Health & Veritas

Howie and Harlan are joined by Sandeep Jauhar, a cardiologist and the author, most recently, of the memoir My Father's Brain: Life in the Shadow of Alzheimer's . Harlan reports on new research about the timing of blood thinners for stroke patients with atrial fibrillation; Howie checks in on two physician groups that were acquired by private equity investors earlier this year and are now facing ba...

Howie and Harlan welcome Yale's Albert Ko back to the podcast to discuss the state of the COVID-19 pandemic and his career as an infectious disease specialist and public health researcher. Harlan reports on a breakthrough in pacemaker technology; Howie reflects on the complex relationship between obesity, social media, and mental health for young people.  Links: "A Dual-Chamber Leadless Pacemaker"...

Howie and Harlan are joined by Joseph Sakran, whose career as a trauma surgeon and advocate grew out of his own experience with gun violence. Harlan discusses his new study enumerating the vast scale of excess deaths among Black Americans; Howie reports on improvements in the insurance rate, nearly a decade after the Affordable Care Act went into effect.  Links: Harlan Krumholz: "Excess Mortality...

Howie and Harlan are joined by Josh Geballe, a Yale SOM graduate who serves as managing director of Yale Ventures, Yale's initiative overseeing the translation of research into impactful new companies. Harlan reports from the debate on AI in medicine; Howie reflects on the FDA's approval process for an over-the-counter birth control pill.  Links: "Iwasaki to Receive Else Kröner Fresenius Prize Sup...

Howie and Harlan are joined by Amanda Skinner, a Yale SOM graduate who leads Planned Parenthood of Southern New England. Harlan reflects on the potential and the dangers of artificial intelligence; Howie reports on an advisory from Surgeon General Vivek Murthy about the public health impact of loneliness and social isolation.  Links: "Five Alumni Named 2021-22 Donaldson Fellows" "Idaho hospital to...

Howie and Harlan are joined by Elizabeth Arleo, a radiologist with a focus on breast imaging and the author of  First, Eat Your Frog: And Other Pearls for Professional Working Mothers . Harlan reports on the state of AI in healthcare; Howie reflects on the epidemic of lung injuries from vaping.  Links: "Epic, Microsoft bring GPT-4 to EHRs" Harlan Krumholz: "Foundation models for generalist medical...

Howie and Harlan are joined by Megan Ranney, who will become the dean of the newly independent Yale School of Public Health later this year. Harlan reflects on the research that is helping us understand aging at a cellular level; Howie discusses a new study that he co-authored which examines the costs that make it harder for many mothers to breastfeed.  Links: "Accelerated Epigenetic Aging Is Asso...

Howie and Harlan are joined by Cary Gross, professor of medicine and public health and director of the National Clinician Scholars Program at Yale, to discuss his creative approach to research and his sometimes contrarian stances on cancer screening and not holding medical conferences in states that ban abortion. Harlan explains the nuances of new research about mortality risks tied to weight loss...

Howie and Harlan are joined by Michael Alosco, co-director of Boston University's Chronic Traumatic Encephalopathy Center, to discuss the consequences of years of hits to the head for football players and other athletes. Harlan reports on research that clarifies how to treat high cholesterol; Howie discusses a judge's ruling striking down coverage of preventative care. Links: "Treat-to-Target or H...

Howie and Harlan are joined by Helen Burstin to discuss her career examining issues of equity and quality in healthcare, and her current role as CEO of the Council of Medical Specialty Societies. Harlan reports on new research about the daily health effects of coffee; Howie looks at two investigations of misconduct by the insurance company Cigna.  Links: "Acute Effects of Coffee Consumption on Hea...

Howie and Harlan are joined by Michael Ivy, a surgeon and Yale New Haven Health's deputy chief medical officer, to discuss the mental health issues facing physicians and his own experience with burnout and depression. Harlan reports on new research casting doubt on the benefits of intermittent fasting; Howie explains how a new drug can help reduce the disproportionate rate of renal failure among p...

Howie interviews Harlan about his path to medicine and his career as a physician and scientist. Links:  Harlan Krumholz: "Community-acquired bacteremia in patients with acquired immunodeficiency syndrome: clinical presentation, bacteriology, and outcome" Harlan Krumholz: "Cost effectiveness of thrombolytic therapy with streptokinase in elderly patients with suspected acute myocardial infarction" H...

Howie and Harlan are joined by Ami Parekh, chief health officer of Included Health, which provides virtual care and data-driven guidance on finding the right doctor. Harlan reviews new research on alternatives to statins; Howie looks at the effect of mandated sick leave for screening tests like mammographs and colonoscopies.  Links: "Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant...

Howie and Harlan are joined by Brita Roy of NYU Langone Health to discuss her work drawing on the existing assets of a community to improve health outcomes. Harlan reports on new research on the dangers of sugar substitutes; Howie reflects on the growing openness to the lab-leak hypothesis for the origins of COVID-19.  Links: "The artificial sweetener erythritol and cardiovascular event risk" Harl...

Howie and Harlan are joined by health economist Anna Kaltenboeck, a graduate of Yale SOM's EMBA program who served as senior health advisor to the Senate Finance Committee during the development of the drug pricing reforms in the Inflation Reduction Act. Harlan reports on recent research on the timing of exercise; Howie reflects on the limitations of a blue-ribbon panel's recommendations on health...

Howie and Harlan are joined by Tara Lagu, a hospitalist, pharmacist, and researcher at Northwestern University, to discuss the startling bias faced by people with disabilities seeking care. Harlan reports on a study of attitudes toward genetic editing of embryos; Howie explains the debate over the looming shortfall in Medicare funding. Links: "Public views on polygenic screening of embryos" IMDB.c...

Howie and Harlan are joined by Jeffrey Sonnenfeld, an expert on leadership at the Yale School of Management, to discuss his decades of dialogue with top executives and his insights on healthcare leadership. Harlan reports on his new study exploring the causes of persistent hypertension; Howie reflects on CVS's acquisition of Oak Street Health and asks who benefits from recent innovations in the he...

Howie and Harlan discuss Howie's recent bout of COVID-19 and the takeaways from new research on adverse events in hospitals, and they consider claims from Tucker Carlson of Fox News about the pandemic response. Links: "5 COVID mistakes Biden's new chief of staff must admit" Harlan Krumholz: "A prescription for the US FDA for the regulation of health misinformation" "What older Americans need to kn...

Howie and Harlan are joined by Leora Horwitz, director of the Rapid Randomized Controlled Trial Lab at NYU Langone Health, to discuss her work using experimentation to improve the delivery of care, and her experience as a clinician and researcher in the chaotic first months of the COVID-19 outbreak in New York City. Harlan reports on his new study examining the impact on patients of early-morning...

Howie and Harlan talk with Gil Addo, CEO and co-founder of RubiconMD, which is aiming to expand access to specialty care by providing virtual consultations to primary care physicians. A new study from Harlan examines a loophole that is allowing unreliable medical devices to enter the market; Howie provides an update on legislature that will soon cause millions to lose Medicaid coverage. Links: Har...

Howie and Harlan check in on health issues that are in the news—or will be soon. Harlan discusses his work measuring patient outcomes and new avenues of research on long COVID; Howie reports on the perverse effects of private equity investment in specialty healthcare practices and the looming deadline facing state Medicaid programs.  Links: "What we learned about the NFL in the aftermath of Damar...

Harlan answers questions about the cardiac arrest suffered by Buffalo Bills player Damar Hamlin in a nationally televised football game; Howie reports on the rapid spread of the XBB 1.5 variant of COVID-19. And they are joined by F. Perry Wilson, a Yale nephrologist and an expert in the translation of medical research into clinical care, to discuss his new book,  How Medicine Works and When It Doe...

Howie and Harlan are joined by Lisa Sanders, the Yale internist who writes the "Diagnosis" column in the  New York Times.  Harlan reports on new studies demonstrating the ineffectiveness of ivermectin in treating COVID-19, and the effectiveness of the bivalent booster in improving outcomes. And Howie reacts to headlines about frequent misdiagnoses in emergency departments.  Links: "Effect of Iverm...

Harlan reports on a new study suggesting dramatic health benefits from bursts of vigorous activity; Howie explains how genetic science is starting to illuminate a mystery in his own medical history. And they are joined by Yale physician and scientist Jeffrey Gruen to discuss his work identifying the genetic variants associated with dyslexia and designing early interventions for kids with learning...

Harlan reports on new research on effective prostate cancer screening; Howie explores the potential of the AI language model ChatGPT. And they're joined by Dr. Kristen Nwanyanwu, a Yale ophthalmologist with a focus on closing the racial gap in the treatment of diabetic retinopathy. Links: "Prostate Cancer Screening with PSA and MRI Followed by Targeted Biopsy Only" Kristen Nwanyanwu: "Addressing D...