Endocrine News Podcast

The Endocrine Society recently released a new Clinical Practice Guideline (CPG) on Central Precocious Puberty . Among its many recommendations, the CPG says some subgroups of children with precocious puberty—such as older girls with slowly progressing puberty—may not need the same level of testing or treatment. Central precocious puberty happens when a child’s brain activates puberty-related hormo...

The U.S. Food and Drug Administration recently qualified "total hip bone mineral density" as a surrogate endpoint to support clinical trials for osteoporosis drugs. This decision will significantly impact clinical trials moving forward, as the traditional endpoint of "fracture outcomes" presented many challenges regarding sample size, duration, and cost. The change came about because of findings f...

The endocrine workforce shortage is affecting the lives of endocrinologists and the patients they treat. Many practices would benefit from any support that would give endocrinologists more capacity to focus where they really need to. Could advance practice providers, such as nurse practitioners and physicians assistants, be able to provide that support if they had a little more training?   The End...

There is a lot of interest in automated insulin delivery systems, and they were covered in depth at the Endocrine Society’s Type 1 Diabetes Fellows Series, held earlier this year. Joining host Aaron Lohr to talk about these delivery systems is Grazia Aleppo, MD, a professor of medicine at Northwestern University and a presenter at the T1D Fellows Series. Show notes are available at https://www.end...

There are plenty of studies showing that chemicals found in the environment can directly impact human health. Some new research finds that certain environmental compounds may trigger early female puberty. Joining host Aaron Lohr to talk about that research is Natalie Shaw, MD, a Lasker clinical research scholar and principal investigator of the pediatric neuroendocrinology group in the Clinical Re...

It’s been a few years, but we are here with an update on acromegaly, covering prevalence, diagnosis, traditional treatment, new therapies, and current gaps in understanding. Host Aaron Lohr talks again with Maria Fleseriu, MD, professor of medicine and professor of neurological surgery at Oregon Health & Science University School of Medicine and director of OHSU’s Pituitary Center. Dr. Fleseriu al...

Host Aaron Lohr talks with Rita Kalyani, MD, professor of medicine at Johns Hopkins University School of Medicine and president-elect of medicine and science at the American Diabetes Association. Earlier this year, Dr. Kalyani and colleagues published a position statement in The Journal of Clinical Endocrinology & Metabolism titled, “Prioritizing Patient Experiences in the Management of Diabetes a...

In this episode, we talk about pheochromocytomas. Host Aaron Lohr talks with Nikhitha Chandrashekar, MD, who recently finished her endocrinology fellowship at University Hospitals Case Western Reserve University in Cleveland. Dr. Chandrashekar presented a case study on pheochromocytomas at ENDO 2024. Show notes are available at https://www.endocrine.org/podcast/enp92-pheochromocytomas — for helpfu...

Our bodies typically do a remarkable job of recovering from certain injuries, and thyroid hormone signaling has an essential role to play there. But what is that process like for someone with hypothyroidism, and is there a unique role in that process for muscle stem cells? Host Aaron Lohr talks with Paola Aguiari, PhD, a senior research specialist at Children’s Hospital Los Angeles. She presented...

We all know that stress leads to a number of negative outcomes. In this episode, we talk about how early life stress may influence youth substance use initiation and some endocrine factors that may be helping to drive that influence. Host Aaron Lohr talks with Alexandra M. Donovan, PhD, of the Charles R. Drew University of Medicine and Science. Dr. Donovan recently presented an abstract at ENDO 20...

In this episode, we talk about brown fat and some new discoveries in how it regulates metabolic function. Joining host Aaron Lohr is Marsel Lino, PhD, a research fellow at Joslin Diabetes Center in Boston. Dr. Lino presented an abstract at ENDO 2024 titled, “A New Layer of Endocrine Regulation: Brown Fat Secretes Exosomal MicroRNAs, Which Regulate Metabolic Functions and Distal Organs.” Show notes...