Jayde Wellnest Podcast: The Gut-Brain Reset with Juvelyne, NP

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Mission Control: The Gut and Your Health Is an overview of how the gastrointestinal system plays a central role in overall health. It explains that the gut is not just responsible for digestion, but also influences immunity, metabolism, and even mental health through the gut-brain axis. The content highlights the importance of the gut microbiome—trillions of bacteria that help regulate inflammatio...

This episode brings everything together into the  Gut Brain Reset Method : Reduce, Repair, Regulate  Why “detox” is not the goal—and what actually works long-term  The reality of living in a high-exposure world (and why perfection is not required) Step 1: Reduce Identifying your biggest daily exposure sources  Simple, sustainable swaps that lower your overall toxic load  Why consistency matters mo...

You can’t eliminate every exposure. But you can build a more resilient gut. Focus on fiber-rich foods to support beneficial bacteria. Increase plant diversity. Include anti-inflammatory foods. A stronger microbiome helps regulate inflammation and maintain gut barrier function. This is how you buffer environmental stress. Now—we bring everything together https://us.fullscript.com/welcome/jde-guzman...

You don’t need to eliminate plastic completely. Focus on the highest-impact changes. Avoid heating food in plastic. Use glass or stainless steel when possible. Switch from bottled water to filtered water. Reduce reliance on ultra-processed foods. And improve indoor air quality with ventilation. Small changes, consistently applied, make a difference. Next—we talk about strengthening the gut itself....

Ultra-processed foods impact the gut in multiple ways. They’re low in fiber, high in additives, and often packaged in plastic. So you’re getting a combination of microbiome disruption and environmental exposure. This creates a double hit to gut health. When you reduce ultra-processed foods, you’re not just improving nutrition—you’re also lowering microplastic exposure. Next—we shift into what you...

The biggest sources of microplastics are not always obvious. Bottled water is a major one. Food packaging—especially when combined with heat—is another. Ultra-processed foods carry higher exposure from both packaging and production. Even indoor air contains microplastic particles from dust and synthetic materials. This isn’t about eliminating everything. It’s about understanding where small change...

There is currently no proven way to detox microplastics from the body. No supplement, no cleanse, no shortcut. If you’re seeing products claiming to remove plastics—they’re not backed by evidence. What actually works is reducing exposure and supporting the body’s natural systems. Your liver, gut, and immune system already handle environmental stressors. The goal is to support them—not override the...

Your gut and brain are constantly communicating. This connection is known as the gut-brain axis. Signals travel through the nervous system, immune pathways, and microbial metabolites. When the gut is inflamed or imbalanced, those signals change. Microplastics may contribute to that disruption. Through microbiome imbalance and increased gut permeability, they can promote inflammatory signaling that...

Your gut lining is supposed to act like a filter. It allows nutrients in—and keeps harmful substances out. This barrier is held together by structures called tight junctions. Microplastics appear to interfere with this system. They can trigger inflammation and oxidative stress, weakening the integrity of the gut lining. This leads to increased intestinal permeability—commonly referred to as “leaky...

Let’s talk about your gut microbiome. This is the ecosystem of bacteria that helps regulate digestion, inflammation, and even mood. Emerging research shows that microplastics can disrupt this system. They can reduce beneficial bacteria and shift the balance toward more inflammatory species. This is what we call dysbiosis. And dysbiosis doesn’t stay in the gut. It shows up as bloating, irregular bo...

Today we’re starting with something most people don’t realize—microplastics are already inside the human body. They’ve been found in blood, stool, and even organs. Microplastics are tiny particles that come from the breakdown of everyday plastics—food containers, water bottles, packaging, and even clothing. We’re exposed through what we eat, drink, and breathe. This isn’t rare exposure. It’s const...

Ever wonder why a health issue keeps coming back, no matter how many prescriptions you try? Enter Functional Medicine . It’s an evolution in healthcare that moves away from the "one-size-fits-all" model. Instead of just asking what disease you have, functional medicine practitioners ask why you have it. By exploring how your gut health, hormones, stress levels, and genetics interact, thi...

Hello, my name is Juvelyne Yap De Guzman, and I’m a board-certified Adult-Gerontology Nurse Practitioner and Certified Functional and Nutritional Medicine Practitioner. ​I’ve spent about 30 years in healthcare, first as a registered nurse (20 years) and now as a nurse practitioner (9 years), caring for patients in primary care, internal medicine, nephrology, and mental health. Through all these ye...