Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals

Stanley Hazen, MD, PhD, and Scott Cameron, MD, PhD, discuss emerging evidence linking gut microbiome-derived TMAO to abdominal aortic aneurysm development and progression. They explore its role as both a causative factor and a biomarker, review current risk stratification strategies and highlight future therapeutic approaches aimed at reducing TMAO levels to improve vascular outcomes. Learn more a...

Hani Najm, MD, and Joanna Ghobrial, MD, discuss the evolving role of transcatheter pulmonary valve implantation in lifetime management of congenital heart disease patients. They explore patient selection, valve durability, imaging strategies for early detection of HALT or HAM and the collaborative heart team approach that optimizes outcomes. Looking to refer a patient? Please reach out to our Phys...

Venugopal Menon, MD, Director of the Coronary ICU, and Michael Tong, MD, cardiothoracic surgeon specializing in advanced heart failure, discuss contemporary management of post-infarction ventricular septal rupture, a rare but serious complication. They review the role of early transfer to high-volume centers and why definitive surgical closure remains the gold standard. Learn about the impact of t...

Kenneth McCurry, MD, and Marie Budev, DO, share Cleveland Clinic’s multidisciplinary approach to managing end-stage lung disease and advancing lung transplantation. They discuss innovations such as ex vivo lung perfusion (EVLP), ECMO bridging, and strategies for expanding donor and recipient criteria, including complex and multi-organ cases. The episode also highlights ongoing research and clinica...

Samir Kapadia, MD, Chairman of Cardiovascular Medicine at Cleveland Clinic, and David Zidar, MD, PhD, an interventional cardiologist and immunologist, introduce Cleveland Clinic’s Cardioimmunology Center, a new initiative focused on the intersection of immune pathways and cardiovascular disease. They discuss how immune system activity can influence heart health and discuss innovative approaches to...

Lee Kirksey, MD, Aravinda Nanjundappa, MBBS, MD, and G. Jay Bishop, MD, discuss a multidisciplinary approach to peripheral artery disease (PAD) management. They explore evidence-based strategies including early detection, optimal medical therapy, supervised exercise programs and advanced endovascular and surgical interventions, emphasizing team-based care and longitudinal follow-up for improved ou...

Allan Klein, MD, and Tom Kai Ming Wang, MBChB, discuss the 2025 ACC Concise Clinical Guidance on pericardial disease. They explore updated diagnostic criteria, the role of multimodality imaging and a shift toward IL-1 blockers for recurrent pericarditis. Learn practical strategies to optimize patient outcomes and avoid misdiagnosis or undertreatment, along with insights on surgical options and eme...

Lars Svensson, MD, PhD, and Xiaoying Lou, MD, share a deep dive into valve-sparing aortic root surgery, an advanced technique that preserves the patient’s native valve while treating aortic aneurysms. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Steven Nissen, MD, and Luke Laffin, MD, discuss a groundbreaking phase 1 trial of a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3. They explore its potential as a one-time treatment to significantly lower LDL cholesterol and triglycerides, with promising safety and efficacy data that could reshape lipid management. Learn more about C5 Research at Cleveland Clinic. https://my.clevelandclinic.o...

A. Marc Gillinov, MD, and Tarek Malas, MD, discuss the long-term benefits of mitral valve repair for patients with degenerative mitral valve disease. They explore surgical decision-making, robotic techniques and post-operative recovery strategies like cardiac rehab that support lifelong valve function and optimal patient outcomes.  Looking to refer a patient? Please reach out to our Physician Refe...

Kenneth McCurry, MD, and Marie M. Budev, DO, discuss Cleveland Clinic’s leadership in lung and multi-organ transplantation, highlighting innovations like ex vivo lung perfusion (EVLP) and the collaborative care model that supports complex transplant cases. They also acknowledge Lung Transplant Awareness Day, a national initiative aimed at increasing education about end-stage lung disease. Looking...

Tamanna Singh, MD, and Amanda Vest, MBBS, discuss the relationship between obesity and heart failure. They discuss multidisciplinary strategies, including lifestyle interventions and pharmacologic therapies like GLP-1 receptor agonists for managing patients across the spectrum of heart failure. Learn emerging clinical research regarding obesity and heart failure from Cleveland Clinic experts.  Loo...

Donna Kimmaliardjuk, MD, and Faisal Bakaeen, MD, explore the latest in multi-arterial coronary artery bypass grafting (CABG). They discuss patient selection, surgical techniques and long-term outcomes supported by optimal medical therapy.  Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

When a heart is weak after a heart attack, cardiac arrest or surgery, mechanical circulatory support (MCS) can help the heart function while it heals or assist patients long-term.  Cleveland Clinic experts discuss MCS devices, specifically the Impella percutaneous left ventricular assist device (LVAD) and extracorporeal membrane oxygenation (ECMO). Looking to refer a patient? Please reach out to o...

Amanda Vest, MBBS, explores sex-based differences in heart failure, focusing on biological and social factors that influence disease development, treatment response and outcomes in women. She highlights disparities in risk factors, access to care and clinical trial representation that can influence heart failure outcomes.  Looking to refer a patient? Please reach out to our Physician Referral team...

Scott Cameron, MD, highlights the underdiagnosis and undertreatment of peripheral artery disease (PAD) in women. He discusses diagnostic challenges and emphasizes the  need for improved screening, female-specific guidelines and more inclusive research to address disparities in care. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855...

Women are more likely than men to experience atrial fibrillation symptoms. Mohamed Kanj, MD, discusses gender-based differences in atrial fibrillation treatment, including rate control, rhythm control and anticoagulation.  Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Ravi Ambani, MD, and Aravinda Nanjundappa, MBBS, MD, discuss Cleveland Clinic’s leadership and progress in treating carotid artery disease. Learn how multidisciplinary teams are transforming care with new research on medical and surgical therapies.  Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Chronic thromboembolic pulmonary hypertension (CTEPH) is a type of pulmonary hypertension caused by chronic blood clots in the lungs. It is an under-recognized condition, but with accurate imaging and quality treatment, it can often be cured. Gustavo Heresi, MD, and Michael Tong, MD, discuss diagnosis, medical therapy and surgical options for people with CTEPH. Looking to refer a patient? Please r...

When treating mitral valve disease, a surgeon must decide whether to repair or replace a valve. Cleveland Clinic experts discuss robotically-assisted surgery, reoperations and the outcomes a patient can expect from surgery at Cleveland Clinic. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469. Meet the presenters: Marc Gil...

Connective tissue disorders like Marfan, Loeys-Dietz, and Ehlers-Danlos syndromes can affect the function of the heart and aorta. Cleveland Clinic experts discuss surgical options, recovery and expected outcomes for those with connective tissue disorders. Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469. Meet the Presente...

Connective tissue disorders like Marfan, Loeys-Dietz, and Ehlers-Danlos syndromes can affect the function of the heart and aorta. Cleveland Clinic experts discuss the diagnosis of these genetic conditions and indications for heart and aorta treatment in patients with connective tissue disorders in part one of this two-part series. Meet the Presenters: Lars Svensson, MD, PhD Chief of the Sydell and...

G. Jay Bishop, MD, and Aravinda Nanjundappa, MBBS, MD, explore Cleveland Clinic’s latest advances in vascular medicine, from research on aortic aneurysm biomarkers to innovative treatments for pulmonary embolism, hypertension, and peripheral artery disease. Learn how multidisciplinary teams are transforming care with new research on cutting-edge therapies.  Looking to refer a patient? Please reach...

Learn about the promising results of a fixed-dose combination therapy trial that achieved up to a 50% reduction in LDL cholesterol. Steven Nissen, MD and Ashish Sarraju, MD discuss how this CETP inhibitor-based therapy compares to monotherapies, its potential role in treating high-risk cardiovascular patients, and what it could mean for the future of hyperlipidemia management. Looking to refer a p...

Persistent or recurrent atrial fibrillation (AFib) following ablation remains a clinical challenge, especially when it occurs more than three months after an ablation. Expert Cleveland Clinic electrophysiologists discuss the causes for recurrent AFib and review current management strategies, including redo ablation and surgical intervention. Meet the presenters: Oussama Wazni, MD, MBA, Section Hea...