Decera Clinical Education Infectious Disease Podcast

In this third of 3 episodes, global HIV experts and advocates discuss the current status of HIV cure research, including key concepts to understand and communicate when counselling patients, colleagues, and the broader community on HIV cure:  Latest understanding of the viral reservoir New insights and questions on the best timing for cure interventions Current investigational strategies showing p...

In this podcast, Julie Ann Justo, PharmD, MS, FIDSA, BCPS, discusses treatment of carbapenem-resistant Enterobacterales (CRE) infections, including: Burden of CRE infections in the United States Mechanisms of resistance Changing epidemiology Use of rapid diagnostic tests IDSA guidance recommendations, including supporting data Approach to designing treatment regimens, including weighing patient- a...

In this episode, Errol L. Fields, MD, PhD, MPH, and Armonté Butler, MPH, a pre-exposure prophylaxis (PrEP) advocate, discuss strategies for overcoming barriers to uptake of PrEP for HIV in adolescents and young adults, based on the unique needs of this patient population. Topics covered include: Methods for building trust between patients and providers Ways to practice shared decision-making and h...

During the 2023 American Association of the Study of Liver Diseases (AASLD) conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-delta agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate. In this episode, Stuart C. G...

During the 2023 American Association of the Study of Liver Diseases (AASLD) conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-delta agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate. In this episode, Marlyn J. M...

In this episode, Martin Rios discusses how pre-exposure prophylaxis (PrEP) persistence depends on healthcare professional knowledge, including: Their own experiences with the various PrEP providers they have seen The relief that has come with seeing PrEP providers who are supportive and knowledgeable about the different PrEP options The challenges that have come with seeing PrEP providers who are...

In this episode, Meredith Clement, MD, and Whitney C. Irie, MSW, PhD, discuss key considerations for pre-exposure prophylaxis (PrEP) uptake in cisgender women, including:  How to incorporate conversations on PrEP during a short clinic visit  Helpful resources about PrEP to share with patients Leveraging clinic staff to improve PrEP uptake and persistence  Available data on on-demand PrEP Approach...

In this episode, Helen Y. Chu, MD, MPH, shares updates on RSV seasonality, including:  Surveillance limitations due to the testing availability in adults Current 2023/2024 season trends, including predictions for other respiratory viruses (eg, influenza, SARS-CoV-2) Considerations for RSV administration RSV vaccine coadministration with influenza and COVID-19 vaccines Faculty:   Helen Y. Chu, MD,...

In this episode, Rick Zimmerman, MD, MPH, FAAFP, discusses RSV vaccines in older adults, including:  Breakthroughs in RSV vaccine development RSV vaccine snapshot in older adults FDA-approved RSV vaccines for older adults CDC evidence to recommendations framework for vaccines RSV burden in older populations Benefits and harms of RSV vaccination RSV vaccine efficacy and safety in older adults CDC A...

In this episode, Angela Branche, MD; Pamela Rockwell, DO, FAAFP; and Richard Zimmerman, MD, MPH, FAAFP, discuss the clinical presentation of RSV in older adults and available diagnostic tests for RSV, including:  Comparison of RSV clinical symptoms to influenza and COVID-19, including differentiating symptoms at infection onset RSV disease progression  RSV diagnostic approaches  How RSV diagnosis...

In this episode, Samantha V. Hill, MD, MPH, and Eunice E. Radcliff, MD, discuss key considerations for PrEP uptake in adolescents, including:  Advice on talking with parents about the importance of adolescents having alone time with their healthcare professionals Maintaining confidentiality when someone is on their parents’ insurance Strategies to increase awareness, uptake, engagement, and persis...

In this episode, Jean-Michel Molina, MD, PhD, discusses the data and recommendations for considering on-demand PrEP as a strategy to support PrEP persistence and engagement for men who have sex with men, including: Nondaily PrEP options recommended for cisgender men Data from the ANRS IPERGAY study evaluating on-demand FTC/TDF vs placebo in men who have sex with men Real-world data on the effectiv...

Should quantitative HBsAg testing be used routinely in clinical practice for patients living with chronic hepatitis B? In this episode, Tatyana Kushner, MD, MSCE, discusses the role of quantitative hepatitis B surface antigen testing in people living with chronic hepatitis B, including: Determination of inactive carrier status Prediction of liver fibrosis/cirrhosis Prediction of hepatocellular car...

Are we treating HBV early enough? Is it time to move the goalposts regarding the timing of treatment initiation? What are the potential benefits of earlier treatment? To answer these questions, Ira M. Jacobson, MD, leads a panel discussion with Tatyana Kushner, MD, MSCE, and Paul Y. Kwo, MD, exploring which patients with HBV we should be treating, including a focus on: Guideline-based treatment re...

In this episode, Angela Branche, MD; Pamela Rockwell, DO, FAAFP; and Rick Zimmerman, MD, MPH, FAAFP, discuss the burden of RSV in older adults, including: RSV burden throughout life RSV seasonality in the United States Comparative burden and incidence of RSV and influenza in adults aged 65 years or older Cardiopulmonary hospitalizations of long-term care facility residents with influenza and/or RS...

In this episode, Beatriz Grinsztejn, MD, PhD, discusses the data and recommendations for addressing social determinants as a strategy to support PrEP persistence and engagement for transgender women, including:  HIV prevalence among transgender women Data on the PrEP cascade from the PrEParadas study of daily FTC/TDF among transgender women Data from the ImPrEP Study on early loss to follow-up, ad...

In this accredited podcast episode, Dr Christina Madison and Dr Mary Bridgeman provide practical strategies for implementing RSV vaccination into practice, including:  Educating older adults on RSV vaccines Providing effective, evidence-based recommendations Shared decision-making Identifying and addressing vaccine hesitancy Proactive strategies in vaccinating for RSV Predicting and overcoming bar...

In this accredited podcast episode, Dr Christina Madison and Dr Mary Bridgeman discuss the latest practical strategies for preventing RSV infection in older adults, including:  Role of basic public health precautions Available and emerging vaccines  Mechanisms of action, therapeutic targets, and pharmacology Efficacy and safety data FDA approval status and ACIP recommendations  Presenters:   Mary...

In this accredited podcast episode, Dr Mary Bridgeman discusses the most important things for pharmacists across all settings to know about RSV infections in patients 60 years of age or older, including:  Incidence and prevalence of RSV in older adults, including hospitalization, mortality, epidemiology Seasonality Clinical manifestations Risk factors for severe outcomes Vulnerable groups and como...

In this episode, Aniruddha (Anu) Hazra, MD, and Ofole Mgbako, MD, discuss key considerations for PrEP uptake in transgender individuals and racial and ethnic minority men who have sex with men, including:  Data on drug–drug interactions between PrEP options and gender-affirming hormone therapy Contributing factors to inequities in PrEP uptake for Black and Latino individuals Data on FTC/TAF PrEP f...

In this episode,Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections caused by NDM-producing Enterobacterales, including:  Ambler classification of β-lactamases Mechanisms of resistance 2023 IDSA guidance recommendations The latest clinical data by antimicrobial regimen: Ceftazidime/avibactam and az...

In this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections involving Pseudomonas aeruginosa with difficult-to-treat resistance, including:  Mechanisms of β-lactam resistance Effect of resistance mechanism on susceptibility to antipseudomonal agent 2023 IDSA guidance recommendations  Activ...

In this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections involving carbapenem-resistant Acinetobacter baumannii  (CRAB), including:  Mechanisms for β-lactam resistance Additional resistance mechanisms and virulence factors 2023 IDSA guidance recommendations for moderate to severe CRAB i...

In this second of 3 episodes, global HIV experts and advocates discuss how HIV care can better meet the diverse needs of people living with HIV as new treatment strategies emerge and continue to evolve, including: How the emergence of long-acting injectable HIV treatment has been a game-changer for many people living with HIV Emerging strategies that are expanding the application of long-acting AR...

In this episode, global PrEP experts and advocates discuss how current PrEP regimens represent a revolutionary step forward in enabling many individuals to avoid HIV acquisition, including:  How PrEP has empowered people to take control of their sexual lives, revolutionized people’s sexual experiences, and, for some, improved their experiences with healthcare in general The extraordinary progress...