Dr. Brad Lewis, Machaon Diagnostics

Blood, Sweat and Smears - A Machaon Diagnostics Podcast

Health EN ↓ 51 episodes

Blood, Sweat and Smears is a podcast focused on thrombosis and hemostasis and is hosted by Benign Hematologist, Dr. Brad Lewis. Dr. Lewis shares some of his knowledge built over decades of experience in hematology and laboratory testing.

Author

Dr. Brad Lewis, Machaon Diagnostics

Category

Health

Podcast website

www.machaondiagnostics.com

Latest episode

Jun 22, 2026

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Episodes

Diagnosing Heparin-Induced Thrombocytopenia (HIT) and the role of HIPA Testing 07.08.2023

In this podcast, our Medical Director, Dr. Brad Lewis, discusses heparin-induced thrombocytopenia, also known as HIT.  Dr. Lewis addresses what HIT is, how to diagnose and interpret testing, and the role of functional testing like the HIPA (Heparin-Induced Platelet Antibody) test.

Diagnosing and treating Hemophagocytic lymphohistiocytosis (HLH) 24.02.2023

In this podcast, our Medical Director, Dr. Brad Lewis, talks with Dr. Scott Canna, from the Division of Rheumatology and the Immune Dysregulation Program at Children's Hospital of Philadelphia. Dr. Lewis and Dr. Canna discuss Hemophagocytic lymphohistiocytosis (HLH); what HLH is, treating and diagnosing HLH, and infections that make you particularly worried about the possibility of HLH develo...

Diagnosing and treating aHUS in a 40-day-old patient 16.02.2023

In this podcast, our Medical Director, Brad Lewis, discusses a  pediatric case of aHUS with Dr. Amara Finch, a Pediatric Resident Physician at the University of Utah. Dr. Finch presents a fascinating case of atypical hemolytic uremic syndrome (aHUS) in a 40-day-old patient. Using Machaon Diagnostics' fast turnaround time, physicians were able to get the results for their aHUS Genetic Panel, s...

Renal transplants and the roles of testing around it 08.08.2022

In this podcast, our Medical Director, Brad Lewis, talks with Dr. Christina Klein, a transplant nephrologist and the head of the transplant program at Piedmont Transplant Institute in Atlanta, GA.  Dr. Lewis and Dr. Klein discuss renal transplants and the different roles of testing around renal transplants (i.e. gene sequencing and soluble MAC).  They also discuss the functions of genetic testing...

Understanding next-generation sequencing (NGS) 30.06.2022

In this podcast, our Medical Director, Brad Lewis, continues his conversation with Jamey Kain, Vice President of Genetic Innovation here at Machaon.  Brad and Jamey discuss what next-generation sequencing (NGS) is, why it's important and some of the issues we face with NGS. Don't forget, Machaon offers genetic testing STAT results in 48 hours!

How to choose panels for next-generation sequencing (NGS) 14.04.2022

In this podcast, our Medical Director, Brad Lewis, talks with Jamey Kain, Vice President of Genetic Innovation here at Machaon. Brad and Jamey discuss how we design our genetic panels, what goes in, what stays out and how we think about clinical utility and turnaround time considerations. Don't forget, Machaon offers genetic testing STAT results in 48 hours!

Psychological and Emotional Impact of VTE Diagnosis; Improving Patient Outcomes 12.10.2021

Join Dr. Kerstin de Wit and our Medical Director, Dr. Brad Lewis, discuss the importance of accessing and educating patients with newly diagnosed venous thrombotic disease. Many patient factors, including age, sex, activity and knowledge levels should be considered to optimize acceptance and disease management. Providers can help patients minimize distress with careful questioning and listening sk...

From CLS to CEO, the story of Machaon Diagnostics 21.09.2021

In this episode we hear an interview with Mike Ero, Machaon Diagnostics' Founder and CEO. A Clinical Laboratory Scientist (CLS) who added an MBA, Mike started Machaon Diagnostics back in 2003 at the age of 29. Just how did all of that come about? Listen and find out.  We hope you find our origin story interesting. You'll get a good sense of why we were founded and the mission we are fulf...

Bleeding Disorders in Women: Considerations pre, during & postpartum 17.09.2021

Andra James, MD, MPH is a Professor of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine at Duke University Center, and consulting professor of Medicine, Division of Hematology. She is also the founder of Duke University's Women's Hemostasis and Thrombosis Clinic.  Dr. James and Machaon Diagnostics' Medical Director, Dr. Brad Lewis, discuss the various approaches to m...

COVID-19 VITT - What we know so far 07.05.2021

Our Medical Director, Brad Lewis, MD, discusses COVID-19 Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) and diagnostic strategies. 

PAI-1 with Dr. Brad Lewis 14.03.2021

In this episode Dr. Brad Lewis talks about PAI-1, testing for PAI-1 and where things look to be heading for the future of this gene and conditions associated with it. We released this episode to coincide with Pi Day (3.14).

Challenges in diagnosing Hemophagocytic Lymphohistiocytosis (HLH) 16.12.2020

Join Michelle Hermiston, MD, PhD - Associate Professor of Pediatrics (Pediatric Hematologist/Oncologist) at UCSF and our Medical Director, Brad Lewis, MD, discuss the challenges of diagnosing Hemophagocytic Lymphohistiocytosis or HLH, possible triggers and approach to management. If you are interested in our 48-hour STAT check out the link for more information 👉 http://bit.ly/37rm28H. We can send...

aHUS in Pregnancy 18.08.2020

Our Medical Director, Brad Lewis, MD, discusses aHUS/TMAs in pregnancy with Richard Burwick, MD, MPH - Assistant Professor, Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Cedars-Sinai Medical Center. If you are interested in our 48-hour STAT aHUS Testing please let us know. We can send you draw kits and are happy to talk you through the process/details.

Hypercoagulability and COVID-19 (Updated March 25, 2020) 25.03.2020

Our Medical Director, Brad Lewis, addresses a number of questions around hypercoagulability and COVID-19.

soluble Complement 5b-9 (sC5b-9) 26.02.2020

Dr. Brad Lewis discusses sC5b-9 in this podcast addressing; what sC5b-9 testing is, why you want to know about this test and when to use it. Dr. Lewis also explores how it helps when trying to confirm a diagnosis. 

Hemophagocytic lymphohistiocytosis (HLH) 08.11.2019

Dr. Brad Lewis discusses hemophagocytic lymphohistiocytosis (HLH); when you want to think about HLH, why you want to think about HLH, and how to diagnose this disorder. 

Blood, Sweat and Smears - Post-Bone Marrow Transplant TMA 18.06.2019

Dr. Lewis discusses TMAs in the post-BMT setting, recent research into the topic, when to think about it and what to do about it. 

Hypercoagulability explained for patients 28.03.2019
Review of TMAs 27.02.2019
Hypercoagulability Testing 24.01.2019
Lab Testing for Patients Taking Hemlibra (Emicizumab-kxwh) 20.12.2018
Blood, Sweat and Smears - Common errors and misconceptions around coagulation 02.10.2018
Blood, Sweat and Smears - What to make of an equivocal aHUS result 20.09.2018
Blood, Sweat and Smears - Diagnosing Thrombotic Microangiopathies 07.09.2018
Blood, Sweat and Smears - Hemophilia Genetic Testing 17.08.2018

Dr. Brad Lewis discusses considerations for genetic testing when it comes to hemophilia and rare forms of von Willebrand disease.

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