Gut Podcast

Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Ms Rebecca Siegel, Scientific Director of Surveillance Research at the American Cancer Society. Ms Rebecca Siegel is first author on the paper 'Global patterns and trends in colorectal cancer incidence in young adults' published in Gut in December 2019. Read the article...

Dr Christopher Lamb, Clinical Intermediate Fellow at Newcastle University and Honorary Consultant in Gastroenterology at the Newcastle upon Tyne Hospitals NHS Foundation Trust discusses the BSG guidelines on the management of inflammatory bowel disease in adults with Associate Editor of GUT Dr Philip Smith. Read the article: https://gut.bmj.com/content/68/Suppl_3/s1

Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are lacking. The guideline discussed in this podcast is a joint initiative of the European Study Group on Cystic Tumours of the Pancreas, United European Gastroenterology, European Pancreatic Club, European-African Hepato-Pancreato-Biliary Association, European Digestive Surgery, and the European Society of Gastrointe...

Clostridium difficile (C. difficile, C. diff or CDI) is a bacterium associated with the intake of antibiotics which causes diarrhoea. It is easily spread to others, both in hospital and a household environments. C. Diff infections are generally treated with antibiotics. Recurrent infection is successfully treated with faecal microbiota transplantation (FMT), however the underlying mechanism of act...

Prioritising research and funding could have a significant impact on reducing colorectal cancer disease burden over the next 5 years. The conclusions are included in a study recently published by Gut titled “Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer” and expanded in this podcast. In conversa...

In this episode Mairi McLean, Associate Editor of Gut journal, talks to Matias Avila and Carmen Berasai, University of Navarra, Pamplona, Spain. They discuss their published paper "Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration". Full article >> http://gut.bmj.com/cont...

In this episode Mairi McLean, Associate Editor of Gut journal, talks to Fergus Shanahan, Professor and Chair of the Department of Medicine at University College Cork. They discuss his recent paper in Gut entitled "Feeding the microbiota: transducer of nutrient signals for the host" Full text - http://gut.bmj.com/content/early/2017/06/29/gutjnl-2017-313872

In this episode Mairi McLean, Associate Editor of Gut journal, talks to Benoit Chassaing, Georgia State University - Center for Inflammation, Immunity and Infection, about his recently published paper "Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation". Full paper>> http://gut.bmj.com/content/66/8/1414

In this episode Mairi McLean, Associate Editor of Gut journal, talks to Giovanni Cammarota and Gianluca Ianiro from the Agostino Gemelli University. They discuss the April editors choice paper "European consensus conference on faecal microbiota transplantation in clinical practice". Full paper >> http://gut.bmj.com/content/early/2017/01/13/gutjnl-2016-313017

In this episode Mairi McLean, Education Editor for Gut, talks to Dr Katja Breitkopf-Heinlein, Medical Faculty Mannheim, Heidelberg University, about her recently published paper "BMP-9 interferes with liver regeneration and promotes liver fibrosis". Full paper >> http://gut.bmj.com/content/66/5/939

In this podcast Mairi McLean talks to Professor Jon Rhodes about his recently published paper "Recent advances in clinical practice: a systematic review of isolated colonic Crohn's disease: the third IBD?" Full paper >> http://gut.bmj.com/content/66/2/362

In this episode Mairi McLean talks to Herbert Tilg about his recently published paper "Gut microbiome and liver diseases". Full paper >> http://gut.bmj.com/content/65/12/2035.long

In this podcast Mairi McLean interviews Dr Gianluca Ianiro about the editors choice paper "Antibiotics as deep modulators of gut microbiota: between good and evil." Full paper >> http://gut.bmj.com/content/65/11/1906.full?sid=4929814b-b6f1-43d2-9af1-964357aa664c

In this episode Mairi McLean talks to Professor Fock about his recently published paper; "Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett's oesophagus" Full paper >> http://gut.bmj.com/content/65/9/1402.full?sid=13ba6d1c-8c84-4ae9-9cd3-0bab0fa2b3a9

In this track Mairi McLean talks to Hasim El-Serag about the recent paper "Surveillance endoscopy is associated with improved outcomes of oesophagealadenocarcinoma detected in patients with Barrett's oesophagus."

In this podcast Dr Mairi McLean talks to Dr Sonia Friedman about the May editors choice paper "Live birth and adverse birth outcomes in women with ulcerative colitis and Crohn's disease receiving assisted reproduction: a 20-year nationwide cohort study". Full text > http://gut.bmj.com/content/65/5/767.full

In this podcast Dr Mairi McLean talks to Dr Mark Smits and Dr Djuna Cahen about their editors choice paper "GLP-1 based therapies: clinical implications for gastroenterologists"

In this podcast Dr Mairi McLean talks to Professor Dirk Haller about his editors choice paper "Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence." Read the full paper >> http://gut.bmj.com/content/65/2/225.full

In this podcast Dr Mairi McLean talks to Dr Christoph Gasche about his editors choice paper "Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2loxP/loxP Villin-Cre mice." Full paper >> http://gut.bmj.com/content/64/12/1905.full

In this podcast Dr Mairi McLean talks to Dr Joanna Jalanka about her recently published article in Gut entitled "Effects of bowel cleansing on the intestinal microbiota". They discuss what was already known in the field and what has since been discovered, and how long these effects last and how the microbiota were measured.

Mairi McLean talks to Thaddeus S Stappenbeck, Department of Pathology and Immunology, Washington University School of Medicine, about his paper: Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays. Read the full paper: http://goo.gl/xeWDHz

Helicobacter pylori strains that express the a protein that increases the risk of gastric cancer. However, the precise mechanisms through which the cancer risk is heightened have not been fully investigated and understood. In this podcast Dr Mairi McLean talks to Dr Lydia Wroblewski from the Vanderbilt University School of Medicine about the study her group conducted to define mechanisms through w...

Acute renal failure (ARF) is a common complication in patients with decompensated cirrhosis. The traditional diagnostic criteria of renal failure in these patients were proposed in 1996 and have been refined in subsequent years. More recently the International Club of Ascites (ICA)redefined the criteria to reach a new definition of acute kidney injury (AKI) in patients with cirrhosis. Dr Mairi McL...

Epigenetic alterations accumulate in normal-appearing tissues of patients with cancer, producing an epigenetic field defect. Cross-sectional studies show that the degree of the defect may be associated with risk in some types of cancer, especially cancers associated with chronic inflammation. Dr Mairi McLean speaks to Dr Toshikazu Ushijima about his study investigating these defects and the associ...

The genetic basis of inflammatory bowel disease (IBD) is incompletely understood, and the aim of a recent study in Gut was to identify rare genetic variants involved in the pathogenesis of IBD. Mairi McLean speaks to authors Sebastian Zeissig, Department of Internal Medicine I, University Medical Center Schleswig-Holstein, and Andre Franke, Institute of Clinical Molecular Biology, Christian-Albrec...