Intelligent Medicine | The Best of High Tech Medicine and Alternative Modalities

Registered dietitian Leyla Muedin discusses a Frontiers in Microbiology paper suggesting certain probiotics may help sequester heavy metals. The study, sponsored by the Italian company Probiotical and conducted with University of Ghent and University of Piedmont Orientale, researchers used in vitro testing and the SHIME gut simulator to assess Lactiplantibacillus plantarum, Lactobacillus crispatus...

Dealing with the heat - Europeans' disdain for air conditioning I have scaly and bumpy areas on my scalp that itch! Did homeopathic human growth hormone increase my cholesterol?

Which is more effective, vitamin K2 or K4? How long can I take L-tryptophan as a sleep aid?  What about 5-HTP? Is there any remedy for frequent nighttime urination? What are some suitable supplements I can take for exercise recovery?

Immune Regulation, Omega-3 Nuance, and Himalayan Tartary Buckwheat with Dr. Austin Perlmutter, chief science officer of Big Bold Health . He details immune regulation as a nuanced, multidimensional system shaped by diet and lifestyle rather than simple “boosting.” Perlmutter explains Big Bold Health’s focus on immunometabolism, educating about immune complexity, and conducting studies on nutraceut...

Dr. Hoffman continues his conversation with Dr. Austin Perlmutter, chief science officer of Big Bold Health . 

AI and Generative Biology: Authoring Life, Redesigning Healthcare, and Building Guardrails: Physician and molecular biologist Dr. Adrian Woolfson, co-founder of Genyro , a biotechnology company specializing in synthetic genome design and construction, and author of “ On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence ,” discusses the convergence of AI with synt...

Dr. Hoffman continues his conversation with physician and molecular biologist Dr. Adrian Woolfson, co-founder of Genyro , a biotechnology company specializing in synthetic genome design and construction, and author of “ On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence .”

Europeans swelter through historic heat wave—but many resist air conditioning due to ingrained cultural attitudes; Break a sweat to beat the heat; Evidence that aged garlic extract curbs atherosclerosis risk; How to stave off age-related muscle atrophy; Probiotic-infused underwear to nourish the skin microbiome? Niacin augments glioblastoma treatment; Creatine for depression.

Melatonin can reduce chronic pain; Ultra-processed foods are becoming a worldwide scourge; Do biopsies spread cancer? Sauna benefits for staving off dementia; What may cause blood sugars to deteriorate in a heretofore well-controlled diabetic? Causes of excessive sleepiness.

Bone Health Beyond Calcium: Vitamin D, K, Protein, Medications, and Metabolic Risks: Registered dietitian nutritionist Leyla Muedin discusses factors affecting bone health, osteopenia/osteoporosis, and limitations of bone mineral density as a measure of bone strength. She emphasizes optimizing vitamin D via 25-hydroxy D testing (aiming roughly 55–85 and avoiding over 100), ensuring vitamin K for p...

Carnivore diet controversies What is a normal oxygen saturation?  Mine has been 92-93 lately?  Is that okay?

I've worked for many years on my feet and had surgery on both knees.  How much glucosamine should I take? Can you discuss oral vs. IV chelation?  How do you determine which is appropriate? How important is nitric oxide, and how can I increase mine? Are there any supplements I should stop taking before getting blood tests?

Cardiovascular Protection Beyond Statins--Nattokinase, Vitamin K2 MK-7, and Clinical Cardio Six: Neil Levin of NOW Foods/ Protocol for Life Balance details cardiovascular protection beyond cholesterol-lowering drugs, emphasizing nutrient sufficiency, therapeutic “nutraceutical” dosing, and physician partnership with testing. They discuss nattokinase from fermented natto (typical 2,000 fibrinolytic...

Dr. Hoffman continues his conversation with Neil Levin, the Senior Nutrition Education Manager and a product formulator for NOW(r) Foods and Protocol for Life Balance . 

Urolithin A (Mitopure) and Mitochondrial Renewal--Muscle, Immune, and Skin Benefits: Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline details urolithin A and Timeline’s branded supplement Mitopure. She describes urolithin A’s discovery through pomegranate research and worm studies showing a 45% lifespan increase. She discusses human research including improved walking di...

Dr. Hoffman continues his conversation with Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline . 

“The quick and the dead”: 80+ “Supermovers” show slowed cognitive decline; Dietary polyphenols help overcome vascular effects of prolonged sitting; Pros and cons of ketamine therapy for depression; Time-restricted eating alters microbiome to promote weight loss; Magnesium—what research reveals about better sleep, stress resilience, and whole-body wellness.

CBD may slow Alzheimer’s progression by tamping down brain inflammation; Fifty million dollar settlement in Gardasil Classic action; Urethral stricture as a side effect of ablation for enlarged prostate; Zero-sugar diet may have unanticipated adverse health consequences; Are there drug-free alternatives for atrial fibrillation? Can you reverse lactose intolerance with a skin patch?

Vitamin K2 (MK-7) and Coronary Artery Calcification: Insights from a 2-Year Trial: Nutritionist Leyla Muedin discusses a two-year randomized clinical trial in JAMA Cardiology from Maastricht University Medical Center reporting that daily vitamin K2 (menaquinone-7, MK-7) at 360 mcg slowed progression of coronary artery calcification (CAC) in 180 patients with confirmed atherosclerotic cardiovascula...

World Cup! What did humans eat from the Ice Age to the Bronze Age? What supplements should I avoid while undergoing radiation therapy for prostate cancer? What is the treatment for sarcoidosis of the lung? Both my friend and his wife have it.

I'm 78 and had a hysterectomy.  Is it safe for me to eat tofu or other soy foods? Mitopure joins L'Oreal to create a face cream with Urolithin A. Does taking hyaluronic acid orally cause water retention? Can you discuss ETA contained in New Zealand green mussels? What are your thoughts on using vibration devices to help osteoporosis?

Nathan Jones, founder and CEO of Xlear, Inc. , reveals xylitol’s role in supporting oral and nasal “gateway” microbiomes by selectively starving acid-producing Strep mutans rather than indiscriminately killing bacteria, and warns that harsh mouthwashes can disrupt beneficial oral bacteria linked to nitric oxide production and possibly blood pressure. Jones outlines Spry and Xlear products (gum, mi...

Dr. Hoffman continues his conversation with Nathan Jones, founder and CEO of Xlear, Inc.

Nitric Oxide Explained: Vascular Health, Exercise Performance, and N1o1 with Dr. Nathan Bryan , international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. He details NO as a ubiquitous messenger affecting blood flow, erectile function, cognition, exercise performance, endothelial dysfunction, and agin...

Dr. Hoffman continues his conversation with Dr. Nathan Bryan , international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health.