Cleveland Clinic Cancer Advances

Jamie Ku, MD, Director of the Head and Neck Robotic Surgery Program at Cleveland Clinic joins the Cancer Advances Podcast to discuss the newly released ASCO clinical practice guidelines for transoral robotic surgery (TORS) in patients with HPV-positive oropharyngeal cancer. Listen as Dr. Ku, who co-chaired the ASCO expert panel, provides insight into the multidisciplinary process behind the guidel...

Matteo Trucco, MD, Director of the Children’s Cancer Innovative Therapy Program, joins the Cancer Advances Podcast to discuss the Cleveland Clinic Children's recent recognition as the first center in the nation to receive pediatric cancer subcommittee accreditation from the Commission on Cancer. Learn how this milestone is not only advancing pediatric cancer care at Cleveland Clinic but also...

Chair of the Department of Gastroenterology, Hepatology and Nutrition, Michelle Kang Kim, MD, PhD, joins the Cancer Advances podcast to discuss her team’s innovative work using electronic health records (EHR) to develop a predictive model for noncardiac gastric cancer. Listen as Dr. Kim explains how the model uses common clinical variables to flag high-risk patients who may benefit from endoscopic...

Brian T. Hill, MD, PhD, Director of the Lymphoid Malignancies Program at Cleveland Clinic, joins the Cancer Advances Podcast to talk about the latest updates in first-line therapy for chronic lymphocytic leukemia (CLL). During this episode, Dr. Hill explains the shift from traditional chemoimmunotherapy to more precise, targeted treatments, and how customized therapy is transforming patient outcom...

The Cancer Advances Podcast welcomes back Abhay Singh, MD, MPH, Director of the CHIP Clinic at Cleveland Clinic, to explore the evolving landscape of survivorship care. Listen as Dr. Singh provides insights on how personalized, patient-centered approaches are being integrated with shared care models to address late effects, psychological challenges, and the needs of a growing population of cancer...

Abhay Singh, MD, MPH, Director of the CHIP Clinic at Cleveland Clinic, joins the Cancer Advances Podcast to discuss a major new study exploring the link between GLP-1 receptor agonists and the risk of hematologic malignancies in patients with diabetes. Tune in to hear how GLP-1s, best known for managing diabetes and obesity, may hold promise for cancer prevention and what this could mean for futur...

The Cancer Advances Podcast is joined by the Chair of the Division of Pediatric Hematology Oncology and Director of the Bone Marrow Transplant Program, Rabi Hanna, MD, along with Ilia Butoriarov, MD, a physician at the Division of Pediatric Hematology Oncology leading the Leukemia Lymphoma Program to discuss evolving approaches to treating pediatric Hodgkin lymphoma. Listen as they talk about how...

Alok Khorana, MD, Director of the Gastrointestinal Malignancies Program at Cleveland Clinic Cancer Institute, joins the Cancer Advances Podcast to break down the latest research on early-onset biliary tract cancer, diving into the genetic and molecular differences that set it apart. Listen as Dr. Khorana addresses the challenges in diagnosing and treating this cancer and the exciting potential for...

Michael Fritz, MD, Director of the Section of Facial Plastic and Reconstructive Surgery at Cleveland Clinic, joins the Cancer Advances Podcast to talk about the approaches to the classification and management of mandibular osteoradionecrosis (ORN). Listen as Dr. Fritz shares insights into the classification and treatment of ORN, including the role of PENTO therapy and the groundbreaking anterolate...

The Cancer Advances podcast is joined by hematologists Sandra Mazzoni, DO and Shahzad Raza, MD to discuss the latest advancements in multiple myeloma treatment. Listen as they explore the evolving role of CAR-T cell therapy, bispecific antibodies, and autologous stem cell transplants and how they are changing the multiple myeloma treatment landscape.

Kevin Elias, MD, the Lilli and Seth Harris Endowed Chair for Ovarian Cancer at Cleveland Clinic, joins the Cancer Advances podcast to discuss the challenges of trying to detect ovarian cancer early and the need for better predictive tools. Listen as Dr. Elias talks about the MiDe Study, which aims to identify high-risk women through microRNA-based blood tests, potentially transforming ovarian canc...

Gloria Gonzalez, MD, Pediatric Surgeon and Director of Pediatric Surgical Oncology, joins the Cancer Advances podcast to provide her insights on advanced surgical techniques for neuroblastoma. Listen as Dr. Gonzalez explains the complexities of neuroblastoma, the use of 3D printing in preoperative planning and 3D image-guided surgery, and the emerging role of fluorescent-guided surgery.

The Cancer Advances podcast is joined by the Chair of the Palliative and Supportive Care Department, Laura Shoemaker, DO, and Integrative Medicine Specialist, Naoki Umeda, MD, to talk about Cleveland Clinic’s Integrative Oncology Program. Listen as they share how combining evidence-based complementary therapies, such as acupuncture and lifestyle medicine, with conventional cancer treatment can hel...

Paolo Caimi, MD, Associate BMT Director for Cell Therapy at Cleveland Clinic Cancer Institute, joins the Cancer Advances podcast to discuss the latest advancements in immunotherapy for aggressive lymphomas. Listen as Dr. Caimi talks about the potential of bispecific antibody combinations, including early-phase findings on glofitamab plus ICE chemotherapy for relapsed and refractory diffuse large B...

Vice Chair of the Center for Immunotherapy & Precision Immuno-Oncology, J. Joseph Melenhorst, PhD, joins the Cancer Advances Podcast to discuss the potential of CAR T-cell therapy for chronic lymphocytic leukemia (CLL). Listen as Dr. Melenhorst explains how advancements in cell therapy are overcoming challenges like T cell exhaustion, improving response rates, and how novel approaches could im...

Moshe Ornstein, MD, MA, a Genitourinary Medical Oncologist joins the Cancer Advances podcast to talk about intermittent therapy for metastatic renal cell carcinoma (mRCC). Listen as Dr. Ornstein explores the evolution of treatment options, from cytokine and targeted therapies to immunotherapy, and as he delves into the promising concept of treatment breaks to improve patient outcomes.

Medical Oncologist in the Lymphoid Malignancies Division, Taylor Brooks, MD, joins the Cancer Advances podcast to discuss real-world data on bispecific antibodies for relapsed or refractory large B-cell lymphomas that was presented at the 2024 American Society of Hematology (ASH) Annual Meeting. Listen as Dr. Brooks shares insights into efficacy, safety, and challenges patients face outside clinic...

Lukas Nystrom, MD, Orthopaedic Oncology Surgeon and a Co-Director of the Sarcoma Program at Cleveland Clinic joins the Cancer Advances Podcast to talk about the advancements in custom 3D-printed implants for pelvic sarcoma reconstruction. Listen as Dr. Nystrom explains how these personalized implants are transforming sarcoma care by enhancing precision during tumor resections, offering tailored so...

Ruth Keri, PhD, Associate Director for Basic Research at Case Comprehensive Cancer Center and Professor of Cancer Biology at Cleveland Clinic, returns to the Cancer Advances Podcast to share the latest advancements in targeting YES1 protein to treat triple-negative breast cancer (TNBC). Listen as Dr. Keri discusses how YES1 impacts chemotherapy resistance, tumor growth, and EGFR inhibition, uncove...

The Cancer Advances podcast is joined by Director of Pediatric Radiation Oncology, Erin Murphy, MD, and resident physician, Jenna Kocsis, MD, to share their latest findings on the use of stereotactic body radiation therapy (SBRT) to treat recurrent osteosarcoma. Listen as they discuss the challenges of managing this radio-resistant tumor, including its use in complex cases involving the spine and...

Theresa Callard-Moore, PhD, LSW, a psychotherapist and certified sex therapist at Cleveland Clinic, joins the Cancer Advances podcast to shed light on the often-overlooked topic of sexual health in cancer patients. In this episode, Dr. Callard-Moore emphasizes the importance of initiating open conversations about sexual health early in the care journey. She also shares valuable insights, practical...

Ali Azka, MD, medical oncologist specializing in breast cancer joins the Cancer Advances podcast to talk about her new research on ESR1 mutations and the PI3-kinase pathway's impact on the effectiveness of elacestrant in treating advanced hormone receptor-positive, HER2-negative breast cancer. This study, presented at the 2024 San Antonio Breast Cancer Symposium (SABCS), highlights the role o...

Chair of the Department of Colorectal Surgery, Director of the Weiss Center for Hereditary GI Neoplasia and Center for Young Onset Colorectal Cancer, David Liska, MD, joins the Cancer Advances Podcast to discuss Cleveland Clinic's integrated program for young people with cancer. Listen as Dr. Liska explains the rise in early-onset cancers, potential factors, and the unique challenges young pa...

Beth Faiman, PhD, CNP, a Nurse Practitioner and Clinical Researcher at Cleveland Clinic specializing in multiple myeloma, joins the Cancer Advances podcast to discuss updates in managing relapsed and refractory multiple myeloma. Listen as Dr. Faiman talks about advancements in treatment, including proteasome inhibitors, monoclonal antibodies, and bispecific antibodies, which improve both survival...

Michael Kelly, MD, PhD, a pediatric hematologist and oncologist at Cleveland Clinic Children's, joins the Cancer Advances podcast to discuss innovative care for vascular anomalies. In this episode, Dr. Kelly explains how they are exploring advanced treatments, including clinical trials using cancer medications to address these non-cancerous conditions, the impact of somatic mutations, and the...