Decera Clinical Education Infectious Disease Podcast

In this episode, global PrEP experts and advocates discuss barriers that have prevented the full potential of today’s PrEP regimens from being delivered, how those barriers might be overcome, and how the next generation of PrEP modalities may address unmet needs, including:  How access and implementation of PrEP have limited its benefit and led to disparities in uptake among racial and ethnic grou...

In this episode, Richard Colgan, MD, discusses the burden of uncomplicated UTIs (uUTIs) and best practices in their management, including: Accurate diagnosis and classification Risk factors for uUTIs and treatment failure Burdens of uUTIs on patients Innovations in care, including self-diagnosis and virtual management The importance of avoiding screening and management of asymptomatic bacteriuria...

In this episode, Lilly C. Lee, MD, SM, FACEP, FAAEM, discusses the best practices in management of uUTI in the emergency department, including: Patient triage Diagnostic stewardship Interdisciplinary care Strategies to overcome treatment barriers Presenter : Lilly C. Lee, MD, SM, FACEP, FAAEM Chief of Emergency Medicine Jackson Memorial Hospital Florida Poison Information Center Roxcy Bolton Rape...

In this episode, Lillian Abbo, MD, MBA, FIDSA, discusses appropriate antimicrobial selection for managing uncomplicated UTIs, including: Balancing discrepancies in available guidelines  Individualizing antimicrobial selection based on patient characteristics and local resistance patterns  Incorporating tools, like antibiograms, into daily practice  Being a good steward of currently available antim...

In this episode, Atul Humar, MD, FRCP(C); Hannah Imlay, MD, MS; and Raymund Razonable, MD, discuss cytomegalovirus (CMV) management strategies in solid organ transplantation recipients, including: Evaluation of current data on CMV prevention in liver transplant recipients Practical considerations for switching an institution’s antiviral therapy of choice for primary prophylaxis Barrier of resistan...

In this episode, Hannah Imlay, MD, MS, discusses cytomegalovirus (CMV) prevention strategies in solid organ transplantation (SOT) recipients including: Strategies for preventing CMV in SOT International guideline recommendations for CMV prevention strategies by organ type Antivirals used for CMV prevention Comparison of preemptive therapy vs prophylaxis for CMV prevention in liver transplant recip...

In this episode, Raymund Razonable, MD, discusses cytomegalovirus (CMV) management strategies beyond primary prophylaxis in solid organ transplantation recipients including: CMV treatment goals  CMV treatment and monitoring recommendations Role of secondary prophylaxis Use of CMV cell–mediated immunity (CMI) monitoring for CMV relapse risk Use of CMV CMI for secondary prophylaxis  Proposed use of...

Arthur Kim, MD, and Renslow Sherer, MD, discuss how new data on COVID-19 vaccines and treatments may affect practice, including: Real-world data on COVID-19 outcomes COVID-19 prevention: current and emerging concepts COVID-19 therapeutics: new clinical trial and real-world data Presenters: Arthur Kim, MD Associate Professor of Medicine Harvard Medical School Division of Infectious Diseases Massach...

In this first of 3 episodes, global HIV experts and advocates discuss how innovative models of care are minimizing barriers to HIV care engagement to improve uptake by key underserved populations, including: How peer support programs empower people to combat stigma, become more educated about treatment, and be engaged participants in their HIV care Strategies for addressing potential unmet mental...

In this episode, Shannon Kasperbauer, MD, discusses guideline-based treatment recommendations for people with  M. abscessus , including a discussion of: Macrolide resistance Predictors for disease progression 2020 NTM guideline recommended treatment options Emerging therapies We will also hear from a patient who describes how she remained adherent during long courses of treatment for  M. abscessus...

In this episode, Charles L. Daley, MD, discusses guideline-based treatment recommendations for nontuberculous mycobacterial (NTM) lung disease, including treatment regimens for: Mycobacterium avium complex M. kansasii M. xenopi We will also hear from a patient who describes the use of airway clearance devices and a patient who describes his typical NTM treatment course. Finally, we hear Dr. Daley...

In this episode, Pamela J. McShane, MD, describes the 3 pillars for nontuberculous mycobacterial (NTM) lung disease diagnosis: Clinical symptoms Radiographic evidence Microbiologic data We will also hear from a patient who details his diagnostic journey and will hear Dr. McShane discuss an illustrative clinical case. Presenter:  Pamela J. McShane, MD   Professor of Medicine  Division of Pulmonary...

In this episode, David Alain Wohl, MD, discusses key considerations to PrEP barriers in cisgender women, including: Prevalence of PrEP use in the US Barriers to PrEP uptake  PrEP efficacy based on adherence Interventions to support PrEP adherence Recommended PrEP regimens, including considerations for use in pregnancy and breastfeeding   Presenter:  David Alain Wohl, MD Professor of Medicine Schoo...

In this podcast, experts Sarah M. Wood, MD, MS, and Errol L. Fields, MD, PhD, MPH, discuss some of the challenges and concerns clinicians face when prescribing PrEP to adolescents.  The faculty addresses the potential for adverse effects from PrEP, including the potential for renal impairment, decreased bone density, and whether PrEP can interfere with hormone therapy for gender-affirming care. Th...

In this episode, we hear from 2 people living with HIV: Melanie Reese from the United States and Marc Thompson from the United Kingdom. Both Melanie and Marc have done important work in the HIV field as patient advocates. Today, they will be discussing their experiences in accessing and navigating their own HIV care, with a focus on some of the barriers that can complicate and even block a person'...

In this podcast, expert Rasika Karnik, MD, MS, discusses how to manage the health risks posed by COVID-19 infection and long COVID in individuals with metabolic syndrome or obesity. Dr Karnik discusses the interplay between COVID-19 outcomes, obesity/metabolic syndrome, and social determinants of health and delves into detail on how to address and mitigate these social determinants of health in a...

In this podcast, experts Donna Ryan, MD, and Renslow Sherer, MD, discuss how to manage the health risks posed by COVID-19 infection and long COVID in individuals with metabolic syndrome or obesity. First, Dr Ryan presents an overview of the relationship between COVID-19 and weight, including the mechanisms of how obesity may drive COVID-19 disease and how COVID-19 may in turn worsen obesity, throu...

In this episode, Oni Blackstock, MD, MHS, and Whitney Irie, MSW, PhD, discuss key considerations for PrEP uptake in cisgender women, including:  Ways to perform a nonintimidating sexual history  How to incorporate conversations on PrEP during a short clinic visit  Discussing adverse events associated with PrEP options with patients Considerations for PrEP in women wanting to conceive  How patients...

In this episode, Roger Bedimo, MD, MS, FACP, discusses key considerations to PrEP barriers in adolescents, including:  New HIV diagnoses in the United States Adherence barriers Healthcare professional barriers Consent laws for minors to receive sexually transmitted infection diagnosis and treatment services  Interventions to support PrEP adherence  Presenter:  Roger Bedimo, MD, MS, FACP Professor...

In this episode, Brooke Bates, PharmD, BCPS, AAHIVP, and Neha Sheth Pandit, PharmD, AAHIVP, BCPS, discuss the most clinically relevant studies on HIV adverse events presented at IAS 2023, including:  REPRIEVE study of pitavastatin for cardiovascular prevention in people living with HIV at low to moderate cardiovascular risk Data on weight change with switch from integrase inhibitor–based ART to do...

In this episode, Tony Brown, MPH, discusses the importance of effective patient‒provider communication in supporting PrEP persistence including:  His own experience with PrEP and reasons for fluctuations in adherence over the years  The importance of open, honest, and judgement-free conversations about sexual health  Engaging patients in conversations about PrEP effectiveness, adverse effects, and...

In this episode, Jill Blumenthal, MD, MAS, and Kenric B. Ware, PharmD, MBA, AAHIVP, answer questions about HIV PrEP including: Considerations for selecting between oral and injectable PrEP in college students Strategies to promote PrEP persistence in adolescents  Best approaches to address readiness to start PrEP in adolescents (eg, creating nonjudgmental environments, addressing misconceptions) C...

In this episode, Nikos Dedes, Jeff Taylor, and Bernadette Sharp—people living with HIV—discuss how switching to long-acting ART has affected their quality of life. They are joined by 2 healthcare professionals—Iskandar Azwa,MBChB, MRCP, and Beng Eu, MBBS—who provide insights on how they assess and document health-related quality of life for their patients. The discussion focuses on personal experi...

In this episode, Iskandar Azwa, MBChB, MRCP; Nikos Dedes; Beng Eu, MBBS; Bernadette Sharp; and Jeff Taylor discuss challenges and opportunities with long-acting ART implementation, including: Personal experiences with receiving LA ART  Views on long-acting ART in the development pipeline Perspectives on self-administration of LA ART Presenters: Iskandar Azwa, MBChB, MRCP Associate Professor Infect...

In this episode, Raphael J. Landovitz, MD, MSc, and Hyman Scott, MD, MPH, discuss key considerations for PrEP uptake in transgender individuals and racial and ethnic minority men who have sex with men, including:  Misconceptions about PrEP eligibility  Strategies to improve lab monitoring on PrEP  Leveraging patient navigators and clinic staff to expand PrEP access Data on PrEP efficacy in key pop...