American College of Cardiology

JACC Specialty Journals

Health EN ↓ 2085 episodes

In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including original clinical studies, translational investigations with clear clinical relevance, state-of-the art papers, and review articles. They are top ranked for impact factor and their manuscripts are among the most covered by media outlets, most talked about on social media, and most read online.

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Author

American College of Cardiology

Episodes

XGBoost Model with CMR Features for Prognostic Assessment in Patients With ST‑Segment Elevation Myocardial Infarction | JACC: Asia 20.10.2026 4:35

Commentary by Dr. Yoriyasu Suzuki.

Design and Rationale of GPS-CAD: Global Pretest Probability Study of Coronary Artery Disease | JACC: Asia 20.10.2026 4:16

Commentary by Dr. Junjie Yang.

Prediction of Paroxysmal Atrial Fibrillation with Incorporating Genomic Information Into AI-Based ECG Analysis | JACC: Asia 20.10.2026 3:07

Commentary by Dr. Qinkai Yu.

October 2026 Summary | JACC: CardioOncology 20.10.2026 1:50

Editor-in-Chief Dr. Bonnie Ky introduces the October 2026 issue of JACC: CardioOncology, featuring Part 1 of a special focus on immunology and cardio-oncology. This issue brings together state-of-the-art reviews, primers, original research, and clinical cases examining the immune system's central role in cancer and cardiovascular disease. Topics include the mechanisms and clinical implications of...

Fibrotic Rewiring of CD8+ T-cells by Doxorubicin Drives Pathological Remodeling of Cardiac Extracellular Matrix | JACC: CardioOncology 20.10.2026 2:36

Dr. Caitlin O'Meara discusses a JACC: CardioOncology study showing that doxorubicin reprograms CD8+ T cells into matrix-remodeling T cells (mxT-cells) that produce lysyl oxidase (LOX) and stiffen the cardiac extracellular matrix through HIF1α-P53-TGFβ signaling. She explains how this new immune mechanism of anthracycline cardiotoxicity could lead to therapies that prevent cardiac fibrosis, cardiom...

High-Sensitivity Cardiac Troponin T and I Discordance in Patients Receiving Immune Checkpoint Inhibitors | JACC: CardioOncology 20.10.2026 5:03

Dr. David Austin discusses a JACC: CardioOncology study showing that high-sensitivity cardiac troponin T was elevated in 37.9% of patients starting immune checkpoint inhibitor (ICI) therapy, compared with only 1.8% for high-sensitivity troponin I, a discordance linked to older age, male sex, and kidney dysfunction. He explains what this means for troponin assay selection, baseline testing, and ICI...

Inflammatory Cell Profiles in Early- and Late-Manifestation Immune Checkpoint Inhibitor Myocarditis | JACC: CardioOncology 20.10.2026 3:30

Dr. Cristina Gil-Cruz discusses a JACC: CardioOncology study comparing early- and late-manifestation immune checkpoint inhibitor (ICI) myocarditis, where endomyocardial biopsies showed greater T-cell and macrophage infiltration in early cases despite similar left ventricular ejection fraction and fibrosis. She explains what these inflammatory cell profiles mean for cardio-oncology care, from immun...

Impact of Device Position and Aortic Valve Prolapse on Outcomes After Transcatheter VSD Closure | JACC: Asia 07.10.2026 3:33

Commentary by Dr. Timothy Un.

Prognostic Impact of Residual Thrombus After Aspiration Thrombectomy in ST-Elevation Myocardial Infarction | JACC: Asia 07.10.2026 4:26

Commentary by Dr. Ziyad Ghazzal.

Sex-Specific Lipid, Apolipoprotein B, and Lipoprotein(a) Responses to Berberine Based on 2 Randomized Placebo-Controlled Trials | JACC: Asia 07.10.2026 3:22

Commentary by Dr. Yihang Fan.

Lifestyle and Metabolic Health, Low-Grade to Clinically Elevated Albuminuria, and Cardiovascular-Renal Diseases | JACC: Asia 07.10.2026 3:58

Commentary by Dr. Hongmei Yan.

Efficacy and Safety of Quarterly Dosing SHR-1918 in Patients With Suboptimally Controlled Hyperlipidemia | JACC: Asia 07.10.2026 4:31

Commentary by Dr. Xiaojie Xie.

Oncologic Benefits and Cardiovascular Risks of Pembrolizumab: Insights From a Nationwide Lung Adenocarcinoma Cohort | JACC: Asia 06.10.2026 4:20

Commentary by Dr. Koohyar Ahmadzadeh.

Author Interview: Cholesterol Management Gaps Among Patients with Established Coronary Artery Disease Hospitalized for Acute Coronary Events | JACC: Advances 06.10.2026 24:47

Dinesh Kalra, Todd Villines, and Lisandro Colantonio discuss the importance of this article, what encouraged Dr. Colantonio to conduct this research, and how clinicians can address the concerns patients have.

Association of Implantation Depth with Hemodynamics and Mechanical Consequences in Small Valve-in-Valve TAVR | JACC: Asia 06.10.2026 4:00

Commentary by Dr. Shinichi Shirai

Comparison of ASCVD Risk Prediction Models in STEMI: Insights from a South Asian Cohort | JACC: Asia 06.10.2026 4:01

Commentary by Dr. Justin Paul Gnanaraj

Author Interview: Defining Clinically Meaningful Within-Patient Changes in Heart Failure | JACC: Heart Failure 02.10.2026 25:48

Akshay Desai and Amin Yehya discuss the newest JACC: Heart Failure Position Statement that proposes a pragmatic framework for defining clinically meaningful within-patient changes across heart failure outcomes to improve the patient-centeredness of care during shared decision-making. Learn more about the article: https://www.jacc.org/doi/10.1016/j.jchf.2026.103310

Deep Dive Dialogue: Effect of Evolocumab on Grafts Post-Coronary Artery Bypass Surgery: Post-hoc Analysis of NEWTON-CABG CardioLink-5 | JACC: Advances 02.10.2026 23:52

Dinesh Kalra, Andrew Choi, and G. B. John Mancini discuss the author group's post hoc analysis of the randomized NEWTON-CABG CardioLink-5 trial.

Issue Summary: September 2026 | JACC: Advances 29.09.2026 9:24

Audio Summary of three articles from the September 2026 issue of JACC: Advances.

Multimodality Imaging and Pace-Mapping Patterns in Patients With Cardiac Sarcoidosis and Ongoing Inflammation Undergoing Ventricular Tachycardia Ablation | JACC: Clinical Electrophysiology 18.09.2026 5:11

In this episode, Frank Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a study of ventricular tachycardia ablation in patients with active cardiac sarcoidosis. Using integrated FDG-PET and cardiac MRI imaging, the investigators found that VT exit sites were often located in areas of active inflammation, while more proximal circuit sites were associated with scar. Pati...

Author Interview: Aortic Stenosis Mortality Across the TAVR Expansion Era, 1999-2024: Rising Mortality in Middle-Aged Adults and a Widening Rural-Urban Gap | JACC: Advances 18.09.2026 23:09

Nicole Bhave, Ashwini Kerkar, and Ahmed Kamal Siddiqi discuss what inspired this study, differences in mortality trends among age groups, and the most important takeaways from the paper.

Computed Tomography–Defined Ridges and Functional Mapping in Ablation of Postinfarction Ventricular Tachycardia | JACC: Clinical Electrophysiology 15.09.2026 4:42

In this episode, Frank Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a study evaluating how CT-defined myocardial ridges and functional mapping can be combined to identify critical ablation targets in post-infarction ventricular tachycardia. The investigators found that VT target sites frequently localized to CT-defined ridges, particularly those associated with pri...

Hemodynamic Responses to Exercise and Predictors of Exercise Capacity in Mitral Stenosis: Exercise Catheterization Study | JACC Asia 14.09.2026 0:59

Commentary by Dr. Jian'an Wang.

Effect of Colchicine on Left Atrial Mechanics in Rheumatic Heart Disease: COL-RHD A Pilot Trial | JACC Asia 14.09.2026 0:56

Commentary by Dr. Jian'an Wang.

Clopidogrel Vs Aspirin Monotherapy for Secondary Prevention After Percutaneous Coronary Intervention: A Nationwide Cohort Study | JACC Asia 14.09.2026 0:58

Commentary by Dr. Jian'an Wang.