Cleveland Clinic Cancer Advances

The Cancer Advances podcast is joined by colorectal surgeons, I. Emre Gorgun, MD, Vice Chair of the Department of Colorectal Surgery, and Joshua Sommovilla, MD, Director of the Colon Cancer Tumor Board, to talk about organ preservation in rectal cancer treatment. Listen as they discuss the rising use of neoadjuvant therapy to shrink tumors before surgery, endoluminal procedures, and the importance...

Shilpa Gupta, MD, Director of the Genitourinary Oncology Program at Cleveland Clinic Cancer Institute, provides an overview of the clinical trial of enfortumab vedotin and pembrolizumab in untreated advanced urothelial cancer. Listen as Dr. Gupta talks about the exciting results of the trial, which showed that the combination therapy was effective for both cisplatin-eligible and cisplatin-ineligib...

Anjali Advani, MD, Director of the Inpatient Leukemia Unit at Cleveland Clinic, joins the Cancer Advances Podcast to talk about the innovations in acute lymphoblastic leukemia (ALL). While chemotherapy has traditionally been the go-to treatment, advancements like blinatumomab and CAR-T cell therapy are reshaping care. Listen as Dr. Advani discusses the challenges and considerations in choosing the...

Halle Moore, MD, Director of Breast Medical Oncology at Cleveland Clinic, joins the Cancer Advances Podcast to explore the safety of pregnancy after breast cancer with BRCA mutations. In the episode, Dr. Moore emphasizes the importance of early conversations regarding reproductive goals and available fertility preservation strategies for breast cancer patients while maintaining an effective cancer...

Hematology oncologist, Allison Winter, MD, joins the Cancer Advances podcast to discuss the latest innovations in treating chronic lymphocytic leukemia (CLL). Listen as she explains how the treatment for CLL has evolved over the past decade, with a shift towards using novel therapies such as BTK inhibitors and venetoclax, as well as the concept of time-limited therapy. Dr. Winter also shares insig...

Alison Ibsen, Senior Director for Cancer Programming, joins the Cancer Advances Podcast to talk about the role of cancer programming to enhance cancer patient care. Cancer programming brings together various experts involved in the treatment of a specific cancer to promote multidisciplinary care to help improve outcomes. Listen as Alison elaborates on the program development, its emphasis on creat...

Michael Valente, DO, Program Director for the Colorectal Surgery Residency Program, and Director of the Peritoneal Surface Malignancy Program & Center for Metastatic Colorectal Cancer at Cleveland Clinic, joins the Cancer Advances Podcast to discuss advances in stage 4 colon cancer treatment. Listen as Dr. Valente highlights the significant improvements in outcomes for late stage colon cancer...

The Cancer Advances podcast is joined by surgeon, Federico Aucejo, MD, Director of the Liver Tumor Clinic, and medical GI oncologist, Bassam Estfan, MD, Co-Director of the Liver Tumor Program, to discuss the use of ctDNA screening in colorectal cancer with liver metastases. Tune in to learn about the current state of disease management and the potential of ctDNA testing to guide treatment decision...

Michelle Kuznicki, MD, a gynecologic oncologist, joins the Cancer Advances podcast to talk about fertility-sparing surgery for early-stage cervical cancer. Drawing from her systematic review of oncologic and pregnancy outcomes associated with various surgical techniques, Dr. Kuznicki talks about the shift towards less invasive procedures, highlighting the importance of aligning surgical options wi...

Hematologist, Shahzad Raza, MD, joins the Cancer Advances Podcast to talk about the evolving understanding of smoldering multiple myeloma. Listen as Dr. Raza discusses the challenges in risk stratification, complexities of treatment decisions, and the need for close patient monitoring and education.

The Cancer Advances podcast is joined by Dr. Eileen Slavin, DO, a physiatrist specializing in oncology rehabilitation, to discuss the important role of oncology rehabilitation services in cancer recovery. Listen as Dr. Slavin explains the significance of prehabilitation, collaboration with physical therapy and palliative care, and how the field is evolving.

Brian T. Hill, MD, PhD, Co-Director of the Lymphoid Malignancies Program at Cleveland Clinic, joins the Cancer Advances Podcast to discuss advances in mantle cell lymphoma. Listen as Dr. Hill highlights current treatments and how promising strategies like BTK inhibitors and CAR T-cell therapy are being used. He also addresses challenges such as TP-53 mutations, discusses potential advancements, an...

Mailey Wilks, CNP, APP manager at the Taussig Cancer Center, and Heather Koniarczyk, CNP, Director of Advanced Practice, join the Cancer Advances Podcast to discuss the implementation and success of a Virtual Anemia Clinic. The clinic was developed to address the increased demand for anemia consult requests and aim to reduce average wait times. Listen as they explain how the virtual platform allow...

Associate Director of the Gamma Knife Center at Cleveland Clinic, Samuel Chao, MD, joins the Cancer Advances Podcast to talk about the evolution of gamma knife technology. Listen as Dr. Chao takes us through gamma knife's history, the current advantages and considerations, as well as potential future advances in the field.

Shauna Campbell, DO, Radiation Oncologist and Co-Director of the Cleveland Clinic Sarcoma Program joins the Cancer Advances podcast to discuss ultra-hypofractionated radiotherapy for soft tissue sarcoma. Listen as Dr. Campbell explains the advancements, outcomes, and considerations of this innovative approach, referencing her meta-analysis that was presented at the American Society of Radiation On...

Peter Mazzone, MD, MPH, pulmonologist and Section Leader for Thoracic Oncology at Cleveland Clinic, joins the Cancer Advances podcast to discuss the development of blood tests to screen for lung cancer. Listen as Dr. Mazzone explains the intricacies of DNA analysis within these tests, offering insights into their potential to detect lung cancer and alleviate barriers to screenings.

Sudha Amarnath, MD, Co-Director of the Gynecologic Cancer Program, joins the Cancer Advances podcast during Cervical Cancer Awareness Month to share insights on how to improve the quality of care for cervical cancer patients. Listen as Dr. Amarnath talks about the metrics considered for improvement, including tumor board presentations, pathology reviews, imaging protocols, and socioeconomic suppor...

Laura Shoemaker, DO, Chair of Palliative and Supportive Care at Cleveland Clinic, joins the Cancer Advances podcast to discuss navigating difficult conversations in the field of oncology. Listen as Dr. Shoemaker shares valuable insights into the essential elements for handling hard discussions, including empathy, validating emotions, and the importance of fostering a relationship built on trust.

Section Chief of Reproductive Endocrinology and Infertility at Cleveland Clinic's Fertility Center, Mindy Christianson, MD, MBA, joins the Cancer Advances podcast to discuss uterine-focused fertility preservation. Dr. Christianson talks about the uterine damage that can be caused by pelvic radiation and explains uterine transposition as a solution. During the episode, Dr. Christianson provide...

Jacob Miller, MD, a Radiation Oncologist at Cleveland Clinic, joins the Cancer Advances podcast to share his insights on nasopharyngeal carcinoma (NPC) screening and his trial presented at the American Society of Radiation Oncology (ASTRO) 2023 Annual Meeting. NPC is rare in the United States but prevalent in Southern China, primarily caused by the Epstein-Barr virus (EBV). Listen as Dr. Miller ex...

The Cancer Advances podcast is joined by Shahzad Raza, MD, a hematologist at Cleveland Clinic Cancer Center, discussing eye toxicities linked to cancer treatments. Listen as Dr. Raza talks about his study examining real-world experiences compiling eye toxicities from several anticancer drugs. During the podcast, he emphasizes the importance of the early involvement of ophthalmologists in patient c...

Emre Gorgun, MD, colorectal surgeon and Vice Chair of Colorectal Surgery at Cleveland Clinic, joins the Cancer Advances podcast to talk about his study from Digestive Disease Week (DDW) on predicting complete responses to total neoadjuvant therapy (TNT) in patients with locally advanced rectal cancer. Listen as Dr. Gorgun share insights on success rates of TNT, the factors influencing complete res...

Faiz Anwer, MD, a hematologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss CRISPR, a gene-editing technology. Listen as Dr. Anwer highlights CRISPR's advantages over traditional cellular therapies, the challenges of off-target effects, and its future in solid tumor treatment.

Medical Oncologist and Co-Director of the Lung Cancer Program at Cleveland Clinic, Nathan A. Pennell, MD, PhD joins the Cancer Advances podcast to discuss the study he and his team conducted exploring the potential benefits of transitioning from single-gene testing to next-generation sequencing (NGS). Listen as Dr. Pennell explains the pivotal role genomic testing has in treating lung cancer and t...

Radiation Oncologist and Co-Director of the Comprehensive Breast Cancer Program at Cleveland Clinic, Chirag Shah, MD, joins the Cancer Advances podcast to discuss his study on the innovative use of CPAP (Continuous Positive Airway Pressure) machines in combination with radiation therapy. Listen as Dr. Shah explains how using CPAP machines in radiation therapy has been shown to reduce radiation-rel...