Tyler Vaglivelo

In the Pipeline

Health EN ↓ 7 episodes

This is a podcast about advancements in clinical trials as they emerge, before regulatory milestones or publication of associated data. The views expressed are my own, and I have no financial affiliations with the companies discussed, nor is this affiliated with any employer.

Author

Tyler Vaglivelo

Episodes

Updates ON RAS with Daraxonrasib (3/23/26 - 4/13/26) 14.04.2026 18:28

If you have any questions, please reach out at inthepipelinepodcast@gmail.com or on Twitter/X @tdonatellov. Thank you for listening! Sources: Daraxonrasib Demonstrates Unprecedented Overall Survival Benefit in Pivotal Phase 3 RASolute 302 Clinical Trial in Patients with Metastatic Pancreatic Cancer IDEAYA Biosciences and Servier Announce Positive Topline Results from Phase 2/3 Registrational Trial...

Varset-for-a Masked Approach (3/1/26-3/22/26) 24.03.2026 20:42

If you have any questions, please reach out at inthepipelinepodcast@gmail.com or on Twitter/X @tdonatellov. Thank you for listening! Topics: CytomX’s Varsetatug Masetecan (EpCAM PROBODY® ADC) Continues to Demonstrate Positive Data Supporting Potential as a New Treatment Option in Late-Line Colorectal Cancer Bristol Myers Squibb Announces Positive Phase 3 Results from the SUCCESSOR-2 Study of Oral...

Important lidERAbilities (11/30/25-1/4/26) 06.01.2026 16:41

If you have any questions, please reach out at inthepipelinepodcast@gmail.com or on Twitter/X @tdonatellov. Thank you for listening! Topics: Ph III (lidERA) giredestrant in adjuvant ER+/HER2-negative, early BC TERN-701 CARDINAL Trial December 2025 Data Update JANX007 Phase 1 Clinical Update

Time to be bASHful (11/16-11/29) 02.12.2025 13:06

If you have any questions, please reach out at inthepipelinepodcast@gmail.com. Thank you for listening! Topics: Sonrotoclax (BGB-11417) monotherapy in patients with Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL) previously treated with a bruton tyrosine kinase (BTK) inhibitor: Early results from A phase 1/2 study Primary results from VAYHIT2, a randomized, double-blind, phase 3 trial of iana...

Best in BezuCLAStinib (11/2-11/15) 21.11.2025 12:49

If you have any questions, please reach out at inthepipelinepodcast@gmail.com. Thank you for listening! Topics: Cogent Biosciences Reports Positive Results from Bezuclastinib PEAK Phase 3 Trial in Gastrointestinal Stromal Tumors (GIST) Detalimogene Demonstrates Improved Complete Response Rate of 62% at 6 Months Relmada Announces FDA Feedback Supporting 2 Separate Acceptable Registrational Study Pa...

Epigenetic Bonanza (10/19-11/1) 05.11.2025 9:43

The first episode of the relaunched podcast, focusing exclusively on oncology/hematology. If you have any questions, please reach out at inthepipelinepodcast@gmail.com. Thank you for listening! Topics: Tango Therapeutics Reports Positive Data from Ongoing Phase 1/2 Study with Vopimetostat (TNG462) in Patients with MTAP-deleted Cancers Halda Therapeutics Announces First-in-Human Results for HLD-091...

Episode 1 - July 2025 10.08.2025 27:41

Thank you for checking out the first episode of the podcast! If you have any questions or corrections you would like for me to address you can reach me in the following ways: Email: inthepipelinepodcast@gmail.com Twitter/X: tdonatellov