Gladden Longevity Podcast

In this episode, Dr. Marc Pietropaoli discusses his transition from traditional orthopedics to regenerative medicine, emphasizing the importance of repairing rather than replacing damaged joints. He shares insights on the components and sequencing of regenerative treatments, the role of genetic testing in nutrition, and his mission to eliminate the need for knee replacements by 2043. The conversat...

In this conversation, Dr. Kevin R. Stone discusses his journey and innovations in cartilage regeneration, focusing on the importance of mindset, the role of anabolic therapies, and the significance of play in recovery and longevity. He emphasizes the need for a holistic approach to injury prevention and recovery, encouraging patients to view their injuries as opportunities for improvement rather t...

In this episode of the Gladden Longevity Podcast, Dr. Gladden and Leslie Kenny delve into the intricacies of aging, health, and the role of spermidine in promoting longevity. They discuss the hallmarks of aging, Leslie's personal journey with autoimmune conditions, and the importance of empowerment and curiosity in health management. The conversation emphasizes the interconnectedness of health fac...

Dr. Pamela Cipriano shares her journey from being an ICU nurse to a trailblazer in functional medicine. She discusses her personal experiences with Lyme disease, the importance of hydration, nutrition, and the impact of chronic illnesses. Dr. Cipriano emphasizes the need for a holistic approach to health, focusing on root causes and lifestyle changes, while also sharing insights on the effects of...

In this episode of the Glad and Longevity Podcast, Jeff Gladden and Jonathan Roseland delve into the world of biohacking and nootropics. They discuss the inspiration behind Roseland's journey into cognitive enhancement, the quest for effective smart drugs, and the role of nicotine in boosting creativity. The conversation also touches on the importance of a systems biology approach to personal deve...

In this conversation, Dr. Aleksandra Gajer shares her journey from emergency medicine to focusing on metabolic health and hormonal balance. She discusses the challenges faced during the COVID-19 pandemic, her transition to a new practice, and the importance of understanding metabolic health as a foundation for overall wellness. Dr. Gajer emphasizes the role of peptides in supporting health, the si...

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden speaks with Nicole Bell and Jennifer Miller from Galaxy Diagnostics about the challenges and advancements in diagnosing and treating tick-borne illnesses, particularly Lyme disease. They discuss the personal journey that led Nicole to become the CEO of Galaxy Diagnostics, the complexities of the immune response to Lyme, and the...

In this conversation, Ashley James shares her journey as an anxiety cessation expert, discussing her personal experiences with ADHD and anxiety. She emphasizes the importance of personal growth and the tools she has developed over 20 years to help others manage their anxiety. The discussion covers the role of genetics, the physiological responses to stress, and the difference between excitement an...

In this episode, Dr. Gladden and nutrition expert Sarah Kennedy discuss Calocurb , a natural extract that uses evolutionary biology to suppress appetite. The discovery focuses on bitter taste receptors (T2Rs) located throughout the gastrointestinal tract, which historically served as a protective mechanism to slow the consumption of potentially toxic substances. By using a specific New Zealand hop...

In this episode of the Gladden Longevity Podcast, Garrett Salpeter discusses his journey in developing the NeuFit device, which combines principles of engineering and neuroscience to enhance healing and athletic performance. He shares insights on the role of the nervous system in recovery, the importance of neuromuscular reeducation, and how electrical stimulation can be used to balance muscle act...

In this episode, I break down the three things that determine whether your supplement protocol is actually working or quietly wasting your time and money. Most people are worried they're not taking the right thing, not taking the right amount, or worse, taking something that's actively counteracting something else in their stack. That's not paranoia. It's a real problem. I walk through the first p...

In this episode of the Gladden Longevity Podcast, Dr. Jeff Gladden, Dr. Oscar Coetzee, and Danielle Arnold delve into the complexities of the gut microbiome, discussing its role as an organ system, the importance of probiotics and prebiotics, and the impact of modern diets on gut health. They explore innovative technologies for enhancing gut health, the significance of microbiome diversity, and th...

In this episode of the Gladden Longevity Podcast, Jeff Gladden and Jason Sonners delve into the fascinating world of hyperbaric therapy. Jason shares his personal journey from experiencing a debilitating disc injury to discovering the profound benefits of hyperbaric oxygen therapy. They explore the science behind oxygen's role in cellular function, the therapeutic effects of hypoxia, and the impor...

In this episode, I break down the major categories of medicine— allopathic, functional, naturopathic, ayurvedic, Chinese, homeopathy, and integrative—explaining what each does well and where each falls short. I then show why longevity medicine goes further by treating aging itself as the root cause. You'll learn how the 12–16 hallmarks of aging accelerate each other, why symptom management or root...

In this episode of the Gladden Longevity Podcast, Dr. Elizabeth Yurth shares her extensive journey in the longevity and regenerative medicine space, discussing the evolution and significance of peptides in healing and performance. She emphasizes the importance of understanding hormonal and peptide levels as we age, the role of mitochondria in energy production, and the critical aspects of immune r...

In this conversation, Eli Israel shares his journey with longevity and optimization, focusing on his experiences with Crohn's disease, cancer, and the transformative impact of surgery. The discussion delves into the psychological burdens of chronic illness, the importance of mindset, and the role of courageous conversations in relationships. Mukti Devi emphasizes the significance of embracing unce...

In this exciting episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden joins Kyle Trautmann to explore the fundamental electrical underpinnings of human vitality. Moving beyond basic biochemistry, they dive into energy literacy and the critical role of cellular energy in the pursuit of longevity. The conversation reveals how maintaining proper voltage within the body is essential for mitoc...

In this episode, Dr. Jeff Gladden walks through a live stress and nervous system assessment with Carlos, a 29-year-old patient who has survived five accidents including three serious ones. Dr. Gladden breaks down what heart rate variability actually measures, why your stress index reveals how fast you're aging, and what vagus nerve power means for longevity. He explains why all of life comes down...

In this compelling episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Dr. Lloyd Glauberman explore how the subconscious mind fundamentally dictates our longevity. They dive deep into Hypno-Peripheral Processing (HPP), a unique method designed to bypass the conscious ego and install healthy lifestyle habits directly into the subconscious. By leveraging the brain's natural neuroplasti...

In this transformative episode of the Gladden Longevity Podcast , Dr. Jeffrey Gladden and Sara Fisk dive deep into the essential connection between authentic relationships and long-term health. While many focus solely on physical biohacking, this conversation reveals that longevity is profoundly impacted by our ability to navigate societal expectations and foster meaningful connections . Sara and...

In this episode, I break down the six developments I'm watching in longevity for 2026 and why I believe we're closer than ever to cracking the code on aging. I explain how AI is already transforming personalized medicine (and how to prompt it for better results), introduce the Longevity Wingman app we're building to remove all friction from your health journey, and discuss why genetic testing is f...

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and neurologist Dr. Majid Fotuhi discuss building an "Invincible Brain." Challenging the myth that cognitive decline is inevitable, Dr. Fotuhi outlines five pillars—exercise, sleep, nutrition, stress management, and brain training, proven to increase brain volume and neuroplasticity. The discussion highlights how racket sports a...

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden sits down in person with fitness and nutrition expert Autumn Calabrese to unpack the full truth about GLP-1 agonists. With millions of people jumping on semaglutide, tirzepatide, and soon retatrutide, the conversation most doctors aren't having is about what's actually happening inside the body while the scale goes down. Dr. Gla...

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden speaks with registered dietitian Ashley Koff about her personal journey with body image, trauma, and the importance of understanding weight health. They discuss the psychological aspects of health, the role of medications in weight management, and the significance of personalized nutrition. The conversation emphasizes the connec...

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden speaks with Dr. Anthony Beck about the evolving landscape of functional medicine and the importance of personalized health approaches. They discuss the challenges patients face in navigating conflicting health information, the significance of integrating multiple health assessments, and the role of genetics in understanding indi...