiratory disease, but Johns Hopkins lung health expert William Checkley says it’s still necessary to be aware of how AC can impact on the function of your respiratory … Sometimes air conditioning can compromise your respiratory health, Elizabeth Tracey reports Read More »

As the northern hemisphere enters full summer, many people shut their windows and turn on the air conditioning, or AC. William Checkley, a lung health expert at Johns Hopkins, says as with many things in life, it’s important to have … While AC is great at making us feel comfortable it’s also important for health, Elizabeth Tracey reports Read More »

In part 4, the focus is on Appendix C, or the Searching and Screening Tool. Appendix C helps guide the EBP team through the steps of searching for evidence that will answer their EBP question. Kim Bissett, EBP Coordinator for … Episode 66: Appendix C – 5th Edition (part 4) | Johns Hopkins Center for Nursing Inquiry Read More »

We’re taking a (temporary) break from our series on JHEBP tools to cover a new topic: abstract writing! Heather Watson, Nurse Scientist for the Johns Hopkins Health System, and Marlena Fisher, Nurse Inquiry Coordinator at the Johns Hopkins Center for … Episode 65: Tips for Writing a Solid Abstract | Johns Hopkins Center for Nursing Inquiry Read More »

Mismatch repair is just what it sounds like: when a cell divides and makes new DNA strands when a mistake is made it repairs them. Some types of cancers with a mismatch repair mutation may now be treated with an … Different types of tumors with a specific mutation may not need surgery, Elizabeth Tracey reports Read More »

Genetic analysis of most cancers is becoming more commonplace, and now identification of one specific mutation called a mismatch repair may allow people to avoid surgery entirely. Johns Hopkins Kimmel Cancer Center director William Nelson explains. Nelson: What they started … Are there cancers where surgery may be entirely avoided? Elizabeth Tracey reports Read More »

More types of gut bacteria, or greater diversity, the healthier your microbiome. That’s one message of a recent review looking at the impact of microbiome health on cancer. Kimmel Cancer Center director William Nelson at Johns Hopkins explains how gut … Which types of cancer treatment are impacted by the gut microbiome? Elizabeth Tracey reports Read More »

A recent review in the Journal of the American Medical Association asserts that the diversity of bacteria in your colon impact on the likelihood that you’ll develop cancer as well as how you may respond to treatment. William Nelson, director … If your gut microbiome isn’t healthy, is there anything that can be done about it? Elizabeth Tracey reports Read More »

The wealth of bacteria resident on and in your body may have much to do with your overall health, including how you respond to different therapies for cancer. Johns Hopkins Kimmel Cancer Center director William Nelson explains views from a … Your gut microbiome may have much to do with how you respond to cancer therapy, Elizabeth Tracey reports Read More »

Colorectal cancer screening, and rise in younger people, microplastics and cancer, immune checkpoint inhibitors and longterm toxicity, AI contributions to precision oncology and flattening of breast cancer survival rates.

Breathlessness clinic is a new approach at Johns Hopkins to assist people with chronic lung diseases to live their best lives with these often debilitating conditions. Anna Gersten, a lung expert and director of the clinic, explains who would benefit. … Who is suitable for a breathlessness clinic visit? Elizabeth Tracey reports Read More »

Being short of breath is a terrible feeling, most people agree, and it’s a feature of many lung diseases, especially as they progress. Lung expert Anna Gersten at Johns Hopkins describes how a breathlessness clinic came to be at Hopkins … What is a breathlessness clinic? Elizabeth Tracey reports Read More »

High blood biomarkers for Alzheimer’s disease found by the newly FDA approved blood test indicate the presence of two proteins in the brain called amyloid and tau. Abhay Moghakar, a neurologist and blood biomarkers expert at Johns Hopkins, says some … What are current studies doing when high levels of blood biomarkers for Alzheimer’s are found? Elizabeth Tracey reports Read More »

Let’s say you’ve taken the newly approved blood test for Alzheimer’s disease and the results indicate the presence of tau and amyloid in your brain, so you’re at risk.  Abhay Moghakar, a neurologist and blood biomarkers expert at Johns Hopkins, says … What are your options if a new blood test says you are at risk for Alzheimer’s disease? Elizabeth Tracey reports Read More »

You may have heard of a new blood test for Alzheimer’s disease just approved by the FDA. Abhay Moghakar, a neurologist and blood biomarkers expert at Johns Hopkins, says even if you are older and have symptoms of the disease, … People who develop dementia as they age most often have a mixed type, Elizabeth Tracey reports Read More »

A new blood test for Alzheimer’s disease isn’t a stand alone diagnostic tool. That’s according to Abhay Moghekar, a blood biomarkers expert and a neurologist at Johns Hopkins. Moghekar: You would still need the clinical input in the context of … A truly comprehensive test for Alzheimer’s disease may be on the horizon, Elizabeth Tracey reports Read More »

Will an FDA cleared blood test for Alzheimer’s disease ease or complicate diagnosis? Clearly in approving the test the FDA hopes for the former, yet the complete picture is more complex than that, says Abhay Moghekar, a blood biomarkers expert … Biomarkers alone don’t mean Alzheimer’s disease is present, Elizabeth Tracey reports Read More »

Positive results on the newly FDA cleared blood test for Alzheimer’s disease don’t necessarily mean you have the disease. That’s according to blood biomarkers expert Abhay Moghekar, a neurologist at Johns Hopkins. Moghekar: Whether that's the cause of your cognitive … If you get a positive result on the new blood test for Alzheimer’s disease, what does that mean? Elizabeth Tracey reports Read More...

The FDA has just cleared a blood test to help make the diagnosis of Alzheimer’s disease, which otherwise may require some fairly invasive methods. Blood biomarkers expert Abhay Moghekar, a neurologist at Johns Hopkins, says the test looks for the … Who is a candidate for the new blood test for Alzheimer’s disease? Elizabeth Tracey reports Read More »

A blood test to screen for proteins related to Alzheimer’s disease has been cleared by the FDA, and it’s designed for people who are older than 55 years of age and have cognitive symptoms. Johns Hopkins neurologist Abhay Moghekar, a … What’s the basis of the new blood test to screen for Alzheimer’s disease? Elizabeth Tracey reports Read More »