GasGasGas - Anaesthetic Science for Anaesthesia!

Tom and James wade through Liver physiology, debrief afterwards when we try and devise a way to talk about this functions without listing out something written on our arms! Check out the show-notes at gasgasgas.uk/liver ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics...

Classifying Hypoxia, Oxygen delivery and taking oxy-haemoglobin Sat Curves Tom gets quizzed on what defines hypoxia, how oxygen is delivered to tissues and how the oxyhemoglobin disassociation curve behaves. Shownotes on gasgasgas.uk ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me...

Tom talks cardiac physiology, exploring blood pressure, Hagen–Poiseuille law, and coronary blood flow, finishing up with a brief chat of the cardiac cycle. There is a debrief and extra detailing at the end in very quick fire ‘words that convey you know what you’re on about’ sot of standing. Show notes here! ================================================ GasGasGas - Covering Anaesthetic Science f...

This viva cast takes Tom on an epic battle, sundering his way through the VIE, crossing the Wheatstone Bridge, looking around corners with Fibre Optics and finally zapping everyone with Lasers. Show notes @ gasgasgas.uk/vivacast_8 ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me An...

Tom experiences some catecholamine release of his own in this episode as he talks serpiginous GPCRs, Adenyl cyclase, PKA and comparing local anaesthetics, and getting tied up (like we all do) with the clinically pointless, but delightfully examinable Vaughan-Williams Anti-arrythmic classes! We Debrief and break into some of the questions as we go. As always the show notes are on the website! =====...

Tom dives into the critical details of how oxygen makes it to the mitochondria, tells me of this concept called shunt and then gets thoroughly beaten to shreds by the Valsalva manoeuvre - a tactical doozy that gets rolled out because it is a baffling set of steps. Alveolar Gas Equation Shunt Hypoxic Pulmonary Vasoconstriction Oxygen concentration Sensing of Plasma And the Valsalva Manoeuvre. We De...

This VivaCast episode assesses Tom as we explore the structured approach to a clinical viva station requiring conversation around delivering an anaesthetic. Show notes @: https://gasgasgas.uk/frca-clinical-viva-laparotomy/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaestheti...

This Podcast for the FRCA Primary Exam thoroughly explores what is going on within the multi compartmental model that we use to try and comprehend how drugs move through humans. If you like this, leave me a comment, if you don't, also leave a comment it's a rather mad one - perhaps reflected in the build up to this over the last few episodes. Show notes @: https://gasgasgas.uk/multi-compartmental-...

Willing Victim Tom wields his knowledge Vs Dr Gas SVP - Humidity - Critical Temperature Heat and Temperature (James defines the 4 laws of thermodynamics) Vapourisers and their function + Sevo vs Des Entonox Vs Nitrous Oxide  Gas Laws Finishing with a novel... way to recall gay-lussac law. Show notes @: https://gasgasgas.uk/physics-heat-humidity-gases/ ==============================================...

This Podcast for the FRCA Primary Exam is the first part in a series covering the multi compartmental mode. It Introduces Half-lives and Time Constants, how they bear out influencing clearance and offset times and bi-exponential decay. Show notes @: Poly-Compartmental madness part one ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Spons...

Willing Victim Tom wields his knowledge Vs Dr Gas Show Notes @: https://gasgasgas.uk/paralysis-suxamethonium-rocuronium-reversal/ How Carbon dioxide is transferred from tissue to atmosphere The influences Carbon Dioxide, Oxygen, Mechanical and Drug factors have on intra-cranial pressure Closing out with how the neonatal gasp and umbilical cord clamp triggers a number of cardio-vascular events in t...

Willing Victim Tom wields his knowledge Vs Dr Gas Shown notes @ : https://gasgasgas.uk/frca-physiology-viva-podcast-co2-icp-neonatal-physiology/ How Carbon dioxide is transferred from tissue to atmosphere The influences Carbon Dioxide, Oxygen, Mechanical and Drug factors have on intra-cranial pressure Closing out with how the neonatal gasp and umbilical cord clamp triggers a number of cardio-vascu...

Welcome to the first episode that emulates the primary FRCA viva (bar the drawing). This crack at interview style podcast covers sterilisation and cleaning of medical equipment, one of the many viva curveballs! Show Notes @: https://gasgasgas.uk/frca-viva-cleaning-and-sterilisation/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsor...

This FRCA Primary Exam Podcast discusses Suxamethonium, its action, uses and pharmacology as well as an intro to neuromuscular blockade monitoring and cholinesterase deficiency. Shownotes @ : https://gasgasgas.uk/suxamethonium-for-the-frca-primary-exam/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Ch...

This FRCA Primary Exam Podcast analyses Morphine and the opiate receptors, the mechanisms, pharmacokinetics, pharmacodynamics and puts its use into context. Shownotes @ : https://gasgasgas.uk/morphine-for-the-frca-primary-exam/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaes...

This FRCA primary exam podcast explores the kinetics and dynamics of Ketamine, describes the NMDA receptor in detail and discusses the clinical uses of ketamine in UK anaesthetic practice. Shownotes @ : https://gasgasgas.uk/ketamine-for-the-frca-primary/ Read this from dec 2025: https://www.thebottomline.org.uk/summaries/icm/rsi-ketamine-or-etomidate-for-tracheal-intubation-of-critically-ill-adult...

A Brief intro as to why I am doing this podcast, and introducing the viva-cast subseries coming soon! ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate] Contributions to keep the lamps lit here ==============================================...

This episode focuses on drawing comparisons between the different volatile anaesthetic agents  Shownotes @ : https://gasgasgas.uk/gasgasgas-comparing-volatiles/ Specifically : Comparisons between the blood gas partition coefficient their oil gas partition coefficient the boiling points and saturated vapour pressure differences and we’re going to define those two points a little bit and then also t...

Today we're covering more volatiles, thinking a bit more about the defining characteristics of volatiles and exploring MAC, Minimum alveolar concentration. Including MAC BAR and MAC Awake - and what you really need to aim for to make sure no one remembers having their insides rummaged about in by a surgeon! Show notes @: https://gasgasgas.uk/mac-and-anaesthetic-depth/ =============================...

The whirlwind that is enzyme kinetics in the human body for the FRCA primary exam, Enjoy! Show Notes @: https://gasgasgas.uk/michaelis-menten-enzyme-kinetics/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource [affiliate] Contributions to keep the lamp...

FRCA Primary Podcast looking at the properties of Atracurium, further introduction to the action of neuromuscular blocking agents and that all important exam structure! Shownotes @ : https://gasgasgas.uk/gasgasgas-atracurium-frca/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me An...

Talking Thiopentone, the bits needed for the exam and the practical bits of when it might get used (rarely, unless the boss happens to be from the 1940's) or you're doing obstetrics. Shownotes @: https://gasgasgas.uk/thiopentone/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Ana...

This episode explores how volatile anaesthetics behave and affect patients. Chiefly thinking about how the compartments in a breathing circuit and patient interplay to achieve depth / maintain anaesthetic depth and emerge from anesthesia. Absolutely worth a listen to get your head around compartments and also starting thinking about blood gas and oil gas partition coefficients Show notes @: https:...

This primary FRCA podcast episode introduces clearance and then descends into bedlam trying to think about how the liver really clears drugs on a kinetics level. Shownotes @: https://gasgasgas.uk/hepatic-clearance/ I am not making you run for the hills by talking phase 1 and 2 metabolism, CYP and all that jazz, that's for a later episode. ================================================ GasGasGas ...

We're talking pKa and all the delightful brain strain associated (or disassociated!) from it pKa is a concept which is critical to how drugs cross membranes to their respective active sites. Shownotes @: https://gasgasgas.uk/what-is-pka-frca-primary-podcast/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaestheti...