Health Newsfeed – Johns Hopkins Medicine Podcasts

NPTX2 is a protein that’s pivotal for helping your brain decide to remember certain things and forget others, and when levels of it decline it suggests that neurodegenerative processes like dementia may be beginning. That’s according to research by Paul … A protein that’s made in your brain at night helps you remember things, Elizabeth Tracey reports Read More »

Many theories on how brain disorders like Alzheimer’s disease begin point to proteins called amyloid beta and tau as accumulating and disrupting the function of neurons. Research by neuroscientist Paul Worley and colleagues at Johns Hopkins points to declining levels … How do neurodegenerative diseases begin? Elizabeth Tracey reports Read More »

You probably know how complex your brain function is, relying on a delicately balanced system full of proteins that act as signals and specialized nerve and structural cells. Turns out there is an interplay of some neurons being shut down … A change in a protein in the brain signals possible neurocognitive disorders, Elizabeth Tracey reports Read More »

NPTX2 is the abbreviation for a protein found in the brain that may allow much more accurate prognosis of who’s at risk for developing neurocognitive disorders, including Alzheimer’s disease and other dementias. That’s according to Johns Hopkins neuroscientist Paul Worley, … Accurately predicting who’s at risk to develop Alzheimer’s disease may now be easier, Elizabeth Tracey reports Read Mo...

Proteins known as tau and beta amyloid have been part of the dialogue on Alzheimer’s disease development for many years, with methods to measure them and drugs to remove them active areas of research. Another protein involved in the process … What can proteins in the blood and elsewhere teach us about developing dementia? Elizabeth Tracey reports Read More »

Sickle cell disease was thought to be cured using gene therapy, but longer term follow up reveals that while the condition improves many are not cured. Now a new approach developed at Johns Hopkins and around the world uses ‘half-matched’ … Sickle cell disease should be treated with a half-matched donor approach, Elizabeth Tracey reports Read More »

Gene therapy for sickle cell disease has a breathtaking price tag of 2-3 million dollars per person, and for some people who receive it, is doesn’t actually cure the condition. That’s according to Richard Brodsky, a sickle cell expert at … Gene therapy for sickle cell disease often isn’t a cure, Elizabeth Tracey reports Read More »

Headlines have announced that sickle cell disease can be cured with gene therapy. Now there’s a better way developed at Johns Hopkins and other centers around the world, using what are called ‘half-matched donors,’ to give new bone marrow to … A new technique is better than gene therapy for curing sickle cell disease, Elizabeth Tracey reports Read More »

Bone marrow transplants used to be limited to just those people with sickle cell disease who could receive bone marrow from a matched donor. Rick Jones, an expert in blood disorders and cancers at Johns Hopkins, and colleagues have just … A new technique cures most people with sickle cell disease, Elizabeth Tracey reports Read More »

Sickle cell disease is a genetic abnormality that causes red blood cells to sickle instead of being round, and a host of problems result, including excruciatingly painful sickle cell crises. Rick Jones, an expert in blood disorders and cancer at … What’s the best way to cure sickle cell disease? Elizabeth Tracey reports Read More »

Improvements in breast cancer detection and treatment have resulted in improved survival, but now those improvements seem to have stalled, a new analysis shows. William Nelson, director of the Kimmel Cancer Center at Johns Hopkins, says two groups of women … Breast cancer survival rates have stalled, Elizabeth Tracey reports Read More »

Immune checkpoint inhibitors are cancer drugs that for many have been a lifeline. Yet they are associated with a range of reactions that really need to be cataloged so they’re easier to recognize, some experts argue. Johns Hopkins Kimmel Cancer … Possible impacts of new cancer drugs need to be cataloged, Elizabeth Tracey reports Read More »

Microplastics you’ve inhaled and eaten are found all over your body, a recent study shows, and while no one knows exactly how they’re impacting your health, odds are they aren’t good for you. Kimmel Cancer Center director William Nelson at … How might microplastics be related to cancer risk? Elizabeth Tracey reports Read More »

Microplastics are formed from the breakdown of plastics in the environment, and they’ve now been found in many places in the human body, a new study reveals. William Nelson, director of the Kimmel Cancer Center at Johns Hopkins, says it’s … Your body has microplastics in many places, Elizabeth Tracey reports Read More »

Breathing through your mouth makes health issues from dryer air even worse, says David Edwards, a respiratory health expert at Johns Hopkins. His recent study shows the deleterious impact of dry air on our respiratory system but says there are … There are things you can do to help protect your respiratory health even with dryer air and poor air quality, Elizabeth Tracey reports Read More &#1...

Very tiny particles known as PM2.5 are a part of pollutants in the air, and have been shown to negatively affect health. Ditto for warming temperatures, which dry out our respiratory system, research by David Edwards, a respiratory health expert … How is poor air quality related to dry air and respiratory health? Elizabeth Tracey reports Read More »

Dry air just isn’t good for your respiratory health, new research by David Edwards, a respiratory health expert at Johns Hopkins, has shown. Dry air makes mucus thicker and harder to expel, and traps both toxins and pathogens in our … Does dry air contribute to more respiratory infections? Elizabeth Tracey reports Read More »

When you’re in an environment where the air is dry, a whole cascade of responses renders you more susceptible to respiratory conditions and diseases. That’s according to research by respiratory health expert David Edwards at Johns Hopkins. Edwards: It's understood … How are dry air and respiratory disease connected? Elizabeth Tracey reports Read More »

As our planet warms, relative humidity hasn’t changed much but evaporation rate has increased, so things are dryer. This is a prescription for increased respiratory problems, says David Edwards, a respiratory health expert at Johns Hopkins.  Edwards: We took airway … Dry airways and inflammation are linked, Elizabeth Tracey reports Read More »

Climate change and increasing temperatures are already taking a toll on your health, research by David Edwards, a respiratory health expert at Johns Hopkins, has shown.  Edwards: Airway mucosa is drying out, like the earth's top soil with warming temperatures, … What are increasing global temperatures doing to your airways? Elizabeth Tracey reports Read More »

Findings on a routine EEG called sleep spindles may be helpful in determining if a nonresponsive person who’s had a brain injury will recover, a new study reveals. Susanne Muehlschlegel, a critical care neurologist at Johns Hopkins, says this may … How is the decision on how long to continue life sustaining treatment made? Elizabeth Tracey reports Read More »

If someone has suffered a brain injury and is on life support, determining when to cease that treatment is challenging if they haven’t recovered consciousness, with a new study identifying something called sleep spindles, seen on EEG, as helpful. Johns … Is two weeks long enough to determine if someone will recover consciousness? Elizabeth Tracey reports Read More »

Deciding when to stop life sustaining treatment for someone who’s unconscious after brain injury may be easier now that a new study identifies sleep spindles, which can be seen on electroencephalograms, or EEGs, along with other testing, to predict who … How long should someone remain on life support? Elizabeth Tracey reports Read More »

Something called sleep spindles are spikes that show up in an electroencephalogram, or EEG, and may help predict whether someone  who’s had a brain injury will regain consciousness, new research shows. Johns Hopkins critical care neurologist Susanne Muehlschlegel says this adds … Sleep spindles may help discern who may regain consciousness, Elizabeth Tracey reports Read More »

When a patient is not responsive following a traumatic brain injury it is very difficult to tell when or if they’ll recover. A recent study may help by identifying characteristic tracings on an electroencephalogram, or EEG, that may be associated … It’s always a challenge when someone is unresponsive to determine how active their brain is, Elizabeth Tracey reports Read More »