Jack McDonnell

Immune Matters: a PIDTC Podcast

Health EN ↓ 6 episodes

Join Jack McDonnell, MD , a pediatric immunologist and assistant professor at Cleveland Clinic Lerner College of Medicine , and Elie Haddad, MD, PhD , a clinician-researcher in pediatric immunology, full professor at the University of Montreal , and head of the Immunology and Rheumatology department at CHU Sainte-Justine , as they explore the evolving world of immune deficiency and dysregulation . Presented by the Primary Immune Deficiency Treatment Consortium (PIDTC) , this podcast features conversations with leading experts, pioneering researchers, patients, and advocacy groups . Each episo...

Author

Jack McDonnell

Episodes

PIDTC Immune Matters - Episode 6 Patient Perspective BMT Survivor 04.05.2026 34:43

In this episode of Immune Matters, hosts Jack McDonnell and Elie Haddad speak with Dr. Simon Tabchi, a physician, transplant survivor, and advocate living with a history of Wiskott-Aldrich syndrome (WAS). Simon shares his childhood diagnosis, bone marrow transplant journey, and how surviving a rare primary immunodeficiency inspired his career in medicine and patient advocacy. The discussion explor...

PIDTC Immune Matters - Episode 5 Emapalumab 19.03.2026 31:13

In this episode of Immune Matters, hosts Jack McDonnell and Elie Haddad speak with Dr. Joseph Oved, a pediatric hematologist-oncologist and transplant specialist at Columbia University, about the biologic therapy emapalumab (Gamifant). The discussion explores how this anti–interferon-gamma monoclonal antibody is used to treat hyperinflammatory conditions such as primary hemophagocytic lymphohistio...

Immune Matters Episode 4, Rebecca and Dani, Chiron 06.12.2025 30:06

In this episode of Immune Matters, hosts Jack and Elie discuss the Chiron platform with guests Dr. Rebecca Marsh and Dr. Dani Arnold. Chiron is a data interaction tool designed by the PIDTC for researchers in the field of immune deficiency. Dr. Marsh and Dr. Arnold explore Chiron's features and clinical applications, emphasizing its potential to enhance patient care and research outcomes. The conv...

Immune Matters Episode 3, Jen, SCID 26.08.2025 37:10

In this episode of Immune Matters, Dr. Jack McDonnell and Dr. Elie Haddad welcome Dr. Jen Heimall, an expert in severe combined immune deficiency (SCID). They discuss the complexities of SCID, including its diagnosis, management, and the importance of newborn screening. Dr. Heimall shares insights from her research on treatment outcomes and the significance of collaboration in SCID care. The conve...

Immune Matters Episode 2, Jen, Chronic Granulomatous Disease 14.06.2025 34:48

In this episode, Dr. Jennifer Leiding, a pediatric clinical immunologist, discusses Chronic Granulomatous Disease (CGD) with Jack and Elie. CGD is an inherited immune deficiency that leads to severe infections and autoimmunity. She explains the dual nature of immune deficiency and autoimmunity in CGD patients, the role of transplantation as a treatment option, and the expectations for families rec...

Immune Matters Episode 1, Blachy and Jessie, Wiskott Aldrich 31.05.2025 35:32

In this episode of Immune Matters: a PIDTC Podcast, Dr. Jack McDonnell and Dr. Elie Haddad, along with guests Dr. Blachy Davila and Dr. Jessie Alexander, delve into Wiskott-Aldrich syndrome, a rare X-linked immunodeficiency affecting boys. They discuss the clinical manifestations, management strategies, and the importance of bone marrow transplantation as a definitive treatment. The conversation h...