ICU Ed and Todd-Cast

Send us a Text Message (please include your email so we can respond!) Episode 95! In this episode we talk about "Sodium Bicarbonate for In-Hospital Cardiac Arrest" by Granfeldt et al and "Sodium Bicarbonate for Critically Ill Adults with Metabolic Acidosis and Shock" published by the ANZICS group both presented at the CCR26 conference. BiHCA: https://pubmed.ncbi.nlm.nih.gov/422...

Send us a Text Message (please include your email so we can respond!) Episode 94! In this episode we give some general reactions to the CCR conference, discuss our impact on the critical care world, and talk briefly about 3 of the presentations from the conference that did NOT have a simultaneous publication (REMAP-CAP oseltamivir, FISSH, and SAVE-ICU) If you enjoy the show be sure to like and sub...

Send us a Text Message (please include your email so we can respond!) Episode 93! In this episode we go over TOWAR or "Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage" by Sperry et all published in NEJM and "Remote Multicomponent Rehabilitation in Intensive Care Unit Survivors" published by O'Neill et al in JAMA both in May 2026 and presented at...

Send us a Text Message (please include your email so we can respond!) Episode 92! In this episode we talk about "Restrictive vs Liberal Physical Restraint Strategies in Critically Ill Patients" published in JAMA by Sonneville et al April 2026! R2D2 (pubmed): https://pubmed.ncbi.nlm.nih.gov/41841304/ R2D2 (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2846726 If you enjoy...

Send us a Text Message (please include your email so we can respond!) Episode 91! In this episode we talk about "Dexmedetomidine for treatment of hyperactive delirium in non-intubated ICU patients" published by Godet et al in Intensive Care Medicine October of 2025! We are going to be on a one article per episode kick for a while but hope to get back to normal programming soon! 4D: https...

Send us a Text Message (please include your email so we can respond!) Episode 90! In this episode we talk about the 2026 Surviving Sepsis Campaign Guidelines lead by Prescott et all and published in Critical Care Medicine in March of 2026! We review all that's new and all that's changed If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on...

Send us a Text Message (please include your email so we can respond!) Episode 89! In this episode we talk about HI-PEITHO or catheter directed thrombolysis versus conventional anticoagulation for intermediate risk pulmonary embolism. This was published in the New England Journal of Medicine by Rosenfield et al. HI-PEITHO: http://nejm.org/doi/full/10.1056/NEJMoa2516567 HI-PEITHO (pubmed): https://p...

Send us a Text Message (please include your email so we can respond!) Episodes 88! In this episode we talk about guidelines recently released for the management of pulmonary embolism and cardiac arrest! A little hap hazard of an episode as we jump around from topic to topic but good to highlight things that are new and things that are changing! PE: https://pubmed.ncbi.nlm.nih.gov/41712898/ CPR: ht...

Send us a Text Message (please include your email so we can respond!) Episode 87! In this episode we talk about Albumin with two related studies, ALBIOS ("Albumin replacement in patients with severe sepsis or septic shock" by Caironi et al) and ARISS ("Albumin Replacement Therapy in Septic Shock" by Sakr et al) ALBIOS: https://pubmed.ncbi.nlm.nih.gov/24635772/ ARISS: https://pu...

Send us a Text Message (please include your email so we can respond!) Episode 86! In this episode we talk about endotracheal tubes or "Hospital and long-term outcomes for subglottic suction and polyurethane cuff versus standard endotracheal tubes in emergency intubation" published in Lancet Respiratory Medicine February 2026 by Treggiari et al. Pubmed: https://pubmed.ncbi.nlm.nih.gov/413...

Send us a Text Message (please include your email so we can respond!) Episode 85! In this episode we go over LIBERATE-D or "A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury" by Liu et al in JAMA 2026. We have the second author, Eddie Siew, on with us to discuss! LIBERATE-D (pubmed): https://pubmed.ncbi.nlm.nih.gov/41201895/ LIBERATE-...

Send us a Text Message (please include your email so we can respond!) Episode 84! In this episode we finish up our discussion of the articles presented with the CCR Down Under Conference with ACTiVE (close loop ventilation) and CLIP2 (cryopreserved platelets for surgical bleeding). Both are neutral trials at best, so we took them both pretty short. ACTiVE: https://pubmed.ncbi.nlm.nih.gov/41361939/...

Send us a Text Message (please include your email so we can respond!) Episode 83! Only one article this episode since Todd is feeling a little under the weather, but still a good discussion! ImmunoSep (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2842634 ImmunoSep (pubmed): https://pubmed.ncbi.nlm.nih.gov/41359996/ If you enjoy the show be sure to like and subscribe, leave that 5...

Send us a Text Message (please include your email so we can respond!) Back by popular demand, year in review! Or probably better titled "Our Favorite Articles of the Year" but I kept the title from last year. A smattering of papers and topics in this one ranging from avalanche survival, to intubation, to cardiac resuscitation and more.  Happy New Year everyone! We will see you in 2026, t...

Send us a Text Message (please include your email so we can respond!) Episode 81! In this episode we talk to Yonathan Fruend the senior author on the MODS study looking at a single questions approach to ruling out pulmonary embolism in the emergency department. This is not our typical patient population but this is a good episode, don't miss this one! MODS: https://pubmed.ncbi.nlm.nih.gov/411...

Send us a Text Message (please include your email so we can respond!) We start our Critical Care Reviews Down Under coverage with RSI talking with the first author of the "Ketamine versus Etomidate for Adults Receiving Emergency Endotrachael Intubation", Jonathan Casey! We will pick up the rest of our CCR Down Under Coverage after the holiday break! If you enjoy the show be sure to like...

Send us a Text Message (please include your email so we can respond!) Episode 79! We talk all about perfusion with arterial lines in EVERDAC and personalized resuscitation with ANDROMEDA SHOCK 2!  EVERDAC: https://pubmed.ncbi.nlm.nih.gov/41159885/ EVERDAC (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2502136 ANDROMEDA SHOCK 2: https://pubmed.ncbi.nlm.nih.gov/41159835/ ANDROMEDA SHOCK 2(JAMA): htt...

Send us a Text Message (please include your email so we can respond!) Episode 78! We start our discussion of the trials that drop with ESICM with the much anticipated BICAR-ICU 2! Then we talk briefly about some changes to the SOFA score with the new SOFA-2 score.  BICAR-ICU2: https://pubmed.ncbi.nlm.nih.gov/41159812/ BICAR-ICU 2 (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840824 SO...

Send us a Text Message (please include your email so we can respond!) Episode 77! We will start on ESICM coverage next episode. In this episode we talk about WFIT or "A Randomized Controlled Trial of a Post-ICU Telehealth Care Model" by Bakhru et al published in the blue journal September 2025! A long discussion but a good one! WFIT: https://pubmed.ncbi.nlm.nih.gov/40532205/ Editorial: h...

Send us a Text Message (please include your email so we can respond!) We were LIVE from the CHEST Annual Meeting 2025! Thanks to everyone who came out and stuck around to chat afterwards. We cover a lot of ground including some conference and Chicago related banter (~8 minutes if you wanted to skip to the learning!) High frequency oscillation: https://pubmed.ncbi.nlm.nih.gov/40983167/ MELLOW: http...

Send us a Text Message (please include your email so we can respond!) Episode 75! We talk about melatonin! We highlight MELLOW because it has the best acronym (by Burry et al in CHEST 2025). Then we dive into our mailbag! MELLOW: https://pubmed.ncbi.nlm.nih.gov/39800236/ DEMEL: https://pubmed.ncbi.nlm.nih.gov/40608082/ Meta-analysis: https://pubmed.ncbi.nlm.nih.gov/40662882/ If you enjoy the show...

Send us a Text Message (please include your email so we can respond!) Episode 74! We talk about the history and current practice of SBTs with "Providers Consistently Delay Extubation After Successful Spontaneous Breathing Trials" by Barker et al in Annals of the ATS and the original 1996 SBT article by Ely et al in NEJM. SBT: https://pubmed.ncbi.nlm.nih.gov/8948561/ SBT (NEJM): https://w...

Send us a Text Message (please include your email so we can respond!) We are (were) LIVE at ACNP Critical Care Bootcamp 2025! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about the PIC trial or "Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia" by Lemiale...

Send us a Text Message (please include your email so we can respond!) Episode 72! We continue talking about the articles from the CCR25 conference with UK-ROX or "Conservative Oxygen Therapy in Mechanically Ventilated Critically Ill Adult Patients" published in JAMA 2025 by Martin et al and TARGET-Protein or "Sodium bicarbonate therapy for patients with severe metabolic acidaemia in...

Send us a Text Message (please include your email so we can respond!) Episode 71! We continue talking about the articles from the CCR25 conference with FLUID or "A Crossover Trial of Hospital-Wide Lactated Ringer's Solution versus Normal Saline" published in NEJM 2025 by McIntyre et al and our old article is BICAR-ICU or "Sodium bicarbonate therapy for patients with severe meta...