Cardio Deep Dive

Coronary artery disease (CAD) is a complex condition resulting from the interplay of behavioral, environmental, and genetic factors. While modifiable risk factors like smoking and hypertension are well-recognized, recent large-scale genomic studies have identified hundreds of genetic variants that significantly influence susceptibility. This inherited basis manifests in two primary forms: rare mon...

This podcast examines the unique  biological resilience  of the  internal mammary artery (IMA) , which remains remarkably  resistant to atherosclerosis  despite being exposed to the same systemic risks as other vessels. While traditional risk factors drive disease in most arteries, the IMA possesses specialized  endothelial properties , including high  nitric oxide production  and a robust  intern...

Welcome to Cardio Deep Dive latest episode. In today’s episode we focus on vulnerable plaque : the high-risk atherosclerotic lesion characterized by a thin fibrous cap, large lipid core and intense inflammation that predisposes to rupture, thrombosis, and acute coronary syndromes despite often minimal stenosis. We’ll explore its pathophysiology, clinical significance, and evolving imaging and mana...

Drug Coated Balloons have emerged as a novel strategy in the treatment of coronary artery disease. However there are lots of challenges and myths surrounding their use. This podcast is an effort to unravel the science behind their efficacy, indications and scenarios of their use, and the correct methodology required for safe implantation of DCB.

Intra vascular Imaging tools like Optical Coherence Tomography (OCT) and Intra Vascular Ultrasound (IVUS) are an indispensable tool to optimise coronary interventions. Recently they have become Class I an indication for complex PCI. This podcast is an effort to describe the role of OCT and IVUS in contemporary interventional practice.

Lipoprotein(a), is a hidden and often overlooked cholesterol particle that significantly increases the risk of heart attacks, strokes, and aortic valve disease—even in people with “normal” cholesterol levels. In this episode, we break down what Lp(a) is, why it’s largely genetic, who should get tested, and what current and emerging treatments can (and cannot) do. A must-listen for patients, famili...