GU Cast | Urology Podcast

Prof Fred Saad (University of Montreal) drops in to chat about the interesting condition that is non-metastatic castration-resistant prostate cancer (nmCRPC). Which men are at risk of developing metastases? When should we use an AR pathway inhibitor? Why PSMA PET/CT should NOT be used. And hear his thoughts on "dabbling" in prostate cancer! Also joined by Professor Shankar Siva and Dr Lo...

What a great ESMO for GU Oncology!! Declan caught up with some plenary speakers in Madrid to discuss the biggest topics. PSMA theranostics with Louise Emmett (ENZA-P) and Oliver Sartor (PSMAfore); ARPIs in biochemical recurrence with Steve Freedland (EMBARK), Morgan Roupret and Boris Hadaschik. Plus the latest negative immunotherapy trials in prostate cancer with Christian Gratzke. Even better on...

The LuTectomy trial has just been published in European Urology, and as the GU Cast team have been very much involved, we thought we should dive into the details on today's podcast. LuTectomy is a clinical trial to evaluate the role of 177-Lutetium-PSMA prior to radical prostatectomy. Declan is the study co-PI along with Professor Michael Hofman, and Renu is first author on the LuTectomy pape...

One of our most popular episodes in 2022 was " Patting the Hormone Therapy Shark " with author, surfer and prostate cancer survivor, Tim Baker. And a lot has happened in the 12 months since so we invited Tim back for a follow-up chat in this Themed Podcast supported by our GU Cast Gold Partners, Mundipharma. Tim's inspiring approach to managing the side-effects of androgen deprivati...

We hijacked our good friends Professor Boris Hadaschik (Urologist, Essen, Germany), and Associate Professor Tyler Seibert (Radiation Oncologist, University of California, San Diego), who happened to be in Melbourne this week, and diverted them into the GU Cast studio for a chat about high-risk prostate cancer. Boris and Tyler were on a speaker tour supported Janssen Pharmaceuticals, so we put toge...

The European Association of Nuclear Medicine (EANM) Annual Meeting is the World's leading nuclear medicine extravaganza! Today we cross live to Professor Michael Hofman and friends to hear some of the GU highlights at this year's annual meeting in Vienna.  Michael is joined by Prof Ken Herrmann, Dr Kerry Jewell, Dr Francesco Ceci, Dr Phiilip Kuo, Dr Bastiaan Privé and Dr Wolfgang Fendler...

The mass media were quick to pick up on two papers in JAMA Surgery last week with headlines such as "Patients have better outcomes with female surgeons", and "Should you pick the sex of your surgeon?". So what's it all about?? We chat with lead author of one of these papers. Dr Chris Wallis, Urologist at the University of Toronto, whose looked at outcomes for more than 1.2...

Is this the solution to screening for prostate cancer?? Don't bother with a PSA test and instead screen using a 10 minute MRI scan??! Re-IMAGINE is a very interesting prospective study published in BMJ Oncology this week which did exactly that with some really interesting findings. We are joined by study authors Professor Caroline Moore and Professor Shonit Punwani to discuss. Even better on...

What is a rectal spacer and do they help reduce side-effects from prostate radiation??! That's today's topic on GU Cast. Renu caught up with rectal spacer enthusiasts Professor Peter Orio (Dana Farber Cancer Institute) and Associate Professor Shankar Siva (Peter MacCallum Cancer Centre) in downtown Melbourne this week to learn all about this topic. Thanks to our friends at Icon Cancer Ce...

Here's a quick plug for another podcast that GU Cast is very happy to support! Launching in September 2023, the European Urology Podcast is a new monthly podcast to accompany the world's highest ranked urology journal, European Urology. Co-hosted by Professor Declan Murphy in Melbourne and Dr Joyce Baard in Amsterdam, the European Urology Podcast will highlight key papers and feature int...

Major scientific journals only change their Editor-in-Chief every 8-10 years so it's quite a big deal when it happens! Today we chat with Professor Alberto Briganti, incoming Editor-in-Chief of European Urology,  the world's highest ranked urology journal, and with Professor Morgan Roupret, incoming Editor-in-Chief of European Urology Oncology. Why has everybody's impact factor drop...

Declan and Renu as you haven't seen them before! They leave their cosy  podcast studio to do battle at the Australia & New Zealand Urogenital & Prostate Trials Group (ANZUP) Annual Scientific Meeting! The battleground is renal cancer, with Renu arguing in favour of adjuvant immunotherapy, and Declan arguing against. No holds barred. Who wins??! Tune in to find out. Plus we chat with s...

This, our 100th episode, is a very special GU Cast, in which we remember the devastating 2011 Christchurch earthquake, which hit just as the Urological Society of Australia & New Zealand (USANZ) Annual Scientific Meeting (ASM) was kicking off in the city. 185 people lost their lives with many thousands injured, and with huge devastation across the region. Declan returned to Christchurch recent...

This is for hardcore PSMA aficionados!! This is the 7th of our ProsTIC/Prostate Cancer Foundation Global Webinars focussing on all things PSMA theranostics (you can find the rest in our back catalogue stretching back to April 2020). We peek into theranostics beyond what we currently have with beta-emitters like LuPSMA, into the tantalising world of alpha-PSMA theranostics. Multidisciplinary resear...

Dr Sima Porten from the University of California San Francisco (UCSF), was in Melbourne this week for the ANZUP Annual Scientific Meeting (more from that in an upcoming episode), so she popped into the GU Cast studio to chat with Renu and Declan. Renu of course spent a year with Sima and colleagues doing Fellowship training in GU Oncology so she was very happy to have her good friend and mentor in...

Two cracking bladder cancer studies to discuss on GU Cast today (in our brand new GU Cast studio)! We are joined by Dr Sia Daneshmand, Urologist and Director of Urologic Oncology at the University of Southern California, who presented the headline-making Tar-200/SunRIse-1 study at the recent Annual Meeting of the American Urological Association. Not sure what a urological pretzel is and how it can...

Stereotactic Ablative Body Radiotherapy (SABR) has been a great tool for managing low volume metastatic prostate cancer for a few years now. One or two visits to the radiation centre, highly targeted, minimal side-effects. So could it be used to treat the primary prostate cancer itself with similar success? Today we have top SABR experts Dr Alison Tree (Royal Marsden Hospital, London), and Associa...

With approvals and reimbursement increasing all the time for the use of AR pathway inhibitors (ARPIs) in metastatic hormone-sensitive prostate cancer (mHSPC), we chat today about how front-line clinicians need to make sure we are making the most of these opportunities for our patients. Urologists in particular are the clinicians who most frequently diagnose men with metastatic prostate cancer, and...

So if you haven't seen all the fuss about ChatGPT on social media in the past two weeks, then imagine this. You have to write a 500 word introduction to an article on adjuvant therapy following renal cancer surgery, you are a week past deadline and  you have writer's block. Or it's your thankless task to organise next year's on-call roster for your Department. Or your year 11 s...

The annual Prostate Cancer Foundation (PCF) Retreat is in its 29th year, and is the showpiece event of the PCF's incredible research program. Each year, PCF investigators from around the world gather in California to share their work and interact together. Fair to say it has developed a legendary status among the prostate cancer community across the globe. GU Cast's Dr Renu Eapen has rec...

Is grade group 1 (Gleason 6 in old money) really prostate cancer? Wouldn't life be a little easier for patients (and the rest of the world) if we could somehow remove the label "cancer" from this relatively indolent condition?? Well this decade-old discussion seems to have developed a lot of momentum in the past year, driven by urologists like Dr Scott Eggener (University of Chicago...

A GU Cast Ireland Special! Declan recently travelled to the Annual Meeting of the Irish Society of Urology and posted this GU cast special from Killashee House in County Kildare. Apologies in advance for him wallowing in his Irishness!  Declan catches up with Urologists David Bouchier-Hayes, Eva Bolton, Catherine Dowling, and Richie Power, to chat about everything from Terence Millen and Peter Fre...

OK this episode of GU Cast is essential listening for anyone who has anything to do with androgen deprivation therapy (ADT), or "hormone therapy", for men with advanced prostate cancer. Whether you are a prescriber (especially if you are a prescriber), nurse or allied health professional, patient, loved one, industry representative, or researcher - this is one not to miss. Tim Baker is a...

"Prostate Specific" Membrane Antigen PET/CT - now also available to stage kidney cancer! We seriously need a name change here. Already we know that PSMA PET/CT shows a lot more than the prostate/prostate cancer, but could it have utility in staging renal cancer?? We've certainly had a lot of off-trial experience of this at Peter MacCallum Cancer Centre since 2014, and we know see da...

A great episode focussing on two aspects of bladder cancer. Bladder preservation for muscle-invasive cancer is in the limelight again following the recent update of the landmark BC2001 trial. We chat with bladder cancer gurus Dr Neha Vapiwala, Radiation Oncologist at the University of Pennsylvania, Dr Ashish Kamat, Urologist at MD Anderson Cancer Centre, and Dr Nathan Lawrentschuk, Urologist at Pe...