Cassie Smith

Hormones, Metabolism & You!

Health EN ↓ 118 episodes

Your hormones control  everything —from energy levels to weight, mood, and overall health. But understanding them shouldn’t feel like decoding a medical textbook. Welcome to  Hormones, Metabolism & You! , the podcast where board-certified endocrinologist Dr. Cassie Smith breaks down the science behind your body’s most powerful regulators. Each week, Dr. Smith tackles the real questions about metabolism, weight management, thyroid health, menopause, PCOS, insulin resistance, and more—giving you clear, actionable insights to take charge of your health. Whether you’re struggling with stubborn wei...

Author

Cassie Smith

Category

Health

Podcast website

www.modern-endocrine.com

Latest episode

Jul 5, 2026

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Episodes

118: Stop Starving, Start Healing: The Real Root Cause of Weight Loss Resistance 05.07.2026

What if the reason you're struggling with weight, low energy, or hormone symptoms isn't just about eating less and exercising more?  In this episode, I sit down with functional medicine practitioner Dani Conway to talk about the bigger picture of metabolic health. We discuss why so many women are told their lab work is "normal" even when they still feel exhausted, inflamed, or stuck, and why looki...

117. Perimenopause Is Wild: Symptoms, Support, and What Actually Helps 28.06.2026

Perimenopause and menopause affect every woman, yet many are still caught off guard by the wide range of symptoms that can come with this stage of life. In this episode, I sit down with nutritionist, menopause researcher, and author Andrea Donsky to discuss what she's learned from studying thousands of women and why so many continue to feel confused, dismissed, or unsupported when seeking answers....

116: What Screen Time Is Really Doing to Your Eyes, Brain, and Stress Levels 21.06.2026

One of the most overlooked aspects of health may be influencing how you think, learn, focus, perform, and even respond to stress every single day. In this episode, I sit down with neuro-optometrist Dr. Bryce Appelbaum to explore the difference between eyesight and vision, and why seeing 20/20 doesn't necessarily mean your visual system is functioning optimally. We discuss how the eyes and brain wo...

115: PCOS Has a New Name: Why It’s More Than an Ovarian Disorder 14.06.2026

In this episode, I explain why PCOS is now better understood as Polyendocrine Metabolic Syndrome (PMOS). While the traditional name focuses on the ovaries, the reality is that this condition often extends far beyond reproductive health. I discuss why many women with PCOS don't actually have ovarian cysts, how the condition can affect everything from insulin and metabolism to cortisol, inflammation...

114. Why Your Brain Feels Drained... and How to Reset It with Dr. Patrick Porter 07.06.2026

In this episode, I sit down with Dr. Patrick Porter, founder of BrainTap and a longtime researcher in brain fitness and human performance, to explore why so many people today are struggling with brain fog, poor focus, low energy, and chronic stress. We discuss the relationship between the brain, gut, and nervous system, and how modern life may be affecting the way we think, feel, and function. Dr....

113: Why Cholesterol Isn’t the Villain and Estrogen Isn’t the Enemy with Dr. Terri DeNeui 31.05.2026

For years, cholesterol numbers have been treated as one of the primary indicators of heart health, but are we focusing on the right markers? In this episode, I sit down with Dr. Terri DeNeui to discuss the bigger picture behind cardiovascular risk. We talk through the limitations of looking at LDL cholesterol in isolation, the importance of factors like inflammation, insulin resistance, ApoB, lipo...

112: The Birth Control Conversation We Need to Have: Helpful Tool or Hidden Problem? 24.05.2026

What if the birth control pill you’ve been told is safe for decades is affecting far more than just pregnancy prevention? In this episode, I sit down with OB-GYN Dr. Johnny Peet for a powerful and nuanced conversation about oral birth control, hormone health, and the risks many women are never fully informed about, especially as they enter their 40s and 50s. We unpack the real differences between...

111: Beyond the Labs: The Metabolic Clues Behind Fatigue, Weight Gain & Thyroid Issues 17.05.2026

In this conversation, I sit down with Dr. James LaValle to unpack the deeper metabolic patterns driving symptoms like fatigue, thyroid dysfunction, weight gain, hormone imbalances, brain fog, inflammation, and low energy. We dive into why the body cannot be viewed as isolated systems and how stress hormones, insulin, gut health, thyroid function, sex hormones, and inflammation are all deeply conne...

110: Is Your Thyroid the Missing Piece? Dr. Amie Hornaman on Energy, Metabolism & Real Answers 10.05.2026

In this episode, I sit down with Dr. Amie Hornaman, also known as the Thyroid Fixer, to unpack the real reasons so many people struggle with fatigue, weight gain, brain fog, and hormone imbalances without getting clear answers. We dive into her personal journey of being misdiagnosed multiple times, what finally led her to answers, and why so many patients today are still being overlooked in tradit...

109: Why Gut Health Changes Everything: Dr. Vincent Pedre on Healing from the Inside Out 03.05.2026

This conversation completely changed the way I think about healing and I know it’s going to shift things for you too. In this episode, I sit down with Dr. Vincent Pedre to unpack why so many people are stuck dealing with fatigue, hormone imbalances, inflammation, brain fog, and digestive issues and why the real answer almost always comes back to the gut. We dive into his personal health journey, h...

108: Women, Weightlifting & Longevity: How to Build Muscle, Protect Hormones, and Age Well 26.04.2026

If you still think weightlifting is just about aesthetics, this conversation will completely change the way you see your body and your future. In this episode, I sit down with a highly experienced physician assistant and longtime strength training expert to unpack what women have been getting wrong about fitness for decades, especially in perimenopause and beyond. We dive into the real role of mus...

107: Why Doing More to Heal Can Backfire | The Cell Danger Response with Dr. Eric Balcavage 19.04.2026

In this conversation, I sit down with Dr. Eric Balcavage to unpack what’s really happening beneath the surface when your body feels stuck, overwhelmed, and unable to heal. We dive into the concept of the cell danger response and why so many people today are living in a chronic state of stress at a cellular level without even realizing it. We also explore the gap between traditional and functional...

106: Akkermansia: The Metabolism Microbe Every Woman Should Know 12.04.2026

What if everything you’ve been told about your metabolism is missing the most important piece? In this episode, I sit down with Dr. Colleen Cutcliffe to uncover the powerful and often overlooked connection between your gut microbiome, your hormones, and your metabolism. We dive into why so many women start experiencing stubborn weight changes, cravings, energy crashes, and insulin resistance, espe...

105: It Takes Two to Gaslight with Dr. E: A New Way to Understand Medical Dismissal 05.04.2026

You’ve been told everything is “normal”… but you know something isn’t right. In this episode, I sit down with Dr. Efrat LaMandre to unpack one of the most frustrating and isolating experiences in healthcare today: medical gaslighting. We dive into what it actually is, why it happens more often than we think, and the deeper systemic patterns inside medicine that lead providers to dismiss symptoms w...

104: Endometriosis Explained: Symptoms, Treatment, and What You Need to Know 29.03.2026

This episode is as raw as it gets as I open up about my personal journey with endometriosis and everything it has taken from me and taught me along the way. I share what it really feels like to live with pain that gets dismissed, the long road to diagnosis, and the emotional and physical toll this condition can have on your body, your relationships, and your future. Through my own story, I break d...

103: Stop Blaming Yourself: The ‘Normal Labs’ Trap + The Gut-Hormone Fix 22.03.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < What if doing everything “right” still leaves you feeling off because your health is not actually optimal? In this episode of Hormones, Metabolism, and You, Dr. Cassie S...

102: Your Mouth May Be Driving Inflammation - The Hidden Dental Link to Hormones Metabolism and Brain Fog with Dr. Michelle Jorgensen 15.03.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < What if one of the most overlooked drivers of inflammation, fatigue, brain fog, and hormone imbalance is something most people rarely think about… their mouth? In this episo...

101: Fix Your Gut, Fix Your Hormones: The Missing Links When Thyroid + Hormones Aren’t Enough 08.03.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < What if the reason you still feel tired after optimizing hormones is not your hormones at all? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with...

100: The Most-Shared Episodes on Thyroid, Hormones & Fatigue — The Answers Your Doctor Isn’t Giving You 01.03.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < In this special 100th episode of Hormones, Metabolism, and You, Dr. Cassie Smith celebrates the milestone with a best-of compilation featuring some of the most downloaded and impact...

99: Thinking About Peptide Therapy or GLP-1s? A Physician’s Safety Checklist for Women in Perimenopause & Menopause 22.02.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < What if peptides and GLP-1s are not the problem, but the internet hype is making it impossible to know what is actually safe, effective, and worth your money? In this episode of Hormone...

98: Perimenopause: The Gift We Didn’t Ask For and the Health Upgrade We Needed 15.02.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < What if perimenopause is not your body breaking down, but your body revealing exactly what it needs to function better? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith si...

97: Why Your Brain Must Feel Safe Before Detox Works: The Neurotoxic Loop of Trauma and Toxins 08.02.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < What if chronic illness protocols stall not because you are doing something wrong, but because your body does not feel safe enough to heal? In this episode of Hormones, Metabolism, and You, Dr....

96: Ayurveda for Perimenopause & Menopause: Gut Health, Estrobolome Support, and Anti-Inflammatory Spices 01.02.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < What if brain fog, bloating, exhaustion, and hormonal chaos are not separate problems, but signals of one shared root issue? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith is jo...

95: Why Dieting Fails in Midlife: Hormones, Insulin Resistance + Peptide Therapy 25.01.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < Doing Everything Right but Still Not Losing Weight? - The Shocking Truth About Midlife Metabolism - Learn How Hormones and Peptides Can Finally Unlock Fat Loss Without More Willpower If you feel like y...

94: Your Labs Are Normal but You Feel Awful - The Hidden Gut Inflammation Blocking Hormone Healing with Josh Dech 18.01.2026

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ < < What if your lingering thyroid and hormone symptoms aren’t a lab problem at all, but a gut inflammation issue hiding beneath “normal” results? In this episode of Hormones, Metabolism, and You, Dr. Cass...

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