In the Know with Amol Sarva

🎙️ Episode Guide — PJ Parson (Northzone) Welcome to my series on OG NY Tech Celebrating 30 years of the New York tech ecosystem, from 1995 to now. PJ Parson is a partner at Northzone, best known for backing Spotify when it expanded to New York in 2012. But his path to venture capital wasn’t linear—it ran through small-town Sweden, jazz musicianship, tour guiding in Italy, ski resorts in France, Mc...

>updated with vibier sound!< Welcome to my series on OG NY Tech Celebrating 30 years of the New York tech ecosystem, from 1995 to now. Kevin Ryan joined DoubleClick in 1996, just months after it was founded—and helped turn it into the most important New York technology company of the internet era. From there, he went on to co-found or incubate a generation of defining NYC companies: MongoDB , B...

Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now. Howard Morgan started as an engineer and professor in the early computing days, and ended up building three (four? five?) huge and import investment groups. Renaissance... Idealab... and listen for more on the early computing gods through to Bitcoin and AI. 🎙️ Episode Chapters — Howard Morgan Compute...

>updated with vibier sound!< Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now. Fred Wilson's USV is kind of a 'nuff said, to borrow NYC comic book language. Hear the very early days and listen past through into the epilogue to hear Fred on music scenes and the process of discovery. 🎙️ Episode Chapters SECTION I — The Core Interview: Building New...

Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now. Alan Patricof's been at it since he graduated from Columbia Business School just a couple years apart from Warren Buffett. And you might as well think of him in that same legend league, in Alan's case for Venture Capital. We start from the very early days and go right through today. 🎙️ Episode Chapte...

Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now. Ben Lerer tells us what ideas led to the creation of a whole new type of media company in the 2000s -- Thrillist -- and the age of newsletters and bloggers in New York, and how the powerhouse seed-stage venture firm Lerer Hippeau came from it all.

Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now. Dennis Crowley tells us how he got to New York and the early internet culture in the media/Wall Street world: and how it all led to Foursquare -- the art of the game 🎙️ Episode Chapters — Dennis Crowley From Punk Zines to Foursquare: How New York Taught the Internet to Find Itself SECTION I — The Cor...

Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now. Albert Wenger tells me about his 20 years at USV, and how NY went from apps-mostly to deep and infra. 🎙️ In the Know — OG NY Tech Guest: Albert Wenger (Union Square Ventures) Theme: 30 years of New York tech — personal origin story, early ecosystem formation, iconic USV bets, and future-facing framew...

Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now. Owen Davis tells us how advertising powered early NYC tech and the big transition post-dot-com-crash to both consumer and enterprise tech superstars from New York.

Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now. John Borthwick tells us the roots story of media and art and agencies at the heart of the early NY tech ecosystem and some of the players, and takes it through predictions for what to expect today.

Pablos built one of the first decentralized money networks, the first experimental Blue Origin rockets, one of the first handheld computers, invented 1000s of new patents with Nathan Myhrvold, and most recently launched a deeptech venture firm called Deep Future. And now, on July 12, expect his book: "Deep Future". -- Pablos Holman and Amol on Deep Future Amol Sarva: [00:00:00] On today's episode,...

So you missed the all-day all-science+technology collection of superstars gathered by LifeX and Bits in Bio at Fenwick in New York? Wondering what the frontiers of foundation models in bio, longevity, startups and more are pushing? Now you can use the cheat code and just listen to this synopsis of the big highlights and discussion points.

Jim, founder of Juvenescence, old China and Russia hand, and investor in our fund LifeX sends me an email every morning with lots of attachments that he read that morning. Here's what he's been thinking about the last month.

Read the post here: https://amol.sarva.co/%f0%9f%90%8c-kohei-saitos-slow-down-de-acc-manifesto/

I gave a talk in Stockholm last year, that I asked these robots to discuss. Hope you enjoy it. This doesn't look LIKE me but it does sort of resemble what I could possibly look like. It was the first draft. Some better prompting got us to the final image.

The legendary tech beat reporter is back with a team effort newsletter covering some of the most interesting people in tech. Listen in to hear what he's been thinking about over the last 10 issues.

We analyzed the 1,000s of companies we're watching and investing in at LifeX. We looked at every update email from every CEO and every conversation notes from every team member. And we made hits outlook for the year ahead, automagically. (Excuse robo-typos.) Enjoy!

We synthesized the dozens of outlook reports from Wall Street analysts on health, biopharma, and related trends. Listen in to Amolbot (an automated Amol) and co-hosts.

We synthesized the dozens of outlook reports from Silicon Valley observers of techbio for AI x Health startups and trends. Listen in to Amolbot (an automated Amol) and co-hosts.

Dr. B is an expert on gut health and shouting its power from the rooftops, both in his practice and writings but also through the company Zoe where he is US medical director. Some interesting news about coffee in this one. Metabolic Health is the biggest medical breakthrough of the moment. Dive in!

The journey from food through digestion to your liver to energy stores and metabolizing work is the obsession of sports science - and hugely relevant to metabolic health overall. Let's get this perspective from research professor Derek Huffman at Einstein Medicine in New York. Dive into metabolic health!

The different foods we eat and how they interact make a huge difference in disease progression, weight, and everything else. Dr. Jeff Alfonsi is a practicing physician for years, and chief medical officer of RxFoods which is designed to identify what you are eating and how to get better results. Metabolic Health is the biggest medical breakthrough of the moment. Dive in.

Let's understand an overlooked dimension of the weight loss revolution underway -- the microbes in the digestive system themselves, potentially where GLP-1s come from in the first place. Duke's gut biome expert Maya Kaelberer gives us a guide. Metabolic Health is the biggest medical breakthrough of the moment. Dive in!

Metabolic Health is the biggest medical breakthrough of the moment Let's understand the cellular mechanisms and some of the most promising and widely used drugs in the world with one of the foremost researchers in the field, Matt Kaeberlein, formerly of University of Washington and now founder of longevity company Optispan

Metabolic Health is the biggest medical breakthrough of the moment Mapping all the ways the GLP-1 drugs like Ozempic do and might work means we need to understand the biome and the efficacy of surgical interventions. We talk to Professor Randy Seeley who directs University of Michigan's Nutrition Obesity Research Center