ICU Ed and Todd-Cast

Send us a Text Message (please include your email so we can respond!) Episode 21! In this episode we talk about "Extracorporeal Life Support in Infarct-Related Cardiogenic Shock" published August 2023 by Thiele et al in NEJM. Then we dive into our neglected mail bad to try to answer some listener questions. ECLS-SHOCK: https://pubmed.ncbi.nlm.nih.gov/37634145/ If you enjoy the show be su...

Send us a Text Message (please include your email so we can respond!) Episode 20! In this episode we talk about "Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation" published October 2022 by the ANZICS group in JAMA. We have the first author and senior authors on the accompanying systematic review a...

Send us a Text Message (please include your email so we can respond!) Episode 19! In this episode we talk about "Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation" published November 2022 by Semler et al in the New England Journal of Medicine. We have the first author, Matt Semler, on with us to talk to us about the trial and his improv comedy claim to...

Send us a Text Message (please include your email so we can respond!) Episode 18! In this episode we talk about "Early adjunctive methylene blue in patients with septic shock: a randomized controlled trial" published March 2023 by Ibarra-Estrada et al in Critical Care. We made a planning mistake so no old article today so we left it short! Methylene blue: https://pubmed.ncbi.nlm.nih.gov/...

Send us a Text Message (please include your email so we can respond!) Episode 17! In this episode we talk about "Aggressive of Moderate Fluid Resuscitation in Acute Pancreatitis" published September 2022 by de-Madaria et al in the New England Journal of Medicine and then talk about the landmark study "Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock&quo...

Send us a Text Message (please include your email so we can respond!) Episode 16! In this episode we talk about "Phenobarbital-Based Protocol for Alcohol Withdrawal Syndrome in a Medical ICU: Pre-Post Implementation Study" published April 2023 by Alwakeel et al and then talk about the landmark study TRICC or "A multicenter, randomized, controlled clinical trial of transfusion requir...

Send us a Text Message (please include your email so we can respond!) Episode 15! In this episode we talk about "Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest" published October 2022 by Kjaergaard (apologies in advance for the pronounciation...) et al and then talk about the prospective observational cohort "Weaning from mechanical ventilation in intensive care unit...

Send us a Text Message (please include your email so we can respond!) Summer is here and we're getting a chance to catch our breath! Unless there is a surprise article drop we anticipate that our next few episodes are going to be a little bit different as we catch up on non-RCT happenings in the critical care world. This episode is the same, our discussion on ARDS is a fascinating history les...

Send us a Text Message (please include your email so we can respond!) Episode 13! We made it this far! Instead of keying in on one major article from the Critical Care Reviews Conference 2023 we decided to do a pot pourri of the entire conference. It was quite the whirlwind, if there is any point or trial you want us to elaborate please contact us and let us know! Otherwise we discuss EXIT-SEP in...

Send us a Text Message (please include your email so we can respond!) This is a little off schedule (and a little long!) but we were SO EXCITED to have the opportunity to sit down and talk with Matt Prekker, the lead author on the DEVICE trial evaluating video versus direct laryngoscopy for tracheal intubation which was published TODAY, June 2023, in the New England Journal of Medicine and present...

Send us a Text Message (please include your email so we can respond!) Episode 11/12 (depending on how you count the ATS episode)! This time we discuss "Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia" published in NEJM May 2023. Apologies for the lack of old articles, with summer travel plans we've prepped for a couple but ran out of recording time. When...

Send us a Text Message (please include your email so we can respond!) ATS 2023! Unfortunately for us, there were more breaking pulmonary articles compared to critical care but we did get this great article by the late Dr. Curtis published in JAMA during the conference "Intervention to Promote Communication About Goals of Care for Hospitalized Patients With Serious Illness".  Article: htt...

Send us a Text Message (please include your email so we can respond!) Episode 10! In this episode we rambled a little bit and limited ourselves to just our new article which was "Haloperidol for the Treatment of Delirium in ICU Patients" published by Andersen-Ranberg et al in NEJM 2022. Of note, we go back and forth a little bit between "haloperidol" and the brand name "Ha...

Send us a Text Message (please include your email so we can respond!) Episode 9! In this episode we step a little out of our comfort zone to talk about a couple of analyses which caught our interest recently:  1) "Comparative Effectiveness of Fludrocortisone and Hydrocortisone vs Hydrocortisone Alone Among Patients With Septic Shock" published  by Bosch et al March 2023 in JAMA Internal...

Send us a Text Message (please include your email so we can respond!) Episode 8! In this episode we discuss NUTRIREA 3 or  "Low versus standard calorie and protein feeding in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group trial" by Reigner et al published Lancet Respiratory Medicine 2023.  The "old" article is NUTRIREA 1 or &quot...

Send us a Text Message (please include your email so we can respond!) Episode 7! In this episode we discuss CAPECOD or  "Hydrocortisone in Severe Community-Acquired Pneumonia" by Dequin et al published NEJM 2023. No second article because this was an important trial which has a lot of messy history that we review, including the ESCAPe trial published last year, before we start our discus...

Send us a Text Message (please include your email so we can respond!) Episode 6! In this episode we discuss 1) "Treating Rhythmic and Periodic EEG Patterns in Comatose Survivors of Cardiac Arrest" by Ruijter et al published NEJM 2022 and 2) "Dexamethasone treatment for the acute respiratory distress synrome" by Villar et al published Lancet Respiratory Medicine 2020.  This epis...

Send us a Text Message (please include your email so we can respond!) Episode 5! In this episode we again go to a new and old article 1) "Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-piece" by Thille et al published NEJM 2022 and 2) "Intravascular Complications of Central Venous Catheterization by Insertion Site" or "3SITES" by Parienti et al...

Send us a Text Message (please include your email so we can respond!) EPISODE 4! In this episode we are SUPER excited to welcome friend of the podcast Whitney Gannon who is our local ECMO expert to talk about the inspiration for her research in ECMO (ECMO liberation and anticoagulation practices in ECMO) AND the INCEPTION trial, or the Early Extracorporeal CPR for Refractory Out-of-Hospital Cardia...

Send us a Text Message (please include your email so we can respond!) BONUS Episode Time! Right after we started the podcast where one of the episodes was the TEAM trial for early mobilization, SCCM happened and there was yet another early mobilization trial. Since we just had an early mobility discussion we decided to drop our thoughts on this, how it relates to TEAM, and a related meta-analysis...

Send us a Text Message (please include your email so we can respond!) Episode 3! In this episode switch it up and review 2 NEW articles that published with SCCM 2023 1)"Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension" or CLOVERS by the PETAL Network published NEJM 2023 and 2) "Effect of Non-Invasive Ventilation After Extubation in Critically Ill Patients...

Send us a Text Message (please include your email so we can respond!) Episode 1! In this episode we talk about what we're all about and dive right into our first two articles 1)"Defibrillation Strategies for Refractory Ventricular Fibrillation" by Cheskes et al published NEJM 2022 and 2) Comparison of Dopamine and Norepinephrine in the Treatment of Shock by De Backer et al published...

Send us a Text Message (please include your email so we can respond!) Episode 2! In this episode we again go to a new and old article 1)"Early Active Mobilization during Mechanical Ventilation in the ICU" by the ANZICS group published NEJM 2022 and 2) "Albumin Replacement in Patients with Severe Sepsis or Septic Shock" by Caironi et al published NEJM 2014.  If you enjoy the sho...