Core IM | Internal Medicine Podcast

Next time you’re squinting at a chest tube, feel confident you know exactly what to look for and why. Hear it explained in a way that really sticks! 🔹  Sponsor : Oakstone CME’s ACP MKSAP Audio Companion Use the code "CORE30" for 30% off effective 11/1/25 through 1/31/26:  https://www.coreimpodcast.com/MKSAP 🔹  Transcript & Show Notes Timestamps: (02:50) | Xray vs. POCUS vs. CT for Pn...

How do you work up neutropenia? When is neutropenia benign? When do neutrophils recover? How can you diagnose neutropenic fever in the first 15 minutes and start antibiotics in the first 60 minutes? Do you always add MRSA coverages? Only Pseudomonas coverage? When do you add fungal coverage? 🔹 Sponsor : Oakstone CME’s ACP MKSAP Audio Companion Use the code "CORE30" for 30% off effective 1...

Have a good laugh and reflect deeply with these three stories that hit the feels in different ways. If you'd love to hear more stories from Dr. Maria Rosasco, check out some of her other appearances on the podcast: July Stories and Handoffs & Contingency Planning . 🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion Use the code "CORE30" for 30% off effective 11/1/25 through 1/31/...

What went wrong? What were the reasoning or contextual missteps that led us astray? 🔹  Sponsor :  NEJM Fellowship Program, click  here to learn more and/or apply ! Due Aug 1, 2025 🔹 Transcript and Show Notes Timestamps: (00:02) | Case Presentation and Initial Diagnosis (02:47) | Tachycardia and Early Impressions (04:10) | Clinical Deterioration and New Clues (07:19) | Problem Representation and...

Imaging Pearls | (01:12) Deciding on Thoracentesis | (04:00) Light’s Criteria and Pseudoexudates | (07:00) Pleural Fluid Studies: pH and Cell Differential | (16:56) Diagnosing and Treating Parapneumonic Effusions | (23:32) Malignant Pleural Effusions: Diagnosis and Management | (30:39) 🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion Use the code "CORE30" for 30% off effective 11/1/25...

Listen for some good laughs and relatable stories! In this episode, we share raw and real stories from July — from rapid responses to unexpected kindness — and reflect on the emotional weight of starting out in medicine. 🔹 Sponsor :  NEJM Fellowship Program, click  here to learn more and/or apply ! Due Aug 1, 2025 🔹 Transcript and Show Notes Prior July Stories : July Stories 2.0 (2023) July Stor...

How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care , examine how evidence evolved, and explore the REDUCE-AMI trial , which questions whether beta blockers are still needed for all. Listen to this latest episode of Beyond Journal Club , a collaboration between Core IM and NEJM Group, wher...

🔹 What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? (~ 02:46) 🔹 What are the main classes of fungi? (~11:35) 🔹 What are the pros and cons of B-D Glucan and Galactomannan (~19:16) 🔹 How to increase the yield of blood cultures? How to interpret yeast growth in sputum/BAL and urine cultures? (~ 30:42) 🔹 How is invasive fungal disease treated? (~ 35:...

🔹What are clinically relevant limitations of an A1c vs. a CGM (1:40) 🔹What do the different parts of the ambulatory glucose profile tell you? (09:59) 🔹What are common pitfalls, medications, lifestyle patterns that are important to ask your patient about when seeing them for a visit to manage blood sugar? (15:19) 🔹 How can you titrate insulin based on when you see the hypoglycemia on the ambula...

🔹When is an U/S vs. CT vs. MRI helpful before consulting Interventional Radiology? 🔹What factors go into an IR pre-op evaluation? 🔹 When do drains go in, and when do they come out? 🔹 When a patient has trouble with a drain, what are things you can do before calling IR? 🔹 What does outpatient IR follow up entail, and what does a capping trial of PCN tubes entail? 📌   Sponsor : Oakstone CME’s...

🔹 High-yield reversible causes of constipation? (02:26) 🔹 Which type of fiber is more helpful? And is more hydration really better? And bulk-forming laxatives (9:03) 🔹 Osmotic vs Stimulant Laxatives (15:06) 🔹 Suppositories and enemas? (25:39) 🔹Best practices with opioid induced constipation (34:05) 📌   Sponsor :  Freed  is an AI scribe that listens and writes your note in < 30 seconds. Fr...

How good are we at preventing HIV? How do efficacy and effectiveness differ? We journey from oral pre-exposure prophylaxis (PrEP) to long-acting injectables , and then to the PURPOSE trials , which look at the use of long-acting lenacapavir as PrEP — a potential game-changer in the field of HIV . Listen to this latest episode of Beyond Journal Club , a collaboration between CoreIM and NEJM Group ,...

What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a). Learn how to interpret results, counsel patients, and navigate topics with limited data like aspirin and PCSK9 inhibitors in treatment. 🔹 Sponsor :  Freed  is an AI scribe that listens and writes yo...

A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the nuances and practical approaches!  🔹 Sponsor :  Freed  is an AI scribe that listens and writes your note in < 30 seconds. Freed  learns your style  over time and is HIPAA compliant!  Use the code...

What is the impact of microplastics on human health? How can we use observational data to support the argument that microplastics may lead to poor health outcomes? Join us as we tackle these questions and discuss the APAChE study on microplastics and cardiovascular disease on   this episode of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group. 🔹 Transcript a...

What is the last sense to go? How can music create connection, ease anxiety, and help process emotions at the end of life? Join Dr. Jafar Al-Mondhiry, Dr. Harry Han, and music therapist Bryanna Tobin as they explore the power of music therapy in hospice care, sharing moving stories and clinical insights. 🔹  This episode is also sponsored by Factor!  Get fresh, ready-made meals delivered to your d...

Incidental fibrosis on CT —what now? What does prone imaging tell you? Is it fibrosis, aspiration, or atelectasis? And once you diagnose ILD, does the “alphabet soup” really matter for treatment? Antifibrotics vs. immunosuppression? Plus, how do we bridge the gap when social barriers make care unsafe? 🔹 This episode is also sponsored by Factor! Get fresh, ready-made meals delivered to your door....

SPEP vs. UPEP? What does it tell you and not tell you? What is the role for immunofixation and free light chains in diagnosis? Learn about paraneoplastic antibodies with MGCS and its renal, neurologic, and dermatologic manifestations! Sponsor :  Freed  is an AI scribe that listens and writes your note in < 30 seconds. Freed  learns your style  over time and is HIPAA compliant!  Use the code  CO...

How do you differentiate immune checkpoint inhibitor-related adverse events aka IrAEs from other conditions like infection? Join as we go through pneumonitis, colitis, dermatitis and endocrinopathies due to immune checkpoint inhibitor toxicity! Transcript and Show Notes ICIs & IrAEs 101 Episode Behind The Scenes video  Sponsor: Interested in integrating Glass AI into your EMR? Reach out to en...

YouTube Videos Anion Gap Metabolic Acidosis:  https://youtu.be/oE0lygmMANM Inhaler Delivery Systems:  https://youtu.be/yYPdjClm9Bg Iron Deficiency in Pregnancy  https://youtu.be/xTzYSXUbLsc Subscribe to  Core IM’s YouTube Channel  for more behind the scenes, whiteboard animations and more! Timestamps: 01:27 | Anion Gap Metabolic Acidosis (Dr. Nick Villano) 02:52 | Inhaler Delivery Systems (Dr. All...

What’s the evidence been for the use of PPIs in mechanically ventilated patients? What do more recent studies reveal about PPIs and possible harmful side effects of aspiration pneumonia and C. difficile colitis? To find out, tune into the second season of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group. Sponsor :  Freed  is an AI scribe that listens and wri...

Why are we missing peripheral arterial disease (PAD)? How is it diagnosed using the Ankle-Brachial Index (ABI)? What treatments improve symptoms and reduce cardiovascular risks? When should revascularization be considered? Transcript and Show notes Behind The Scenes YouTube Interview Subscribe to  Core IM’s YouTube Channel  for more behind the scenes, whiteboard animations and more! Timestamps: (...

How is TPN and PPN similar and how is it different? When should each be used? How does bacterial overgrowth lead to complications? Does TPN cause diarrhea? Transcript and Show notes Behind the Scenes Youtube Interview Subscribe to  Core IM’s YouTube Channel  for more behind the scenes, whiteboard animations and more! Timestamps: (01:35) |  PEARL 1:  Basics of PN: What makes up parenteral nutritio...

Limitations to urine drug screening (UDS) in primary care? What are common false positives and false negatives with the urine drug screen test?  Transcript and Show notes Behind The Scenes YouTube Interviews  Subscribe to  Core IM’s YouTube Channel  for more behind the scenes, whiteboard animations and more! Timestamps: (03:01) | PEARL 1: Basics to Urine Drug Screen (UDS) (08:03) | PEARL 2: Type...

What if a patient can't afford hospice? Which medications do you deprescribe when on hospice? What happens when patients who are on hospice return to the hospital or ED? Sponsor : Imagine leveraging A.I to do pre-charting before seeing a patient. Reach out to  enterprise@glass.health  to integrate Glass A.I into your EMR! For more on  Glass or Glass Pro , Use the promo code: CoreIM Behind the...